glycine has been researched along with Neuroblastoma in 49 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "After mouse neuroblastoma cells were cultured with [15N]glycine in Dulbecco's modified Eagle's medium for total four days, they gave significant amounts of 15N-atom% excess in phosphatidylserine, phosphatidylethanolamine, ethanolamine plasmalogen, phosphatidylcholine, sphingomyelin and ceramide." | 7.69 | Evidence for indirect utilization of glycine for production of N-bases of glycerophospholipids and sphingolipids in mouse neuroblastoma cells by using 15N-labeled glycine. ( Hara, A; Kurahashi, H; Taketomi, T; Uemura, K, 1995) |
| "Non-saturable penetration and the V and Km constants of saturable influx of leucine, lysine and glycine were always greater in cultured neuroblastoma (C1300) than in glioma (C6) cells." | 7.67 | Transport of leucine, lysine, glycine and aspartate in neuroblastoma C1300 and glioma C6 cells. ( Hannuniemi, R; Oja, OS; Oja, SS; Pajari-Backas, M, 1987) |
| "Human neuroblastoma SK-N-SH-SY5Y (5Y) and rat glioma (C6) cells were cultured with supplemental methionine, glycine, or serine for three to six days." | 7.66 | Effect of methionine, glycine and serine on serine hydroxymethyltransferase activity in rat glioma and human neuroblastoma cells. ( Kohl, RL; Perez-Polo, JR; Quay, WB, 1980) |
| " Our objective was to precisely assess changes in α-syn levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines following acute exposure to pesticides (rotenone, paraquat, maneb, and glyphosate) using Western blot and flow cytometry." | 3.79 | Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines. ( Andrieu, T; Baron, T; Bétemps, D; Chorfa, A; Hogeveen, K; Lazizzera, C; Morignat, E, 2013) |
| "Persistent infection of mouse neuroblastoma NB41A3 cells with yellow fever 17D virus generates viral variants which exhibit defective cell penetration, poor cell-to-cell spread, small plaque size and reduced growth efficiency, caused by substitution of glycine for aspartic acid or glutamic acid at positions 360 and 362 in the envelope protein." | 3.73 | Neuroblastoma cell-adapted yellow fever virus: mutagenesis of the E protein locus involved in persistent infection and its effects on virus penetration and spread. ( Chambers, TJ; Droll, DA; Nickells, M; Vlaycheva, L, 2005) |
| "After mouse neuroblastoma cells were cultured with [15N]glycine in Dulbecco's modified Eagle's medium for total four days, they gave significant amounts of 15N-atom% excess in phosphatidylserine, phosphatidylethanolamine, ethanolamine plasmalogen, phosphatidylcholine, sphingomyelin and ceramide." | 3.69 | Evidence for indirect utilization of glycine for production of N-bases of glycerophospholipids and sphingolipids in mouse neuroblastoma cells by using 15N-labeled glycine. ( Hara, A; Kurahashi, H; Taketomi, T; Uemura, K, 1995) |
| " MDA-MB-435 human breast carcinoma cells were transfected with a control expression vector (pCMVBamneo), the vector containing the wild type nm23-H1, or the nm23-H1 vector encoding mutations at the following amino acids: serine 44, a phosphorylation site; proline 96, the k-pn mutation in the Drosophila nm23 homolog that causes developmental defects; histidine 118, involved in Nm23's nucleoside diphosphate kinase activity; and serine 120, a site of mutation in human neuroblastomas and phosphorylation." | 3.69 | Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells. ( Freije, JM; MacDonald, NJ; Manrow, RE; Steeg, PS; Stracke, ML, 1996) |
| "The point mutation serine 120 to glycine in the human nucleoside diphosphate kinase A has been identified in several aggressive neuroblastomas (Chang, C." | 3.69 | A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding. ( Briand, G; Giartosio, A; Konrad, M; Lacombe, ML; Lascu, I; Sarger, C; Schaertl, S; Wang, C, 1997) |
| " In protein-depleted A/J mice (n = 340) bearing either an immunogenic (C1300) or poorly immunogenic (TBJ) neuroblastoma, arginine supplementation [1%] significantly augmented T lymphocyte responses (mitogenesis, interleukin-2 production) compared with both a glycine-supplemented and nonsupplemented group." | 3.67 | Arginine, protein malnutrition, and cancer. ( Daly, JM; Naji, A; Reynolds, JV; Thom, AK; Zhang, SM; Ziegler, MM, 1988) |
| "Non-saturable penetration and the V and Km constants of saturable influx of leucine, lysine and glycine were always greater in cultured neuroblastoma (C1300) than in glioma (C6) cells." | 3.67 | Transport of leucine, lysine, glycine and aspartate in neuroblastoma C1300 and glioma C6 cells. ( Hannuniemi, R; Oja, OS; Oja, SS; Pajari-Backas, M, 1987) |
| "Human neuroblastoma SK-N-SH-SY5Y (5Y) and rat glioma (C6) cells were cultured with supplemental methionine, glycine, or serine for three to six days." | 3.66 | Effect of methionine, glycine and serine on serine hydroxymethyltransferase activity in rat glioma and human neuroblastoma cells. ( Kohl, RL; Perez-Polo, JR; Quay, WB, 1980) |
| "Neuroblastoma is primarily an embryonal tumor of infancy." | 2.82 | Pre-conceptional and prenatal exposure to pesticides and pediatric neuroblastoma. A meta-analysis of nine studies. ( Feulefack, J; Khan, A; Sergi, CM, 2022) |
| " Activation of mGlu5 receptors by CHPG (1 mM) and 3HPG (50 microM) abolished the toxic effect produced by 3 microM MPP(+)." | 1.35 | Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells. ( Battistin, L; Benarese, M; Boroni, F; Lanzillotta, A; Pizzi, M; Sarnico, I; Sigala, S; Spano, P, 2008) |
| "The putative metastasis suppressor genes, NME1(nm23-1) and NME2(nm23-2), were examined in a model system we developed to approximate the dissemination of melanoma from a primary skin tumor." | 1.29 | Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials. ( Backer, JM; Hamby, CV; Mendola, CE; Potla, L; Stafford, G, 1995) |
