mebendazole has been researched along with Neuroblastoma in 1 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flubendazole was shown to exert anti-leukaemia and anti-myeloma activity through inhibition of microtubule function." | 5.42 | Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen. ( Abhari, BA; Agha, B; Cinatl, J; Dirks, WG; Fulda, S; Harter, PN; Langer, K; Löschmann, N; Michaelis, M; Mittelbronn, M; Riecken, K; Rothweiler, F; Spek, S; Starzetz, T; Voges, Y; Wass, MN; Westermann, F; Wiese, M; Zehner, R, 2015) |
| "Flubendazole was shown to exert anti-leukaemia and anti-myeloma activity through inhibition of microtubule function." | 1.42 | Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen. ( Abhari, BA; Agha, B; Cinatl, J; Dirks, WG; Fulda, S; Harter, PN; Langer, K; Löschmann, N; Michaelis, M; Mittelbronn, M; Riecken, K; Rothweiler, F; Spek, S; Starzetz, T; Voges, Y; Wass, MN; Westermann, F; Wiese, M; Zehner, R, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michaelis, M | 1 |
| Agha, B | 1 |
| Rothweiler, F | 1 |
| Löschmann, N | 1 |
| Voges, Y | 1 |
| Mittelbronn, M | 1 |
| Starzetz, T | 1 |
| Harter, PN | 1 |
| Abhari, BA | 1 |
| Fulda, S | 1 |
| Westermann, F | 1 |
| Riecken, K | 1 |
| Spek, S | 1 |
| Langer, K | 1 |
| Wiese, M | 1 |
| Dirks, WG | 1 |
| Zehner, R | 1 |
| Cinatl, J | 2 |
| Wass, MN | 1 |
1 other study available for mebendazole and Neuroblastoma
| Article | Year |
|---|---|
Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein | 2015 |