ibudilast has been researched along with Neuroblastoma in 1 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In conclusion, these results suggest that tacrolimus translocation into the brain and neuronal damage in the cerebral cortex and CA1 are the underlying mechanisms of tacrolimus-induced neurotoxicity and that ibudilast could be a protective agent against this adverse event." | 1.72 | Neuroprotective effects of ibudilast against tacrolimus induced neurotoxicity. ( Egashira, N; Fu, R; Hirota, T; Ieiri, I; Matsukane, R; Tsuchiya, Y; Yamamoto, S; Zhang, W, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, W | 1 |
| Matsukane, R | 1 |
| Egashira, N | 1 |
| Tsuchiya, Y | 1 |
| Fu, R | 1 |
| Yamamoto, S | 1 |
| Hirota, T | 1 |
| Ieiri, I | 1 |
1 other study available for ibudilast and Neuroblastoma
| Article | Year |
|---|---|
Neuroprotective effects of ibudilast against tacrolimus induced neurotoxicity.
Topics: Animals; Humans; Neuroblastoma; Neuroprotective Agents; Neurotoxicity Syndromes; Pyridines; Rats; Ra | 2022 |