| Assay ID | Title | Year | Journal | Article |
|---|
| AID1777425 | Disruption of MKK3/MYC protein-protein interaction in human HCT-116 cells transfected with VF-tagged MKK3 assessed as inhibition of MYC transcriptional activity at 0.5 to 2 uM measured after 12 hrs by Renilla luciferase based reporter assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1654637 | Substrate activity at aldehyde oxidase in human liver cytosol assessed as mono-oxide metabolite formation at 10 uM measured after 3 hrs in presence of AOX inhibitor hydralazine by UPLC/Q-TOF MS analysis | 2020 | Journal of medicinal chemistry, 06-25, Volume: 63, Issue:12
| Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model. |
| AID1240602 | Antiproliferative activity against human KARPAS299 cells after 2 to 4 days by ATPlite 1step luminescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17
| Design and synthesis of new non nucleoside inhibitors of DNMT3A. |
| AID736571 | Cell cycle arrest in human U937 cells at 5 to 50 uM after 30 hrs by FACS analysis | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line. |
| AID1777428 | Inhibition of cell migration in human HCT-116 cells measured after 18 hrs by scratch wound healing assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1169763 | Binding affinity to DNA (unknown origin) at 0.0625 to 0.5 mM by ethidium bromide dye based agarose gel electrophoresis method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21
| Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. |
| AID1073758 | Cytotoxicity against human PC3 cells after 48 hrs by trypan blue exclusion assay | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1777420 | Disruption of interaction between human recombinant GST-tagged MKK3/VF-tagged p38 expressed in HEK293T cells at 50 uM incubated for 30 mins by GST pull-down assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1777424 | Disruption of MKK3/MYC protein-protein interaction in human MDA-MB-468 cells assessed as decrease in MYC level at 1 to 20 uM measured by western blot assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1073766 | Inhibition of rat recombinant PRMT1 using histone as substrate preincubated for 5 mins followed by substrate addition measured after 6.5 mins by liquid scintillation counting analysis in presence of [methyl-3H]-AdoMet | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1654632 | Substrate activity at aldehyde oxidase in human liver cytosol at 10 uM measured after 3 hrs by UPLC/Q-TOF MS analysis | 2020 | Journal of medicinal chemistry, 06-25, Volume: 63, Issue:12
| Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model. |
| AID1777422 | Disruption of MKK3/MYC protein-protein interaction in human HCT-116 cells assessed as decrease in CDK4 level at 0.5 to 10 uM measured by western blot assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1073770 | Inhibition of human N-terminal 600 residues-deleted DNMT1 using hemimethylated (GAC)12 as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by liquid scintillation counting analysis in presence of [methyl-3H]-AdoMet | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1777434 | Disruption of interaction between human recombinant GST-tagged MKK3 expressed in HEK293T cells/MYC in human HCT116 cells incubated for 30 mins by GST pull-down assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1777437 | Disruption of MKK3/MYC protein-protein interaction in human MDA-MB-468 cells assessed as decrease in CDK4 level at 1 to 20 uM measured by western blot assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1777429 | Inhibition of cell migration in human HCT-116 cells assessed as relative wound density at 3 uM measured after 18 hrs by scratch wound healing assay (Rvb = 20%) | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID750165 | Cytotoxicity against human HCT116 cells assessed as viability | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1. |
| AID1447858 | Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex at CpG site at 32 uM after 1 hr by fluorescence assay relative to control | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells. |
| AID1073765 | Selectivity ratio of IC50 for rat recombinant PRMT1 to IC50 for human N-terminal 600 residues-deleted DNMT1 | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1452276 | Antiproliferative activity against human U937 cells after 72 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Jul-07, Volume: 134 | Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors. |
| AID750164 | Inhibition of DNMT1 in human HCT116 cells at 5 uM after 24 hrs by Western blot analysis relative to control | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1. |
| AID1199271 | Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biotinylated 45-bp unmethylated or hemimethylated oligonucleotide substrates and [3H]-AdoMet by liquid scinti | 2015 | Journal of medicinal chemistry, Mar-26, Volume: 58, Issue:6
| Targeting DNA methylation with small molecules: what's next? |
| AID1777426 | Disruption of MKK3/MYC protein-protein interaction in human MDA-MB-468 cells transfected with VF-tagged MKK3 assessed as inhibition of MYC transcriptional activity measured after 12 hrs by Renilla luciferase based reporter assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1777419 | Disruption of interaction between human recombinant GST-tagged MKK3 (1 to 210 residues)/VF-tagged MYC expressed in HEK293T cells measured after 2 hrs by TR-FRET assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1199269 | Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biotinylated 45-bp unmethylated or hemimethylated oligonucleotide substrates and [3H]-AdoMet by liquid scintil | 2015 | Journal of medicinal chemistry, Mar-26, Volume: 58, Issue:6
| Targeting DNA methylation with small molecules: what's next? |
| AID1777421 | Disruption of MKK3/MYC protein-protein interaction in human HCT-116 cells assessed as decrease in MYC level at 0.5 to 10 uM measured by western blot assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1505768 | Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assay | 2018 | Journal of medicinal chemistry, Aug-09, Volume: 61, Issue:15
| Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy. |
| AID1777439 | Inhibition of Renilla luciferase activity expressed in human HCT-116 cells assessed as decrease in luminescence at 10 uM measured after 12 hrs by luminescence assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1073763 | Selectivity ratio of IC50 for human GLP (734 to 1235) to IC50 for human N-terminal 600 residues-deleted DNMT1 | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1777418 | Disruption of interaction between human recombinant GST-tagged MKK3/VF-tagged MYC expressed in HEK293T cells measured after 2 hrs by TR-FRET assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1654634 | Substrate activity at aldehyde oxidase in human liver cytosol assessed as mono-oxide metabolite formation at 10 uM measured after 3 hrs by LC-MS analysis | 2020 | Journal of medicinal chemistry, 06-25, Volume: 63, Issue:12
| Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model. |
| AID736573 | Inhibition of human DNMT1 using AdoMet and poly dI-dC at 50 uM after 2 hrs by radioactive assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line. |
| AID1240596 | Inhibition of human His-DNMT1 using [methyl-3H]SAM as substrate after 2 hrs | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17
| Design and synthesis of new non nucleoside inhibitors of DNMT3A. |
| AID1654638 | Substrate activity at aldehyde oxidase in human liver cytosol assessed as mono-oxide metabolite formation at 10 uM measured after 3 hrs in presence of XO inhibitor allopurinol by UPLC/Q-TOF MS analysis | 2020 | Journal of medicinal chemistry, 06-25, Volume: 63, Issue:12
| Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model. |
| AID1777430 | Disruption of interaction between human recombinant GST-tagged MKK3/VF-tagged MYC expressed in HEK293T cells at 20 uM measured after 2 hrs by TR-FRET assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID736572 | Inhibition of human DNMT1 using AdoMet and poly dI-dC after 2 hrs by radioactive assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line. |
| AID1777436 | Inhibition of MKK3 in human HEK293T cells assessed as inhibition of p38 phosphorylation by western blot analysis | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1447861 | Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA duplex at 100 uM after 1 hr by scintillation counting method relative to control | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells. |
| AID1654636 | Substrate activity at aldehyde oxidase in human liver cytosol assessed as mono-oxide metabolite formation at 10 uM measured after 3 hrs in presence of AOX inhibitor raloxifene by UPLC/Q-TOF MS analysis | 2020 | Journal of medicinal chemistry, 06-25, Volume: 63, Issue:12
| Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model. |
| AID1505769 | Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assay | 2018 | Journal of medicinal chemistry, Aug-09, Volume: 61, Issue:15
| Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy. |
| AID1073771 | Inhibition of human N-terminal 600 residues-deleted DNMT1 using poly(dI-dC) as substrate in presence of AdoMet | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1505822 | Inhibition of human DNMT1 using hemimethylated DNA as substrate by radioactive methyl transfer assay | 2018 | Journal of medicinal chemistry, Aug-09, Volume: 61, Issue:15
| Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy. |
| AID1777441 | Inhibition of Renilla luciferase activity expressed in human MDA-MB-468 cells assessed as decrease in luminescence at 10 uM measured after 12 hrs by luminescence assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1505823 | Inhibition of G9a (unknown origin) | 2018 | Journal of medicinal chemistry, Aug-09, Volume: 61, Issue:15
| Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy. |
| AID1240603 | Antiproliferative activity against human HCT116 cells after 2 to 4 days by ATPlite 1step luminescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17
| Design and synthesis of new non nucleoside inhibitors of DNMT3A. |
| AID1447859 | Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex at CpG site at 10 uM after 1 hr by fluorescence assay relative to control | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells. |