| " This observation can be interpreted as indication that within this dosage range there is an absence of morphine-like subjective effects." | 1.28 | Analogs of the delta opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions. ( Anthony, E; Beardsley, PM; Chandrakumar, NS; Drury, B; Lopez, OT; Reichman, M; Savage, MA; Stapelfeld, A; Williamson, LN, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (14.29) | 18.7374 |
| 1990's | 13 (26.53) | 18.2507 |
| 2000's | 12 (24.49) | 29.6817 |
| 2010's | 9 (18.37) | 24.3611 |
| 2020's | 8 (16.33) | 2.80 |
| Authors | Studies |
|---|---|
| Li, T | 1 |
| Stayrook, SE | 1 |
| Tsutsui, Y | 1 |
| Zhang, J | 1 |
| Wang, Y | 1 |
| Li, H | 1 |
| Proffitt, A | 1 |
| Krimmer, SG | 1 |
| Ahmed, M | 1 |
| Belliveau, O | 1 |
| Walker, IX | 1 |
| Mudumbi, KC | 1 |
| Suzuki, Y | 1 |
| Lax, I | 1 |
| Alvarado, D | 1 |
| Lemmon, MA | 1 |
| Schlessinger, J | 1 |
| Klein, DE | 1 |
| Khan, A | 1 |
| Feulefack, J | 1 |
| Sergi, CM | 1 |
| Uchino, A | 1 |
| Irie, Y | 1 |
| Tsukano, C | 1 |
| Kawase, T | 1 |
| Hirose, K | 1 |
| Kageyama, Y | 1 |
| Tooyama, I | 1 |
| Yanagita, RC | 1 |
| Irie, K | 1 |
| Alptekin, A | 2 |
| Ye, B | 2 |
| Yu, Y | 2 |
| Poole, CJ | 1 |
| van Riggelen, J | 1 |
| Zha, Y | 2 |
| Ding, HF | 2 |
| Martínez, MA | 1 |
| Rodríguez, JL | 1 |
| Lopez-Torres, B | 1 |
| Martínez, M | 1 |
| Martínez-Larrañaga, MR | 1 |
| Maximiliano, JE | 1 |
| Anadón, A | 1 |
| Ares, I | 1 |
| Kowalczyk, JT | 1 |
| Wan, X | 1 |
| Hernandez, ER | 1 |
| Luo, R | 1 |
| Lyons, GC | 1 |
| Wilson, KM | 1 |
| Gallardo, DC | 1 |
| Isanogle, KA | 1 |
| Robinson, CM | 1 |
| Mendoza, A | 1 |
| Heske, CM | 1 |
| Chen, JQ | 1 |
| Luo, X | 1 |
| Kelly, AE | 1 |
| Difilippantinio, S | 1 |
| Robey, RW | 1 |
| Thomas, CJ | 1 |
| Sackett, DL | 1 |
| Morrison, DK | 1 |
| Randazzo, PA | 1 |
| Jenkins, LMM | 1 |
| Yohe, ME | 1 |
| Rhine, K | 1 |
| Makurath, MA | 1 |
| Liu, J | 1 |
| Skanchy, S | 1 |
| Lopez, C | 1 |
| Catalan, KF | 1 |
| Ma, Y | 1 |
| Fare, CM | 1 |
| Shorter, J | 1 |
| Ha, T | 1 |
| Chemla, YR | 1 |
| Myong, S | 1 |
| Arlt, B | 1 |
| Zasada, C | 1 |
| Baum, K | 1 |
| Wuenschel, J | 1 |
| Mastrobuoni, G | 1 |
| Lodrini, M | 1 |
| Astrahantseff, K | 1 |
| Winkler, A | 1 |
| Schulte, JH | 1 |
| Finkler, S | 1 |
| Forbes, M | 1 |
| Hundsdoerfer, P | 1 |
| Guergen, D | 1 |
| Hoffmann, J | 1 |
| Wolf, J | 1 |
| Eggert, A | 1 |
| Kempa, S | 1 |
| Deubzer, HE | 1 |
| Huang, H | 1 |
| Gont, A | 1 |
| Kee, L | 1 |
| Dries, R | 1 |
| Pfeifer, K | 1 |
| Sharma, B | 1 |
| Debruyne, DN | 1 |
| Harlow, M | 1 |
| Sengupta, S | 1 |
| Guan, J | 1 |
| Yeung, CM | 1 |
| Wang, W | 1 |
| Hallberg, B | 1 |
| Palmer, RH | 1 |
| Irwin, MS | 1 |
| George, RE | 1 |
| Sadek, B | 1 |
| Oz, M | 1 |
| Nurulain, SM | 1 |
| Jayaprakash, P | 1 |
| Latacz, G | 1 |
| Kieć-Kononowicz, K | 1 |
| Szymańska, E | 1 |
| Xiong, W | 1 |
| Wu, Y | 1 |
| Xian, W | 1 |
| Song, L | 1 |
| Hu, L | 1 |
| Pan, S | 1 |
| Liu, M | 1 |
| Yao, S | 1 |
| Pei, L | 1 |
| Shang, Y | 1 |
| Xia, Y | 1 |
| Ding, J | 1 |
| Thangaraju, M | 1 |
| Prasad, PD | 1 |
| Ding, ZC | 1 |
| Park, EJ | 1 |
| Choi, JH | 1 |
| Gao, B | 1 |
| Fiehn, O | 1 |
| Yan, C | 1 |
| Dong, Z | 1 |
| Garcia, AR | 1 |
| Arsenian-Henriksson, M | 1 |
| Lesage, S | 1 |
| Anheim, M | 1 |
| Letournel, F | 1 |
| Bousset, L | 1 |
| Honoré, A | 1 |
| Rozas, N | 1 |
| Pieri, L | 1 |
| Madiona, K | 1 |
| Dürr, A | 1 |
| Melki, R | 1 |
| Verny, C | 1 |
| Brice, A | 1 |
| Chorfa, A | 1 |
| Bétemps, D | 1 |
| Morignat, E | 1 |
| Lazizzera, C | 1 |
| Hogeveen, K | 1 |
| Andrieu, T | 1 |
| Baron, T | 1 |
| Andres, D | 1 |
| Keyser, BM | 1 |
| Petrali, J | 1 |
| Benton, B | 1 |
| Hubbard, KS | 1 |
| McNutt, PM | 1 |
| Ray, R | 1 |
| Perry, KW | 1 |
| Falcone, JF | 1 |
| Fell, MJ | 1 |
| Ryder, JW | 1 |
| Yu, H | 1 |
| Love, PL | 1 |
| Katner, J | 1 |
| Gordon, KD | 1 |
| Wade, MR | 1 |
| Man, T | 1 |
| Nomikos, GG | 1 |
| Phebus, LA | 1 |
| Cauvin, AJ | 1 |
| Johnson, KW | 1 |
| Jones, CK | 1 |
| Hoffmann, BJ | 1 |
| Sandusky, GE | 1 |
| Walter, MW | 1 |
| Porter, WJ | 1 |
| Yang, L | 1 |
| Merchant, KM | 1 |
| Shannon, HE | 1 |
| Svensson, KA | 1 |
| Barbara, G | 1 |
| Alloui, A | 1 |
| Nargeot, J | 1 |
| Lory, P | 1 |
| Eschalier, A | 1 |
| Bourinet, E | 1 |
| Chemin, J | 1 |
| Oddi, S | 1 |
| Dainese, E | 1 |
| Fezza, F | 1 |
| Lanuti, M | 1 |
| Barcaroli, D | 1 |
| De Laurenzi, V | 1 |
| Centonze, D | 1 |
| Maccarrone, M | 1 |
| Pizzi, M | 2 |
| Boroni, F | 2 |
| Bianchetti, A | 1 |
| Moraitis, C | 1 |
| Sarnico, I | 2 |
| Benarese, M | 2 |
| Goffi, F | 1 |
| Valerio, A | 1 |
| Spano, P | 2 |
| Holzmann, C | 1 |
| Krüger, R | 1 |
| Saecker, AM | 1 |
| Schmitt, I | 1 |
| Schöls, L | 1 |
| Berger, K | 1 |
| Riess, O | 1 |
| Florio, T | 1 |
| Paludi, D | 1 |
| Villa, V | 1 |
| Principe, DR | 1 |
| Corsaro, A | 1 |
| Millo, E | 1 |
| Damonte, G | 1 |
| D'Arrigo, C | 1 |
| Russo, C | 1 |
| Schettini, G | 1 |
| Aceto, A | 1 |
| Parsons, MJ | 1 |
| D'Souza, UM | 1 |
| Arranz, MJ | 1 |
| Kerwin, RW | 1 |
| Makoff, AJ | 1 |
| Merkler, DJ | 1 |
| Chew, GH | 1 |
| Gee, AJ | 1 |
| Merkler, KA | 1 |
| Sorondo, JP | 1 |
| Johnson, ME | 1 |
| Vlaycheva, L | 1 |
| Nickells, M | 1 |
| Droll, DA | 1 |
| Chambers, TJ | 1 |
| Guyon, A | 1 |
| Rovère, C | 1 |
| Cervantes, A | 1 |
| Allaeys, I | 1 |
| Nahon, JL | 1 |
| Ooe, H | 1 |
| Maita, C | 1 |
| Maita, H | 1 |
| Iguchi-Ariga, SM | 1 |
| Ariga, H | 1 |
| Sigala, S | 1 |
| Lanzillotta, A | 1 |
| Battistin, L | 1 |
| Kohl, RL | 1 |
| Perez-Polo, JR | 1 |
| Quay, WB | 1 |
| Kurahashi, H | 1 |
| Uemura, K | 1 |
| Hara, A | 1 |
| Taketomi, T | 1 |
| Hamby, CV | 1 |
| Mendola, CE | 1 |
| Potla, L | 1 |
| Stafford, G | 1 |
| Backer, JM | 1 |
| Ohkuma, S | 1 |
| Katsura, M | 1 |
| Chen, DZ | 1 |
| Chen, SH | 1 |
| Kuriyama, K | 1 |
| Buée, L | 1 |
| Ding, W | 1 |
| Delacourte, A | 1 |
| Fillit, H | 1 |
| Chang, CL | 1 |
| Strahler, JR | 1 |
| Thoraval, DH | 1 |
| Qian, MG | 1 |
| Hinderer, R | 1 |
| Hanash, SM | 1 |
| MacDonald, NJ | 1 |
| Freije, JM | 1 |
| Stracke, ML | 1 |
| Manrow, RE | 1 |
| Steeg, PS | 1 |
| Basavappa, S | 1 |
| Huang, CC | 1 |
| Mangel, AW | 1 |
| Lebedev, DV | 1 |
| Knauf, PA | 1 |
| Ellory, JC | 1 |
| Egorova, A | 1 |
| Hoshi, N | 1 |
| Knijnik, R | 1 |
| Shahidullah, M | 1 |
| Hashii, M | 1 |
| Noda, M | 1 |
| Higashida, H | 1 |
| Lascu, I | 1 |
| Schaertl, S | 1 |
| Wang, C | 1 |
| Sarger, C | 1 |
| Giartosio, A | 1 |
| Briand, G | 1 |
| Lacombe, ML | 1 |
| Konrad, M | 1 |
| Zaulyanov, LL | 1 |
| Green, PS | 1 |
| Simpkins, JW | 1 |
| Belachew, S | 1 |
| Malgrange, B | 1 |
| Rigo, JM | 1 |
| Rogister, B | 1 |
| Leprince, P | 1 |
| Hans, G | 1 |
| Nguyen, L | 1 |
| Moonen, G | 1 |
| Bi, G | 1 |
| Chen, YZ | 1 |
| Haber, B | 1 |
| Hutchison, HT | 1 |
| Archer, EG | 1 |
| Breakefield, XO | 1 |
| Sharata, MN | 1 |
| Skaper, SD | 1 |
| Seegmiller, JE | 1 |
| Chandrakumar, NS | 1 |
| Stapelfeld, A | 1 |
| Beardsley, PM | 1 |
| Lopez, OT | 1 |
| Drury, B | 1 |
| Anthony, E | 1 |
| Savage, MA | 1 |
| Williamson, LN | 1 |
| Reichman, M | 1 |
| Reynolds, JV | 2 |
| Daly, JM | 2 |
| Shou, J | 1 |
| Sigal, R | 1 |
| Ziegler, MM | 2 |
| Naji, A | 2 |
| Thom, AK | 1 |
| Zhang, SM | 1 |
| Hannuniemi, R | 1 |
| Pajari-Backas, M | 1 |
| Oja, OS | 1 |
| Oja, SS | 1 |
| Richelson, E | 1 |
| Thompson, EJ | 1 |
1 review available for glycine and Neuroblastoma
| Article | Year |
|---|---|
Pre-conceptional and prenatal exposure to pesticides and pediatric neuroblastoma. A meta-analysis of nine studies.
Topics: Adolescent; Adult; Child; Child, Preschool; Diazinon; Female; Glycine; Humans; Infant; Infant, Newbo | 2022 |
48 other studies available for glycine and Neuroblastoma
| Article | Year |
|---|---|
Structural basis for ligand reception by anaplastic lymphoma kinase.
Topics: Anaplastic Lymphoma Kinase; Animals; Binding Sites; Crystallography, X-Ray; Glycine; Humans; Infant; | 2021 |
Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Glycine; Humans; Neuroblastoma; Peptide Fragments | 2022 |
Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Carcinogenesis; Cell Cycle Checkpoints; Cell Line, Tumor; Cel | 2019 |
Use of human neuroblastoma SH-SY5Y cells to evaluate glyphosate-induced effects on oxidative stress, neuronal development and cell death signaling pathways.
Topics: Cell Death; Cell Line, Tumor; Cell Survival; Glycine; Glyphosate; Humans; Neuroblastoma; Oxidative S | 2020 |
Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma.
Topics: Apoptosis; Glycine; Humans; Neuroblastoma; Rhabdomyosarcoma; Spindle Apparatus; Sulfones | 2021 |
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.
Topics: Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Glycine; Humans; Inclusion Bodies; Mutation; | 2020 |
Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Topics: Animals; Cell Line, Tumor; Female; Gene Amplification; Glycine; Humans; Mice; N-Myc Proto-Oncogene P | 2021 |
Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration.
Topics: Amino Acid Sequence; Anaplastic Lymphoma Kinase; Animals; Base Sequence; Cell Line, Tumor; Cell Memb | 2021 |
Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Gly | 2017 |
DAPK1-ERK signal mediates oxygen glucose deprivation reperfusion induced apoptosis in mouse N2a cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cerebral Cortex; Cytarabine; Death-Associated Protein Kinases; | 2018 |
Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway.
Topics: Biosynthetic Pathways; Carbon; Cell Line, Tumor; Child; Glycine; Humans; N-Myc Proto-Oncogene Protei | 2019 |
Serine-Glycine-One-Carbon Metabolism: The Hidden Achilles Heel of
Topics: Carbon; Cell Line, Tumor; Glycine; Humans; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Prot | 2019 |
G51D α-synuclein mutation causes a novel parkinsonian-pyramidal syndrome.
Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Amyloid; Aspartic Acid; Blepharospasm; Caspase 3; D | 2013 |
Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines.
Topics: alpha-Synuclein; Cell Death; Cell Line, Tumor; Cell Survival; Glycine; Glyphosate; Humans; Insectici | 2013 |
Morphological and functional differentiation in BE(2)-M17 human neuroblastoma cells by treatment with Trans-retinoic acid.
Topics: Antineoplastic Agents; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calc | 2013 |
Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cell Line, Tumor; Cerebral Cortex; Corpus Striatum; Cycl | 2008 |
T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids.
Topics: Analgesics; Animals; Arachidonic Acids; Behavior, Animal; Calcium; Calcium Channel Blockers; Calcium | 2009 |
Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor.
Topics: Amino Acid Sequence; Cell Line, Tumor; Cell Membrane; Cholesterol; Consensus Sequence; Cyclic AMP; E | 2011 |
Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line.
Topics: Acetylcholine; Calcium Signaling; Cell Differentiation; Dose-Response Relationship, Drug; Excitatory | 2002 |
Polymorphisms of the alpha-synuclein promoter: expression analyses and association studies in Parkinson's disease.
Topics: Aged; alpha-Synuclein; Cell Culture Techniques; Cysteine; Enzyme-Linked Immunosorbent Assay; Female; | 2003 |
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line; Cell Survival; Circular Dichroism; Conserve | 2003 |
The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity.
Topics: Alanine; Cell Line, Tumor; Chloramphenicol O-Acetyltransferase; Cysteine; Genes, Reporter; Glycine; | 2004 |
Oleic acid derived metabolites in mouse neuroblastoma N18TG2 cells.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Culture Media; Enzyme Inhibitors; Fatty Acids, Mono | 2004 |
Neuroblastoma cell-adapted yellow fever virus: mutagenesis of the E protein locus involved in persistent infection and its effects on virus penetration and spread.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Cell Line, Tumor; Chlorocebus aethiops; Glycine; Mi | 2005 |
Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells.
Topics: Action Potentials; Animals; Benzylamines; Cadmium Chloride; Cells, Cultured; Chemokine CXCL12; Chemo | 2005 |
Specific cleavage of DJ-1 under an oxidative condition.
Topics: Blotting, Western; Cell Line, Tumor; Cysteine; Dose-Response Relationship, Drug; Gene Expression; Gl | 2006 |
Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Cell Death; Cell Line, Tumor; Dose-Response Relat | 2008 |
Effect of methionine, glycine and serine on serine hydroxymethyltransferase activity in rat glioma and human neuroblastoma cells.
Topics: Animals; Brain Neoplasms; Cell Line; Enzyme Activation; Glioma; Glycine; Glycine Hydroxymethyltransf | 1980 |
Evidence for indirect utilization of glycine for production of N-bases of glycerophospholipids and sphingolipids in mouse neuroblastoma cells by using 15N-labeled glycine.
Topics: Animals; Cell Line; Choline; Ethanolamine; Ethanolamines; Glycine; Mice; Neuroblastoma; Phosphatidic | 1995 |
Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Clone Cells; DNA Primers; Gene Expression; G | 1995 |
Presence of N-methyl-D-aspartate (NMDA) receptors in neuroblastoma x glioma hybrid NG108-15 cells-analysis using [45Ca2+]influx and [3H]MK-801 binding as functional measures.
