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sulfinpyrazone and Neuroblastoma

sulfinpyrazone has been researched along with Neuroblastoma in 1 studies

Sulfinpyrazone: A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"The neuroblastoma-like cell line N2A and the pheochromocytoma-like cell line PC12 excrete about 20-25% of the intracellular fluorescent Ca2+ indicator fura-2 during 10 min of incubation at 37 degrees C."3.67Inhibitors of membrane transport system for organic anions block fura-2 excretion from PC12 and N2A cells. ( Di Virgilio, F; Fasolato, C; Steinberg, TH, 1988)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di Virgilio, F1
Fasolato, C1
Steinberg, TH1

Other Studies

1 other study available for sulfinpyrazone and Neuroblastoma

ArticleYear
Inhibitors of membrane transport system for organic anions block fura-2 excretion from PC12 and N2A cells.
    The Biochemical journal, 1988, Dec-15, Volume: 256, Issue:3

    Topics: Animals; Benzofurans; Biological Transport; Calcium; Cell Line; Cell Membrane Permeability; Fluoresc

1988