pyridoxine has been researched along with Neuroblastoma in 7 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Excerpt | Relevance | Reference |
---|---|---|
" Isoniazid and its metabolites including acetylisoniazid, acetylhydrazine, diacetylhydrazine, isonicotinic acid and hydrazine were examined for their potential neurotoxic effects in cultured mouse dorsal root ganglion (DRG) neurons and mouse neuroblastoma x DRG neuron hybrid cell line N18D3." | 3.70 | Neurotoxicity of isoniazid and its metabolites in cultures of mouse dorsal root ganglion neurons and hybrid neuronal cell line. ( Kim, SU; Sanfeliu, C; Wright, JM, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (71.43) | 18.7374 |
1990's | 2 (28.57) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sanfeliu, C | 1 |
Wright, JM | 1 |
Kim, SU | 1 |
Plöchl, E | 2 |
Eastman, CL | 1 |
Guilarte, TR | 1 |
Kiley, VA | 1 |
Lazerson, J | 1 |
Shaw, KN | 1 |
Lieberman, E | 1 |
Koch, R | 1 |
Donnell, GN | 1 |
Mönch, E | 1 |
Stefan, H | 1 |
Käser, H | 1 |
1 review available for pyridoxine and Neuroblastoma
Article | Year |
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Cytotoxicity of 3-hydroxykynurenine: implications for CNS damage in neonatal vitamin B-6 deficiency.
Topics: Animals; Animals, Newborn; Antioxidants; Brain; Brain Chemistry; Cell Death; Hybrid Cells; Hydrolase | 1991 |
6 other studies available for pyridoxine and Neuroblastoma
Article | Year |
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Neurotoxicity of isoniazid and its metabolites in cultures of mouse dorsal root ganglion neurons and hybrid neuronal cell line.
Topics: Animals; Antitubercular Agents; Catalase; Cell Survival; Cells, Cultured; Dose-Response Relationship | 1999 |
[Genetic and biochemical studies on familial neuroblastoma].
Topics: Adrenal Gland Neoplasms; Coenzymes; Cystathionine; Cystathionine gamma-Lyase; Humans; Infant, Newbor | 1979 |
[Biochemical studies on familial neuroblastoma].
Topics: Adult; Child; Cystathionine; Female; Humans; Male; Mutation; Neuroblastoma; Oxalates; Pedigree; Pyri | 1978 |
Agenesis of the corpus callosum and neural crest tumors.
Topics: Abdominal Neoplasms; Abnormalities, Drug-Induced; Agenesis of Corpus Callosum; Child; Child, Prescho | 1986 |
Cystathioninuria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Carcinoma, Hepatocellular; Child, Preschoo | 1967 |
[Pepper type neuroblastoma with homocystinuria. Diagnosis, biochemistry and therapy].
Topics: Amino Acids; Catecholamines; Child, Preschool; Cyclophosphamide; Dopamine; Homocystinuria; Humans; L | 1970 |