Topics: Calcium Radioisotopes; Cations, Divalent; Dizocilpine Maleate; Glioma; Glutamates; Glutamic Acid; Gl | 1994 |
Binding of secreted human neuroblastoma proteoglycans to the Alzheimer's amyloid A4 peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal; Chondroitin Lyases; Chromatography | 1993 |
A nucleoside diphosphate kinase A (nm23-H1) serine 120-->glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction.
Topics: Base Sequence; Cross-Linking Reagents; DNA Primers; Enzyme Stability; Glutaral; Glycine; Hot Tempera | 1996 |
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
Topics: Alanine; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Division; Chemotaxis; Drosophila; Fema | 1996 |
Swelling-activated amino acid efflux in the human neuroblastoma cell line CHP-100.
Topics: Amino Acids; Glutamic Acid; Glycine; Humans; Hypotonic Solutions; Neuroblastoma; Neurons; Patch-Clam | 1996 |
Sulfhydryl modification inhibits K+ (M) current with kinetics close to acetylcholine in rodent NG108-15 cells.
Topics: Acetylcholine; Animals; Cysteine; Glioma; Glutathione; Glutathione Disulfide; Glycine; Hybrid Cells; | 1997 |
A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding.
Topics: Antigens, Neoplasm; Chromatography, Gel; Circular Dichroism; Glycine; Humans; Kinetics; Molecular We | 1997 |
Glutamate receptor requirement for neuronal death from anoxia-reoxygenation: an in Vitro model for assessment of the neuroprotective effects of estrogens.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; alpha-Cyclodextrins; Animals; beta-Cyclodextrins; Cell Death; Cel | 1999 |
Glycine triggers an intracellular calcium influx in oligodendrocyte progenitor cells which is mediated by the activation of both the ionotropic glycine receptor and Na+-dependent transporters.
Topics: Amino Acid Transport Systems, Neutral; Animals; Bicuculline; Biological Transport; Calcium; Calcium | 2000 |
[The rapid effects of steroids on glycine uptake in neuroblastoma cell strain SK-N-SH cells].
Topics: Corticosterone; Dexamethasone; Glycine; Humans; Neuroblastoma; Progesterone; Tumor Cells, Cultured | 1999 |
Uptake of neurotransmitters and precursors by clonal cell lines of neural origin.
Topics: Amino Acids; Aminooxyacetic Acid; Aspartic Acid; Astrocytoma; Biogenic Amines; Cell Line; Cell Membr | 1976 |
Transport of tyrosine, phenylalanine, tryptophan and glycine in neuroblastoma clones.
Topics: Amino Acids; Biological Transport; Clone Cells; Dinitrophenols; Glycine; Kinetics; Neuroblastoma; Ph | 1977 |
Increased concentrations of glycine in hypoxanthine-guanine phosphoribosyltransferase-deficient mouse neuroblastoma cells.
Topics: Adenine Phosphoribosyltransferase; Animals; Cells, Cultured; Glutamates; Glycine; Hypoxanthine Phosp | 1976 |
Analogs of the delta opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions.
Topics: Amides; Amino Acid Sequence; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; G | 1992 |
Immunologic effects of arginine supplementation in tumor-bearing and non-tumor-bearing hosts.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Diet; Dose-Response Relationship, Drug; Glycine; Kille | 1990 |
Arginine, protein malnutrition, and cancer.
Topics: Animals; Arginine; Body Weight; Diet; Glycine; Immune System; Lymphocyte Activation; Lymphocyte Cult | 1988 |
Transport of leucine, lysine, glycine and aspartate in neuroblastoma C1300 and glioma C6 cells.
Topics: Animals; Aspartic Acid; Cell Line, Transformed; Glioma; Glycine; Humans; Leucine; Lysine; Neuroblast | 1987 |
Transport of neurotransmitter precursors into cultured cells.
Topics: Acetylcholine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Catecholamines; Cell Lin | 1973 |