| AID1073769 | Inhibition of human DNMT3A2/3L using unmethylated DNA as substrate in presence of [methyl-3H]-AdoMet | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1073757 | Cytotoxicity against human MDA-MB-231 cells after 48 hrs by trypan blue exclusion assay | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1777427 | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by Alamar blue assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID736574 | Induction of apoptosis in human U937 cells assessed as accumulation at pre-G1 phase after 30 hrs by FACS analysis | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line. |
| AID1240601 | Antiproliferative activity against human KG1 cells after 2 to 4 days by ATPlite 1step luminescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17
| Design and synthesis of new non nucleoside inhibitors of DNMT3A. |
| AID1777440 | Inhibition of cell migration in human HCT-116 cells at 0.75 to 3 uM by scratch wound healing assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1777423 | Disruption of MKK3/MYC protein-protein interaction in human HCT-116 cells assessed as decrease in PDL1 level at 0.5 to 10 uM measured by western blot assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1073759 | Cytotoxicity against human Raji cells after 48 hrs by trypan blue exclusion assay | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1777433 | Disruption of interaction between human recombinant GST-tagged MAX/VF-tagged MYC expressed in HEK293T cells at 50 uM incubated for 30 mins by GST pull-down assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1073764 | Inhibition of human GLP (734 to 1235) using histone as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by liquid scintillation counting analysis in presence of [methyl-3H]-AdoMet | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1777432 | Disruption of interaction between human recombinant GST-tagged MKK3/VF-tagged MYC expressed in HEK293T cells at 50 uM incubated for 30 mins by GST pull-down assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1452275 | Antiproliferative activity against human K562 cells after 72 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Jul-07, Volume: 134 | Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors. |
| AID1777438 | Disruption of MKK3/MYC protein-protein interaction in human MDA-MB-468 cells assessed as decrease in PDL1 level at 1 to 20 uM measured by western blot assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1447860 | Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA duplex at 32 uM after 1 hr by scintillation counting method relative to control | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells. |
| AID1664320 | Inhibition of human C-terminal DNMT3A (623 to 908 residues) using 5'-biotin labeled oligonucleotide as substrate measured after 1 hr | 2020 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 30, Issue:16
| Novel anticancer drug curaxin CBL0137 impairs DNA methylation by eukaryotic DNA methyltransferase Dnmt3a. |
| AID1073761 | Cytotoxicity against human U937 cells after 48 hrs by trypan blue exclusion assay | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1777435 | Disruption of interaction between human recombinant GST-tagged MKK3/His-tagged MYC HLH LZ domain measured after 2 hrs by TR-FRET assay | 2021 | Bioorganic & medicinal chemistry, 09-01, Volume: 45 | Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. |
| AID1199270 | Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biotinylated 45-bp unmethylated or hemimethylated oligonucleotide substrates and [3H]-AdoMet by liquid scinti | 2015 | Journal of medicinal chemistry, Mar-26, Volume: 58, Issue:6
| Targeting DNA methylation with small molecules: what's next? |
| AID1654635 | Substrate activity at aldehyde oxidase in human liver cytosol assessed as mono-oxide metabolite formation at 10 uM measured after 3 hrs by UPLC/Q-TOF MS analysis | 2020 | Journal of medicinal chemistry, 06-25, Volume: 63, Issue:12
| Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model. |
| AID1505821 | Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate by radioactive methyl transfer assay | 2018 | Journal of medicinal chemistry, Aug-09, Volume: 61, Issue:15
| Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy. |
| AID1073760 | Cytotoxicity against human PBMC after 48 hrs by trypan blue exclusion assay | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1240593 | Inhibition of human C-terminal DNMT3A after 1 hr by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17
| Design and synthesis of new non nucleoside inhibitors of DNMT3A. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346116 | Human DNA methyltransferase 1 (2.1.1.- Methyltransferases) | 2014 | Journal of medicinal chemistry, Feb-13, Volume: 57, Issue:3
| Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. |
| AID1802375 | DNA Methylation Assay from Article 10.1074/jbc.M113.480517: \\Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.\\ | 2013 | The Journal of biological chemistry, Aug-16, Volume: 288, Issue:33
| Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |