Page last updated: 2024-08-23

simvastatin and Neuroblastoma

simvastatin has been researched along with Neuroblastoma in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Ding, HF; Ding, J; Dong, Z; Liu, K; Liu, M; Sudarshan, S; Tran, GB; Ye, B; Yu, Y; Zha, Y1
Anderson, CC; Kuzyk, CL; Roede, JR1
Ali-Rahmani, F; Connor, JR; Huang, MA; Lee, SY; Schengrund, CL1
Astort, F; Ferraro, SA; Tasat, DR; Yakisich, JS1
Dafa-Berger, A; Dyer, MD; Fishman, D; Katze, MG; Paeper, B; Proll, SC; Rager-Zisman, B; Robinzon, S; Rom, S; Teal, TH1
Ambros, PF; Hohenegger, M; Lehner, C; Sieczkowski, E1
Di Benedetto, B; Ganal, V; Holsboer, F; Kessler, JS; Kirmeier, T; Nothdurfter, C; Rammes, G; Rein, T; Rupprecht, R; Tanasic, S; Wagner, EM1
Burgos, JS; Ramirez, C; Ramos, MC; Sierra, S; Velasco, J1
Carter, TL; Ehrlich, ME; Gandy, S; Pedrini, S; Petanceska, S; Prendergast, G1
Bate, C; Williams, A1
Galli, C; Marangoni, F; Petroni, A; Risé, P; Visioli, F1

Other Studies

11 other study(ies) available for simvastatin and Neuroblastoma

ArticleYear
Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma.
    Cancer research, 2023, 07-05, Volume: 83, Issue:13

    Topics: Animals; Caffeine; Cholesterol; Dietary Supplements; Forkhead Box Protein M1; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Mice; Mice, Transgenic; Neuroblastoma; Purinergic P1 Receptor Antagonists; Simvastatin

2023
Simvastatin Induces Delayed Apoptosis Through Disruption of Glycolysis and Mitochondrial Impairment in Neuroblastoma Cells.
    Clinical and translational science, 2020, Volume: 13, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Drug Screening Assays, Antitumor; Energy Metabolism; Humans; Mevalonic Acid; Mitochondria; Neuroblastoma; Simvastatin; Ubiquinone; Warburg Effect, Oncologic

2020
C282Y-HFE gene variant affects cholesterol metabolism in human neuroblastoma cells.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Alleles; Androstenes; Azetidines; Cell Line, Tumor; Cell Survival; Cholesterol; Ezetimibe; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Variation; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Iron; Membrane Proteins; Neuroblastoma; Oxidoreductases; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Risk Factors; Simvastatin; Sphingolipids

2014
Particulate matter cytotoxicity in cultured SH-SY5Y cells is modulated by simvastatin: Toxicological assessment for oxidative damage.
    Neurotoxicology, 2016, Volume: 53

    Topics: Aging; Anticholesteremic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Coal Ash; Dose-Response Relationship, Drug; Environmental Pollutants; Humans; Neuroblastoma; NF-E2-Related Factor 2; Oxidation-Reduction; Reactive Oxygen Species; Simvastatin; Superoxides

2016
Impaired cholesterol biosynthesis in a neuronal cell line persistently infected with measles virus.
    Journal of virology, 2009, Volume: 83, Issue:11

    Topics: Acute Disease; Animals; Cell Line, Tumor; Cholesterol; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Measles virus; Membrane Microdomains; Mice; Neuroblastoma; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Simvastatin

2009
Double impact on p-glycoprotein by statins enhances doxorubicin cytotoxicity in human neuroblastoma cells.
    International journal of cancer, 2010, May-01, Volume: 126, Issue:9

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glycosylation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neuroblastoma; Simvastatin

2010
Impact of lipid raft integrity on 5-HT3 receptor function and its modulation by antidepressants.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:7

    Topics: Animals; Anticholesteremic Agents; Antidepressive Agents; beta-Cyclodextrins; Biophysics; Cholesterol; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fluoxetine; Humans; Imidazoles; Membrane Microdomains; Membrane Potentials; Mice; Neuroblastoma; Patch-Clamp Techniques; Receptors, Serotonin, 5-HT3; Serotonin; Simvastatin; Sulfhydryl Compounds; Time Factors; Transfection

2010
Simvastatin modulates the Alzheimer's disease-related gene seladin-1.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 28, Issue:2

    Topics: Animals; Anticholesteremic Agents; Brain; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Mice; Nerve Tissue Proteins; Neuroblastoma; Oxidoreductases Acting on CH-CH Group Donors; RNA, Messenger; Simvastatin; Time Factors; Up-Regulation

2012
Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK.
    PLoS medicine, 2005, Volume: 2, Issue:1

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Neuroblastoma; Phosphorylation; Protein Serine-Threonine Kinases; Pyrroles; rho-Associated Kinases; Simvastatin; Tumor Cells, Cultured

2005
Squalestatin protects neurons and reduces the activation of cytoplasmic phospholipase A2 by Abeta(1-42).
    Neuropharmacology, 2007, Volume: 53, Issue:2

    Topics: Amyloid beta-Peptides; Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Caveolin 1; Cell Survival; Cells, Cultured; Cytoplasm; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Immunoprecipitation; Mice; Neuroblastoma; Neurons; Neuroprotective Agents; Peptide Fragments; Pharmacokinetics; Phospholipases A2; Simvastatin

2007
Manipulation of the fate of long chain polyunsaturated fatty acids in cultured cells.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 57, Issue:1

    Topics: Arachidonic Acid; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line; Cholesterol; Enzyme Inhibitors; Ethanol; Fatty Acids, Unsaturated; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Linoleic Acid; Linoleic Acids; Liver Neoplasms; Lovastatin; Mevalonic Acid; Monocytes; Neuroblastoma; Simvastatin; Tumor Cells, Cultured

1997