lovastatin has been researched along with Neuroblastoma in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Cibelli, A; Scemes, E; Spray, DC | 1 |
| Califano, A; Hirschhorn, T; Shimada, K; Small, JC; Stockwell, BR; Stokes, ME; Vasciaveo, A | 1 |
| Evangelopoulos, ME; Krüttgen, A; Weis, J; Wüller, S | 1 |
| Arnold, DE; Dimitroulakos, J; Gagne, C; McBurney, MW; Niknejad, N | 1 |
| Tuğlu, MI; Vural, K | 1 |
| Bianco, AM; Crovella, S; Girardelli, M; Marcuzzi, A; Monasta, L; Piscianz, E; Tricarico, PM; Vuch, J; Zanin, V | 1 |
| Andreatta, C; Cole, WC; Edwards-Prasad, J; Koustas, WT; Kumar, B; Prasad, KN | 1 |
| Guan, ZZ; Mousavi, M; Nordberg, A; Nordman, T; Olsson, JM; Shan, KR; Xiu, J; Yu, WF | 1 |
| Gilch, S; Kehler, C; Schätzl, HM | 1 |
| Amara, F; Arthur, G; Dibrov, A; He, Y; Kashour, T; Salins, P; Shawesh, S | 1 |
| Arias, C; Ferrera, P; Mercado-Gómez, O; Silva-Aguilar, M; Valverde, M | 1 |
| Maltese, WA | 1 |
| Augusti-Tocco, G; Bruscalupi, G; Castellano, F; Columba, S; Di Croce, L; Trentalance, A | 1 |
| Dimitroulakos, J; Yeger, H | 1 |
| Galli, C; Marangoni, F; Petroni, A; Risé, P; Visioli, F | 1 |
| Fisher, SK; Linseman, DA; McEwen, EL; Sorensen, SD | 1 |
| Becke, D; Bruchelt, G; Girgert, R; Schweizer, P; Vogt, Y | 1 |
| Haklai, R; Kloog, Y | 1 |
| Aprille, JR; Maltese, WA | 1 |
| Defendini, R; Donley, DK; Green, RA; Maltese, WA; Sheridan, KM | 1 |
| Maltese, WA; Sheridan, KM | 1 |
21 other study(ies) available for lovastatin and Neuroblastoma
| Article | Year |
|---|---|
Activity and Stability of Panx1 Channels in Astrocytes and Neuroblastoma Cells Are Enhanced by Cholesterol Depletion.
Topics: Adenosine Triphosphate; Anticholesteremic Agents; Astrocytes; Cholesterol; Connexins; Humans; Ion Channels; Lovastatin; Membrane Lipids; Nerve Tissue Proteins; Neuroblastoma; Protein Stability | 2022 |
Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Lovastatin; Methotrexate; N-Myc Proto-Oncogene Protein; Neuroblastoma; Protein Prenylation; Receptor, Transforming Growth Factor-beta Type II; RNA, Small Interfering; Signal Transduction; Triamterene | 2020 |
A role of nitric oxide in neurite outgrowth of neuroblastoma cells triggered by mevastatin or serum reduction.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Culture Media, Serum-Free; Enzyme Activation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Neurites; Neuroblastoma; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitroprusside; Proto-Oncogene Proteins c-akt | 2010 |
Lovastatin induces neuronal differentiation and apoptosis of embryonal carcinoma and neuroblastoma cells: enhanced differentiation and apoptosis in combination with dbcAMP.
Topics: Antineoplastic Agents; Apoptosis; Bucladesine; Carcinoma, Embryonal; Cell Differentiation; Cyclic AMP; Drug Synergism; Drug Therapy, Combination; Humans; Lovastatin; Neuroblastoma; Response Elements; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 2010 |
Neurotoxic effect of statins on mouse neuroblastoma NB2a cell line.
Topics: Animals; Atorvastatin; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Neurites; Neuroblastoma; Pyrroles | 2011 |
Lovastatin-induced apoptosis is modulated by geranylgeraniol in a neuroblastoma cell line.
Topics: Analysis of Variance; Apoptosis; Caspases; Cell Line, Tumor; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Neuroblastoma; Time Factors | 2012 |
Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects.
Topics: Animals; Anticholesteremic Agents; Cell Differentiation; Cell Survival; Culture Media; Cyclic AMP; Cysteine Endopeptidases; Lovastatin; Mevalonic Acid; Multienzyme Complexes; Nerve Degeneration; Neuroblastoma; Neurons; Pravastatin; Proteasome Endopeptidase Complex; Tumor Cells, Cultured | 2002 |
Lovastatin stimulates up-regulation of alpha7 nicotinic receptors in cultured neurons without cholesterol dependency, a mechanism involving production of the alpha-form of secreted amyloid precursor protein.
