Page last updated: 2024-10-22

pimagedine and Neuroblastoma

pimagedine has been researched along with Neuroblastoma in 4 studies

pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"However, in scrapie-infected N2a cells (ScN2a), the LPS-induced NO production was completely abolished."1.32Loss of lipopolysaccharide-induced nitric oxide production and inducible nitric oxide synthase expression in scrapie-infected N2a cells. ( Bedecs, K; Gyllberg, H; Lindegren, H; Ostlund, P, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, XH1
Xie, JZ1
Jiang, X1
Lv, BL1
Cheng, XS1
Du, LL1
Zhang, JY1
Wang, JZ1
Zhou, XW1
Lindegren, H1
Ostlund, P1
Gyllberg, H1
Bedecs, K1
de Arriba, SG1
Stuchbury, G1
Yarin, J1
Burnell, J1
Loske, C2
Münch, G2
Neumann, A1
Cunningham, AM1
Nichol, K1
Schinzel, R1
Riederer, P1

Other Studies

4 other studies available for pimagedine and Neuroblastoma

ArticleYear
Methylglyoxal induces tau hyperphosphorylation via promoting AGEs formation.
    Neuromolecular medicine, 2012, Volume: 14, Issue:4

    Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Enzyme Activation; Glycation End Products, Advanced; G

2012
Loss of lipopolysaccharide-induced nitric oxide production and inducible nitric oxide synthase expression in scrapie-infected N2a cells.
    Journal of neuroscience research, 2003, Jan-15, Volume: 71, Issue:2

    Topics: Animals; Blotting, Western; Cells, Cultured; Enzyme Inhibitors; Guanidines; Lipopolysaccharides; Mic

2003
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers.
    Neurobiology of aging, 2007, Volume: 28, Issue:7

    Topics: Adenosine Triphosphate; Analysis of Variance; Cell Line, Tumor; Dose-Response Relationship, Drug; En

2007
Cytotoxicity of advanced glycation endproducts is mediated by oxidative stress.
    Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:8-9

    Topics: Animals; Antioxidants; Cell Death; Cell Line; Cricetinae; Enzyme Inhibitors; Fibroblasts; Glycation

1998