Page last updated: 2024-10-26

erythrosine and Neuroblastoma

erythrosine has been researched along with Neuroblastoma in 40 studies

Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" We try to prevent the apoptosis induced by rotenone toxicity with 50 microM myricetin, 100 microM fraxetin and 100 microM N-acetylcysteine (NAC) that protect against reactive oxygen species (ROS), on SH-SY5Y human neuroblastoma cell line."7.72Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells. ( Andres, D; Benedi, J; Cascales, M; Molina-Jiménez, MF; Sánchez-Reus, MI, 2004)
" We try to prevent the apoptosis induced by rotenone toxicity with 50 microM myricetin, 100 microM fraxetin and 100 microM N-acetylcysteine (NAC) that protect against reactive oxygen species (ROS), on SH-SY5Y human neuroblastoma cell line."3.72Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells. ( Andres, D; Benedi, J; Cascales, M; Molina-Jiménez, MF; Sánchez-Reus, MI, 2004)
"Adding the membrane-permeant oxidant tert-butylhydroperoxide (t-BOOH) to the incubation medium, in SH-SY5Y human neuroblastoma cells, induced a marked and progressive concentration-dependent (300, 500 and 1000 microM) increase of free radical production, as evaluated by the fluorescent probe 2',7'-dichlorodihydrofluorescein diacetate (DCFH-DA) and of the intracellular Ca(2+) ion concentrations [Ca(2+)](i)."3.70In the neuronal cell line SH-SY5Y, oxidative stress-induced free radical overproduction causes cell death without any participation of intracellular Ca(2+) increase. ( Amoroso, S; Annunziato, L; Cataldi, M; Di Renzo, G; Gioielli, A, 1999)
" In the current paper, we present evidence that the putative neurotoxic fragment 25-35 of amyloid beta causes loss of trypan blue exclusion in differentiated mouse neuroblastoma N1E-115 cells which suggests a potential neurotoxic effect."3.69An artifact associated with using trypan blue exclusion to measure effects of amyloid beta on neuron viability. ( el-Fakahany, EE; Hu, J, 1994)
"The effect of prolonged exposure to ammonia on fluid-phase, receptor-mediated, and adsorptive (non specific) endocytosis in cultured neuroblastoma (Neuro-2a) cells were studied using fluorescein-labeled dextran, concanavalin A conjugated with fluorescein isothiocyanate, and cationized ferritin as tracers."3.67Effects of prolonged exposure to ammonia on fluid-phase, receptor-mediated, and adsorptive (non specific) endocytosis in cultured neuroblastoma cells. A flow-cytometry and cytochemical study. ( Báguena-Cervellera, R; Grisolia, S; O'Connor, JE; Renau-Piqueras, J, 1987)
" Pituitary adenylate cyclase-activating polypeptide (PACAP) is an endogenous 38 amino-acid peptide with demonstrated protection against neuronal injury, trauma as well as various endogenous and exogenous toxic agents."1.46PACAP Protects Against Ethanol and Nicotine Toxicity in SH-SY5Y Cells: Implications for Drinking-Smoking Co-morbidity. ( Csoka, AB; Getachew, B; Khundmiri, SJ; Manavalan, S; Manaye, KF; McKinley, R; Reglodi, D; Tamas, A; Tizabi, Y, 2017)
"Neuroblastoma is the most common extra-cranial solid tumor in childhood; and patients in stage IV of the disease have a high propensity for tumor recurrence."1.43Redox balance influences differentiation status of neuroblastoma in the presence of all-trans retinoic acid. ( Kiningham, KK; McCormick, ML; Silvis, AM; Spitz, DR, 2016)
