| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346418 | Human OX2 receptor (Orexin receptors) | 1999 | British journal of pharmacology, Sep, Volume: 128, Issue:1
| Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR. |
| AID1346418 | Human OX2 receptor (Orexin receptors) | 2002 | FEBS letters, Aug-28, Volume: 526, Issue:1-3
| Orexin signaling in recombinant neuron-like cells. |
| AID1346418 | Human OX2 receptor (Orexin receptors) | 2003 | Journal of neurophysiology, Aug, Volume: 90, Issue:2
| Effects of orexin (hypocretin) on GIRK channels. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2001 | Psychopharmacology, Jan-01, Volume: 153, Issue:2
| Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity. |
| AID1346418 | Human OX2 receptor (Orexin receptors) | 1998 | Cell, Feb-20, Volume: 92, Issue:4
| Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 1999 | British journal of pharmacology, Sep, Volume: 128, Issue:1
| Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR. |
| AID1346418 | Human OX2 receptor (Orexin receptors) | 2003 | The Journal of pharmacology and experimental therapeutics, May, Volume: 305, Issue:2
| Distinct recognition of OX1 and OX2 receptors by orexin peptides. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 1998 | Cell, Feb-20, Volume: 92, Issue:4
| Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2003 | The Journal of pharmacology and experimental therapeutics, May, Volume: 305, Issue:2
| Distinct recognition of OX1 and OX2 receptors by orexin peptides. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2004 | American journal of physiology. Gastrointestinal and liver physiology, Dec, Volume: 287, Issue:6
| Orexin-A does not stimulate food intake in old rats. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2010 | British journal of pharmacology, Jan, Volume: 159, Issue:1
| Arachidonic acid release mediated by OX1 orexin receptors. |
| AID1346418 | Human OX2 receptor (Orexin receptors) | 2008 | Cellular signalling, Sep, Volume: 20, Issue:9
| The signalling profile of recombinant human orexin-2 receptor. |
| AID1346418 | Human OX2 receptor (Orexin receptors) | 2001 | Biochemical and biophysical research communications, Feb-02, Volume: 280, Issue:4
| Requirement of intact disulfide bonds in orexin-A-induced stimulation of gastric acid secretion that is mediated by OX1 receptor activation. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2002 | FEBS letters, Aug-28, Volume: 526, Issue:1-3
| Orexin signaling in recombinant neuron-like cells. |
| AID1346418 | Human OX2 receptor (Orexin receptors) | 2003 | Journal of pharmacological sciences, Jul, Volume: 92, Issue:3
| Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2001 | Neuroscience letters, Jun-15, Volume: 305, Issue:3
| High specificity of human orexin receptors for orexins over neuropeptide Y and other neuropeptides. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2004 | British journal of pharmacology, Jan, Volume: 141, Issue:2
| Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2008 | Cellular and molecular life sciences : CMLS, Jun, Volume: 65, Issue:12
| Multiple phospholipase activation by OX(1) orexin/hypocretin receptors. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2001 | Biochemical and biophysical research communications, Feb-02, Volume: 280, Issue:4
| Requirement of intact disulfide bonds in orexin-A-induced stimulation of gastric acid secretion that is mediated by OX1 receptor activation. |
| AID1346381 | Human OX1 receptor (Orexin receptors) | 2011 | Neuroscience letters, Apr-20, Volume: 494, Issue:1
| Agonist ligand discrimination by the two orexin receptors depends on the expression system. |
| AID256558 | Agonist selectivity for orexin receptor 1 versus orexin receptor 2 | 2003 | Bioorganic & medicinal chemistry letters, Jan-06, Volume: 13, Issue:1
| Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. |
| AID256557 | Agonist activity against human orexin 2 receptor; EC50; nM | 2003 | Bioorganic & medicinal chemistry letters, Jan-06, Volume: 13, Issue:1
| Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. |
| AID1878175 | Selectivity index, ratio of EC50 for agonist activity at OX1R (unknown origin) to EC50 for agonist activity at OX2R (unknown origin) | | | |
| AID256556 | Agonist activity against human orexin 1 receptor; EC50; nM | 2003 | Bioorganic & medicinal chemistry letters, Jan-06, Volume: 13, Issue:1
| Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. |
| AID1878169 | Agonist activity at OX1R (unknown origin) | | | |
| AID1878172 | Agonist activity at OX2R (unknown origin) | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |