pimagedine has been researched along with Neuroblastoma in 4 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Excerpt | Relevance | Reference |
---|---|---|
"However, in scrapie-infected N2a cells (ScN2a), the LPS-induced NO production was completely abolished." | 1.32 | Loss of lipopolysaccharide-induced nitric oxide production and inducible nitric oxide synthase expression in scrapie-infected N2a cells. ( Bedecs, K; Gyllberg, H; Lindegren, H; Ostlund, P, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Li, XH | 1 |
Xie, JZ | 1 |
Jiang, X | 1 |
Lv, BL | 1 |
Cheng, XS | 1 |
Du, LL | 1 |
Zhang, JY | 1 |
Wang, JZ | 1 |
Zhou, XW | 1 |
Lindegren, H | 1 |
Ostlund, P | 1 |
Gyllberg, H | 1 |
Bedecs, K | 1 |
de Arriba, SG | 1 |
Stuchbury, G | 1 |
Yarin, J | 1 |
Burnell, J | 1 |
Loske, C | 2 |
Münch, G | 2 |
Neumann, A | 1 |
Cunningham, AM | 1 |
Nichol, K | 1 |
Schinzel, R | 1 |
Riederer, P | 1 |
4 other studies available for pimagedine and Neuroblastoma
Article | Year |
---|---|
Methylglyoxal induces tau hyperphosphorylation via promoting AGEs formation.
Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Enzyme Activation; Glycation End Products, Advanced; G | 2012 |
Loss of lipopolysaccharide-induced nitric oxide production and inducible nitric oxide synthase expression in scrapie-infected N2a cells.
Topics: Animals; Blotting, Western; Cells, Cultured; Enzyme Inhibitors; Guanidines; Lipopolysaccharides; Mic | 2003 |
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers.
Topics: Adenosine Triphosphate; Analysis of Variance; Cell Line, Tumor; Dose-Response Relationship, Drug; En | 2007 |
Cytotoxicity of advanced glycation endproducts is mediated by oxidative stress.
Topics: Animals; Antioxidants; Cell Death; Cell Line; Cricetinae; Enzyme Inhibitors; Fibroblasts; Glycation | 1998 |