"Our results demonstrate that scrapie infection leads to changes in cellular iron metabolism, affecting both total cellular and cytosolic free iron, and the activities and expression of major regulators of cellular iron homeostasis."1.33Changed iron regulation in scrapie-infected neuroblastoma cells. ( Bedecs, K; Fernaeus, S; Hälldin, J; Land, T, 2005)
" A modified 'amyloid cascade' hypothesis for Alzheimer's disease states that prefibrillar oligomers, also called amyloid-beta-derived diffusible ligands or globular oligomers, are the responsible toxic agent."1.33Interaction of human stefin B in the prefibrillar oligomeric form with membranes. Correlation with cellular toxicity. ( Anderluh, G; Ceru, S; Gutierrez-Aguirre, I; Kopitar-Jerala, N; Macek, P; Rabzelj, S; Turk, V; Zerovnik, E, 2005)
"Coenzyme Q10 (CoQ10) is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects."1.33Coenzyme Q10 protects SHSY5Y neuronal cells from beta amyloid toxicity and oxygen-glucose deprivation by inhibiting the opening of the mitochondrial permeability transition pore. ( Cao, CM; Li, G; Yang, ES; Zou, LY, 2005)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19907 (17.50)18.7374
1990's13 (32.50)18.2507
2000's12 (30.00)29.6817
2010's7 (17.50)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Yang, J1
Liu, B1
Xu, Z1
Feng, M1
Manavalan, S1
Getachew, B1
Manaye, KF1
Khundmiri, SJ1
Csoka, AB1
McKinley, R1
Tamas, A1
Reglodi, D1
Tizabi, Y1
Yang, YH1
Hsieh, TJ1
Tsai, ML1
Chen, CH1
Lin, HT1
Wu, SJ1
Silvis, AM1
McCormick, ML1
Spitz, DR1
Kiningham, KK1
Rajagopalan, S1
Rane, A1
Chinta, SJ1
Andersen, JK1
Hatcher, JM1
Delea, KC1
Richardson, JR1
Pennell, KD1
Miller, GW1
Giménez-Xavier, P1
Francisco, R1
Santidrián, AF1
Gil, J1
Ambrosio, S1
Peritore, CS1
Ho, A1
Yamamoto, BK1
Schaus, SE1
Hadzhieva, M1
Kirches, E1
Wilisch-Neumann, A1
Pachow, D1
Wallesch, M1
Schoenfeld, P1
Paege, I1
Vielhaber, S1
Petri, S1
Keilhoff, G1
Mawrin, C1
Pontiki, E1
Kontogiorgis, C1
Xu, Y1
Hadjipavlou-Litina, D1
Luo, Y1
Sebastià, J1
Cristòfol, R1
Martín, M1
Rodríguez-Farré, E1
Sanfeliu, C1
Molina-Jiménez, MF1
Sánchez-Reus, MI1
Andres, D1
Cascales, M1
Benedi, J1
Yu, Z1
Li, W1
Hillman, J1
Brunk, UT1
Fernaeus, S1
Hälldin, J1
Bedecs, K1
Land, T1
Anderluh, G1
Gutierrez-Aguirre, I1
Rabzelj, S1
Ceru, S1
Kopitar-Jerala, N1
Macek, P1
Turk, V1
Zerovnik, E1
Schulz, I1
Zeitschel, U1
Rudolph, T1
Ruiz-Carrillo, D1
Rahfeld, JU1
Gerhartz, B1
Bigl, V1
Demuth, HU1
Rossner, S1
Wallace, DR1
Dodson, S1
Nath, A1
Booze, RM1
Li, G1
Zou, LY1
Cao, CM1
Yang, ES1
Kawasaki, Y1
Amano, T1
Veenstra, RD3
Wang, HZ3
Beyer, EC3
Brink, PR3
Ramanan, SV1
Beblo, DA1
Chilton, MG1
Harris, AL1
Hu, J1
el-Fakahany, EE1
Faure, MP1
Gaudreau, P1
Shaw, I1
Cashman, NR1
Beaudet, A1
Crowe, WE1
Altamirano, J2
Huerto, L1
Alvarez-Leefmans, FJ2
Kito, K1
Ito, T1
Sakaki, Y1
Brodwick, MS1
Fall, CP1
Bennett, JP1
Adler, M1
Shafer, H1
Hamilton, T1
Petrali, JP1
Amoroso, S1
Gioielli, A1
Cataldi, M1
Di Renzo, G1
Annunziato, L1
Clark, HA1
Kopelman, R1
Tjalkens, R1
Philbert, MA1
Chen, RL1
Reynolds, CP1
Seeger, RC1
Woollacott, AJ1
Simpson, PB1
Sanger, JW1
Sabatier, JM1
Vives, E1
Mabrouk, K1
Benjouad, A1
Rochat, H1
Duval, A1
Hue, B1
Bahraoui, E1
Reisner, Y1
Gan, J1
Báguena-Cervellera, R1
Renau-Piqueras, J1
O'Connor, JE1
Grisolia, S1
Notter, MF1
Leary, JF1
Kilpatrick-Smith, L1
Maniara, G1
Vanderkooi, JM1
Erecinska, M1
Waghe, M1
Kumar, S1
Steward, JK1

Other Studies

40 other studies available for erythrosine and Neuroblastoma

ArticleYear
Silencing of Circ_0135889 Restrains Proliferation and Tumorigenicity of Human Neuroblastoma Cells.
    The Journal of surgical research, 2022, Volume: 279

    Topics: Annexin A5; Cell Line, Tumor; Cell Movement; Cell Proliferation; Child; Child, Preschool; Deoxyuridi

2022
PACAP Protects Against Ethanol and Nicotine Toxicity in SH-SY5Y Cells: Implications for Drinking-Smoking Co-morbidity.
    Neurotoxicity research, 2017, Volume: 32, Issue:1

    Topics: Calcium; Cell Line, Tumor; Cell Survival; Central Nervous System Depressants; Dose-Response Relation

2017
Neuroprotective effects of Hu-Yi-Neng, a diet supplement, on SH-SY5Y human neuroblastoma cells.
    The journal of nutrition, health & aging, 2014, Volume: 18, Issue:2

    Topics: Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Dietary Supplements; Fluoresceins; Heme Ox

2014
Redox balance influences differentiation status of neuroblastoma in the presence of all-trans retinoic acid.
    Redox biology, 2016, Volume: 7

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Fluoresceins; Gene Expression Regulat

2016
Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Jan-27, Volume: 36, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Disease Models, Animal; Fluoresceins; Gene Expression Regulation

2016
Disruption of dopamine transport by DDT and its metabolites.
    Neurotoxicology, 2008, Volume: 29, Issue:4

    Topics: Animals; Behavior, Animal; Cell Line, Tumor; Chromatography, High Pressure Liquid; DDT; Dopamine; Do

2008
Effects of dopamine on LC3-II activation as a marker of autophagy in a neuroblastoma cell model.
    Neurotoxicology, 2009, Volume: 30, Issue:4

    Topics: Analysis of Variance; Apoptosis Regulatory Proteins; Autophagy; Caspase 3; Cell Line, Tumor; Cell Su

2009
Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells.
    Neuroreport, 2012, Dec-05, Volume: 23, Issue:17

    Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Drug Interact

2012
Dysregulation of iron protein expression in the G93A model of amyotrophic lateral sclerosis.
    Neuroscience, 2013, Jan-29, Volume: 230

    Topics: Cation Transport Proteins; Cell Differentiation; Cell Line, Tumor; Fluoresceins; Gene Expression Reg

2013
New lipoxygenase inhibitors of reactive oxygen species production in cellular models of amyloid (A2) toxicities.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 34, Issue:1

    Topics: Amyloid; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Cell Line, Tumor; Cell Survi

2013
Evaluation of fluorescent dyes for measuring intracellular glutathione content in primary cultures of human neurons and neuroblastoma SH-SY5Y.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2003, Volume: 51, Issue:1

    Topics: Antioxidants; Biological Assay; Bridged Bicyclo Compounds; Buthionine Sulfoximine; Cell Death; Cell

2003
Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells.
    Brain research, 2004, May-29, Volume: 1009, Issue:1-2

    Topics: Acetylcysteine; Analysis of Variance; Apoptosis; Blotting, Southern; Cell Line, Tumor; Cell Survival

2004
Human neuroblastoma (SH-SY5Y) cells are highly sensitive to the lysosomotropic aldehyde 3-aminopropanal.
    Brain research, 2004, Aug-06, Volume: 1016, Issue:2

    Topics: Aldehydes; alpha-Tocopherol; Ammonium Chloride; Analysis of Variance; Annexin A5; Apoptosis; Cell Li

2004
Changed iron regulation in scrapie-infected neuroblastoma cells.
    Brain research. Molecular brain research, 2005, Feb-18, Volume: 133, Issue:2

    Topics: Animals; Blotting, Southern; Blotting, Western; Cell Line, Tumor; Deferoxamine; Electrophoretic Mobi

2005
Interaction of human stefin B in the prefibrillar oligomeric form with membranes. Correlation with cellular toxicity.
    The FEBS journal, 2005, Volume: 272, Issue:12

    Topics: Cell Membrane; Cystatin A; Cystatin B; Cystatins; Cysteine Proteinase Inhibitors; Fluoresceins; Huma

2005
Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion.
    Journal of neurochemistry, 2005, Volume: 94, Issue:4

    Topics: Alanine; Cell Line, Tumor; Fluoresceins; Glioma; Green Fluorescent Proteins; Humans; Immunohistochem

2005
Estrogen attenuates gp120- and tat1-72-induced oxidative stress and prevents loss of dopamine transporter function.
    Synapse (New York, N.Y.), 2006, Volume: 59, Issue:1

    Topics: Animals; Cell Line, Tumor; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; D

2006
Coenzyme Q10 protects SHSY5Y neuronal cells from beta amyloid toxicity and oxygen-glucose deprivation by inhibiting the opening of the mitochondrial permeability transition pore.
    BioFactors (Oxford, England), 2005, Volume: 25, Issue:1-4

    Topics: Amyloid beta-Peptides; Atractyloside; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Coenzymes; Fluo

2005
The change in membrane fluidity of neuroblastoma X glioma hybrid cells upon cell differentiation.
    FEBS letters, 1982, Apr-05, Volume: 140, Issue:1

    Topics: Cell Differentiation; Fluoresceins; Fluorescent Dyes; Glioma; Hybridomas; Membrane Fluidity; Microsc

1982
Selective dye and ionic permeability of gap junction channels formed by connexin45.
    Circulation research, 1994, Volume: 75, Issue:3

    Topics: Animals; Cell Line; Cell Membrane Permeability; Chickens; Connexins; Electric Conductivity; Fluoresc

1994
Connexin37 forms high conductance gap junction channels with subconductance state activity and selective dye and ionic permeabilities.
    Biophysical journal, 1994, Volume: 66, Issue:6

    Topics: Animals; Cell Line; Connexins; Electric Conductivity; Electrophysiology; Fluoresceins; Fluorescent D

1994
Selectivity of connexin-specific gap junctions does not correlate with channel conductance.
    Circulation research, 1995, Volume: 77, Issue:6

    Topics: Animals; Blotting, Northern; Cells, Cultured; Chickens; Connexins; Diffusion; Electric Conductivity;

1995
An artifact associated with using trypan blue exclusion to measure effects of amyloid beta on neuron viability.
    Life sciences, 1994, Volume: 55, Issue:13

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Membrane; Cell Survival; Female; Fluorescein

1994
Synthesis of a biologically active fluorescent probe for labeling neurotensin receptors.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1994, Volume: 42, Issue:6

    Topics: Amino Acids; Animals; Binding, Competitive; Brain; Cell Line; Flow Cytometry; Fluoresceins; Fluoresc

1994
Volume changes in single N1E-115 neuroblastoma cells measured with a fluorescent probe.
    Neuroscience, 1995, Volume: 69, Issue:1

    Topics: Animals; Calcium; Digitonin; Fluoresceins; Fluorescent Dyes; Indicators and Reagents; Intracellular

1995
Fluorescent differential display analysis of gene expression in differentiating neuroblastoma cells.
    Gene, 1997, Jan-03, Volume: 184, Issue:1

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Cell Differentiation; Clone Cells; Cloning,

1997
Regulatory volume decrease and intracellular Ca2+ in murine neuroblastoma cells studied with fluorescent probes.
    The Journal of general physiology, 1998, Volume: 112, Issue:2

    Topics: Animals; Calcium; Cell Size; Chelating Agents; Egtazic Acid; Fluoresceins; Fluorescent Dyes; Fura-2;

1998
Characterization and time course of MPP+ -induced apoptosis in human SH-SY5Y neuroblastoma cells.
    Journal of neuroscience research, 1999, Mar-01, Volume: 55, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Cell Cycle; Cell Membrane; Cell Nucleus; DNA Fragmentation;

1999
Cytotoxic actions of the heavy metal chelator TPEN on NG108-15 neuroblastoma-glioma cells.
    Neurotoxicology, 1999, Volume: 20, Issue:4

    Topics: Animals; Apoptosis; Biomarkers; Cell Aggregation; Cell Nucleus; Cell Survival; Chelating Agents; Chr

1999
In the neuronal cell line SH-SY5Y, oxidative stress-induced free radical overproduction causes cell death without any participation of intracellular Ca(2+) increase.
    Biochimica et biophysica acta, 1999, Nov-11, Volume: 1452, Issue:2

    Topics: Calcium; Cell Death; Cell Survival; Chelating Agents; Cytosol; Egtazic Acid; Fluoresceins; Free Radi

1999
Optical nanosensors for chemical analysis inside single living cells. 2. Sensors for pH and calcium and the intracellular application of PEBBLE sensors.
    Analytical chemistry, 1999, Nov-01, Volume: 71, Issue:21

    Topics: Calcium; Calibration; Cell Membrane Permeability; Coloring Agents; Dinitrobenzenes; Fluoresceins; Fl

1999
Neutrophils are cytotoxic and growth-inhibiting for neuroblastoma cells with an anti-GD2 antibody but, without cytotoxicity, can be growth-stimulating.
    Cancer immunology, immunotherapy : CII, 2000, Volume: 48, Issue:11

    Topics: Antibodies, Monoclonal; Antibody-Dependent Cell Cytotoxicity; Antigens, Neoplasm; Cell Count; Cell D

2000
High throughput fluorescence assays for the measurement of mitochondrial activity in intact human neuroblastoma cells.
    Journal of biomolecular screening, 2001, Volume: 6, Issue:6

    Topics: Benzimidazoles; Carbocyanines; Fluoresceins; Fluorescence; Fluorescent Dyes; Humans; Microscopy, Con

2001
Intracellular localization of actin with fluorescently labelled heavy meromyosin.
    Cell and tissue research, 1975, Aug-27, Volume: 161, Issue:4

    Topics: Actins; Animals; Binding Sites; Cell Movement; Chickens; Connective Tissue; Connective Tissue Cells;

1975
Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1.
    Journal of virology, 1991, Volume: 65, Issue:2

    Topics: Action Potentials; Animals; Binding Sites; Cell Line; Cockroaches; Fluorescein-5-isothiocyanate; Flu

1991
Differential binding of soybean agglutinin to human neuroblastoma cell lines: potential application to autologous bone marrow transplantation.
    Cancer research, 1985, Volume: 45, Issue:9

    Topics: Agglutination; Bone Marrow Transplantation; Cell Line; Chromatography, Agarose; Fluorescein-5-isothi

1985
Effects of prolonged exposure to ammonia on fluid-phase, receptor-mediated, and adsorptive (non specific) endocytosis in cultured neuroblastoma cells. A flow-cytometry and cytochemical study.
    Histochemistry, 1987, Volume: 87, Issue:5

    Topics: Acetylcholinesterase; Acid Phosphatase; Ammonia; Animals; Concanavalin A; Dextrans; Endocytosis; Fer

1987
Surface glycoproteins of differentiating neuroblastoma cells analyzed by lectin binding and flow cytometry.
    Cytometry, 1987, Volume: 8, Issue:5

    Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Cell Differentiation; Cell Line; Concanavalin A; Fl

1987
Cellular effects of endotoxin in vitro: mobility of endotoxin in the plasma membrane of hepatocytes and neuroblastoma cells.
    Biochimica et biophysica acta, 1985, Nov-20, Volume: 847, Issue:2

    Topics: Animals; Cell Line; Cell Membrane; Endotoxins; Fluorescein-5-isothiocyanate; Fluoresceins; In Vitro

1985
The lack of effect of mouse epidermal growth factor (EGF) and its anti-serum on human tissues.
    European journal of cancer, 1973, Volume: 9, Issue:8

    Topics: Adenocarcinoma; Animals; Breast; Breast Neoplasms; Culture Techniques; Female; Fluoresceins; Growth

1973