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phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide and Neuroblastoma

phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide has been researched along with Neuroblastoma in 10 studies

phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide: cyclic somatostatin octapeptide analog with high affinity & selectivity toward mu opioid receptors

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Earlier studies demonstrated Arc induction in discrete brain regions by several psychoactive substances, including drugs of abuse."5.33Morphine activates Arc expression in the mouse striatum and in mouse neuroblastoma Neuro2A MOR1A cells expressing mu-opioid receptors. ( Bilecki, W; Przewłocki, R; Urbański, MJ; Wawrzczak-Bargieła, A; Ziółkowska, B, 2005)
"The irreversible opioid receptor antagonists naloxonazine and beta-funaltrexamine have been used to determine whether multiple mu-opioid receptors exist on undifferentiated SH-SY5Y human neuroblastoma cells."3.69Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine. ( Elliott, J; Lambert, DG; Smart, D; Traynor, JR, 1994)
"Earlier studies demonstrated Arc induction in discrete brain regions by several psychoactive substances, including drugs of abuse."1.33Morphine activates Arc expression in the mouse striatum and in mouse neuroblastoma Neuro2A MOR1A cells expressing mu-opioid receptors. ( Bilecki, W; Przewłocki, R; Urbański, MJ; Wawrzczak-Bargieła, A; Ziółkowska, B, 2005)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's6 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bennett, L1
Ratka, A1
Sakaguchi, M1
Murayama, K1
Jinsmaa, Y1
Yoshikawa, M1
Matsumura, E1
Liu, AM1
Wong, YH1
Ziółkowska, B1
Urbański, MJ1
Wawrzczak-Bargieła, A1
Bilecki, W1
Przewłocki, R1
Börner, C1
Stumm, R1
Höllt, V1
Kraus, J1
Elliott, J1
Smart, D1
Lambert, DG1
Traynor, JR1
Carter, BD1
Medzihradsky, F1
Law, PY1
Tine, SJ1
McLeod, LA1
Loh, HH1
Toll, L2

Other Studies

10 other studies available for phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide and Neuroblastoma

ArticleYear
Delta opioid receptors are involved in morphine-induced inhibition of luteinizing hormone releasing hormone in SK-N-SH cells.
    Neuropeptides, 2003, Volume: 37, Issue:5

    Topics: Analgesics, Opioid; Cell Line, Tumor; Dose-Response Relationship, Drug; Gonadotropin-Releasing Hormo

2003
Neurite outgrowth-stimulating activities of beta-casomorphins in Neuro-2a mouse neuroblastoma cells.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:12

    Topics: Animals; Brain Neoplasms; Caseins; Cell Differentiation; Cyclic AMP; Endorphins; Guinea Pigs; Ileum;

2003
Mu-opioid receptor-mediated phosphorylation of IkappaB kinase in human neuroblastoma SH-SY5Y cells.
    Neuro-Signals, 2005, Volume: 14, Issue:3

    Topics: Analgesics, Opioid; Analysis of Variance; Blotting, Western; Cell Line, Tumor; Dose-Response Relatio

2005
Morphine activates Arc expression in the mouse striatum and in mouse neuroblastoma Neuro2A MOR1A cells expressing mu-opioid receptors.
    Journal of neuroscience research, 2005, Nov-15, Volume: 82, Issue:4

    Topics: AIDS-Related Complex; Analysis of Variance; Animals; Blotting, Western; Cell Line, Tumor; Corpus Str

2005
Comparative analysis of mu-opioid receptor expression in immune and neuronal cells.
    Journal of neuroimmunology, 2007, Volume: 188, Issue:1-2

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Embryo, Mammalian; Gene Expression Regulation

2007
Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine.
    European journal of pharmacology, 1994, Aug-16, Volume: 268, Issue:3

    Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-Me

1994
Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, May-01, Volume: 90, Issue:9

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Analgesics; Animals; Antibodies; Cell Membrane; Clone Ce

1993
Association of a lower molecular weight protein to the mu-opioid receptor demonstrated by (125)I-beta-endorphin cross-linking studies.
    Journal of neurochemistry, 2000, Volume: 75, Issue:1

    Topics: Animals; beta-Endorphin; Cross-Linking Reagents; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Histidine; Iod

2000
Comparison of mu opioid receptor binding on intact neuroblastoma cells with guinea pig brain and neuroblastoma cell membranes.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: Animals; Brain; Cell Membrane; Guinea Pigs; Kinetics; Narcotic Antagonists; Neuroblastoma; Pertussis

1992
Mu-opioid receptor binding in intact SH-SY5Y neuroblastoma cells.
    European journal of pharmacology, 1990, Feb-06, Volume: 176, Issue:2

    Topics: Humans; Kinetics; Narcotics; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, mu; Somatostatin;

1990