Topics: Amyloid beta-Protein Precursor; Animals; Blotting, Northern; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Cell Line, Tumor; Cholesterol; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isotopes; Lovastatin; Neuroblastoma; Neurons; Nicotine; Nicotinic Agonists; PC12 Cells; Protein Binding; Pyridines; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ubiquinone; Up-Regulation | 2005 |
The prion protein requires cholesterol for cell surface localization.
Topics: Animals; Caveolin 1; Cell Line; Cell Membrane; Cholesterol; Detergents; Glycosylphosphatidylinositols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Membrane Microdomains; Mice; Neuroblastoma; PrPC Proteins | 2006 |
Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signaling.
Topics: Amyloid beta-Peptides; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell Line, Tumor; Enzyme Activation; Humans; In Situ Nick-End Labeling; Indoles; Lovastatin; Lymphoid Enhancer-Binding Factor 1; Neuroblastoma; Neurons; Neuroprotective Agents; Peptide Fragments; Signal Transduction; Time Factors | 2007 |
Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anticholesteremic Agents; Cell Line, Tumor; Cell Survival; Cholesterol; Filipin; Humans; Lipid Peroxidation; Lovastatin; Mice; Neuroblastoma; Oxidative Stress; Reactive Oxygen Species | 2008 |
Induction of differentiation in murine neuroblastoma cells by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Topics: Acetylcholinesterase; Animals; Binding, Competitive; Cell Differentiation; Cell Line; DNA; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Naphthalenes; Neuroblastoma; Thymidine | 1984 |
Characterization of the response of growth and differentiation to lipoproteins and agents affecting cholesterol metabolism in murine neuroblastoma cells.
Topics: Animals; Cell Differentiation; Cell Division; Cholesterol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, HDL; Lovastatin; Mevalonic Acid; Mice; Neuroblastoma; Tumor Cells, Cultured | 1994 |
HMG-CoA reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: lovastatin specifically targets P-glycoprotein-expressing cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Bucladesine; DNA Primers; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Molecular Sequence Data; Neuroblastoma; Tretinoin; Tumor Cells, Cultured | 1996 |
Manipulation of the fate of long chain polyunsaturated fatty acids in cultured cells.
Topics: Arachidonic Acid; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line; Cholesterol; Enzyme Inhibitors; Ethanol; Fatty Acids, Unsaturated; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Linoleic Acid; Linoleic Acids; Liver Neoplasms; Lovastatin; Mevalonic Acid; Monocytes; Neuroblastoma; Simvastatin; Tumor Cells, Cultured | 1997 |
Cytoskeletal and phosphoinositide requirements for muscarinic receptor signaling to focal adhesion kinase and paxillin.
Topics: Actins; Androstadienes; Cell Adhesion; Cell Adhesion Molecules; Chromones; Cytochalasin D; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Humans; Lovastatin; Morpholines; Muscarinic Agonists; Neuroblastoma; Nucleic Acid Synthesis Inhibitors; Paxillin; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Muscarinic; Second Messenger Systems; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1998 |
Growth inhibition of neuroblastoma cells by lovastatin and L-ascorbic acid is based on different mechanisms.
Topics: Antineoplastic Agents; Ascorbic Acid; Cell Division; Dose-Response Relationship, Drug; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Neuroblastoma; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
Relationship among methylation, isoprenylation, and GTP binding in 21- to 23-kDa proteins of neuroblastoma.
Topics: Adenosine; Animals; Deoxyadenosines; Dimethyl Sulfoxide; GTP-Binding Proteins; Guanosine Triphosphate; Lovastatin; Membrane Proteins; Methylation; Mevalonic Acid; Mice; Molecular Weight; Neoplasm Proteins; Neuroblastoma; Protein Processing, Post-Translational; Thionucleosides; Tumor Cells, Cultured | 1991 |
Relation of mevalonate synthesis to mitochondrial ubiquinone content and respiratory function in cultured neuroblastoma cells.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Cholesterol; Lovastatin; Mevalonic Acid; Mice; Mitochondria; Naphthalenes; Neuroblastoma; Oxygen Consumption; Ubiquinone | 1985 |
Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Acetates; Animals; Cell Division; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Naphthalenes; Neuroblastoma; Ubiquinone | 1985 |
Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis.
Topics: Acetates; Acetylcholinesterase; Animals; Axons; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cholesterol; Cycloheximide; Glycoproteins; Growth Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Naphthalenes; Neuroblastoma; Terpenes | 1985 |