triiodothyronine has been researched along with Neuroblastoma in 33 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of triiodothyronine (T3) on the differentiation of cultured neuroblastoma (NB) cells was studied after 9 days of treatment with a dose of 10(-4) M/10(6) cells per day." | 7.68 | [In vitro and in vivo effect of thyroid hormones on the growth of neuroblastoma cells. I. The effect of triiodothyronine in vitro]. ( Baum, RP; Busse, E; Hör, G; Kornhuber, B; Rohrbach, E, 1990) |
| "We used the patch-clamp technique to analyze T3 and T4 modulation of nicotine (NIC)-mediated current in SH-SY5Y neuroblastoma cells." | 3.96 | Thyroid hormones reduce nicotinic receptor mediated currents in SH-SY5Y neuroblastoma cells. ( Puia, G; Ravazzini, F, 2020) |
| "The effects of the thyroid hormone triiodothyronine (T3), nerve growth factor (NGF) and stress (exposure to heat or aluminum sulfate) on growth, development and ageing of human neuroblastoma cells were studied in vitro." | 3.68 | Alterations in the growth and protein content of human neuroblastoma cells in vitro induced by thyroid hormones, stress and ageing. ( Goya, L; Isaeff, M; Timiras, PS, 1993) |
| "Nuclear receptors for the thyroid hormone triiodothyronine (T3) have been identified in vivo in brain tissues and in vitro in mouse and rat neuroblastoma and glioma cells." | 3.68 | Characterization of nuclear T3 receptors in human neuroblastoma cells SH-SY5Y: effect of differentiation with sodium butyrate and nerve growth factor. ( Goya, L; Timiras, PS, 1991) |
| "The effect of triiodothyronine (T3) on the differentiation of cultured neuroblastoma (NB) cells was studied after 9 days of treatment with a dose of 10(-4) M/10(6) cells per day." | 3.68 | [In vitro and in vivo effect of thyroid hormones on the growth of neuroblastoma cells. I. The effect of triiodothyronine in vitro]. ( Baum, RP; Busse, E; Hör, G; Kornhuber, B; Rohrbach, E, 1990) |
| "The uptake of 3,5,3'-triiodothyronine (T3) and thyroxine (T4) was studied in human glioma cells (Hs 683) and compared with that in several other neural cell lines." | 3.68 | Thyroid hormone transport in a human glioma cell line. ( Goncalves, E; Lakshmanan, M; Pontecorvi, A; Robbins, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (27.27) | 18.7374 |
| 1990's | 16 (48.48) | 18.2507 |
| 2000's | 6 (18.18) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Puia, G | 1 |
| Ravazzini, F | 1 |
| Gil-Ibáñez, P | 1 |
| Belinchón, MM | 1 |
| Morte, B | 1 |
| Obregón, MJ | 1 |
| Bernal, J | 1 |
| Cuesta, A | 1 |
| Zambrano, A | 1 |
| López, E | 1 |
| Pascual, A | 3 |
| Garcia-Silva, S | 2 |
| Perez-Juste, G | 2 |
| Aranda, A | 3 |
| Engelhard, A | 1 |
| Christiano, AM | 1 |
| Quirin-Stricker, C | 1 |
| Nappey, V | 1 |
| Simoni, P | 1 |
| Toussaint, JL | 1 |
| Schmitt, M | 1 |
| Feng, P | 1 |
| Li, QL | 1 |
| Satoh, T | 1 |
| Wilber, JF | 1 |
| Isaeff, M | 1 |
| Goya, L | 2 |
| Timiras, PS | 3 |
| Puymirat, J | 2 |
| Etongue-Mayer, P | 1 |
| Dussault, JH | 1 |
| Suter-Crazzolara, C | 1 |
| Unsicker, K | 1 |
| Barakat-Walter, I | 1 |
| Riederer, BM | 1 |
| Latasa, MJ | 1 |
| Belandia, B | 1 |
| Hahn, CG | 1 |
| Pawlyk, AC | 1 |
| Whybrow, PC | 1 |
| Tejani-Butt, SM | 1 |
| Chambery, D | 1 |
| De Galle, B | 1 |
| Ehrenborg, E | 1 |
| Babajko, S | 1 |
| Benvenga, S | 1 |
| Lakshmanan, M | 6 |
| Trimarchi, F | 1 |
| Kragie, L | 1 |
| Doyle, D | 1 |
| Goncalves, E | 5 |
| Pontecorvi, A | 2 |
| Robbins, J | 5 |
| Busse, E | 1 |
| Baum, RP | 1 |
| Rohrbach, E | 1 |
| Hör, G | 1 |
| Kornhuber, B | 1 |
| Cahnmann, HJ | 1 |
| Lessly, G | 1 |
| Foti, D | 1 |
| Safaei, R | 1 |
| Walz, MA | 1 |
| Howlett, AC | 2 |
| St Germain, DL | 2 |
| Watz, MA | 1 |
| Holt, IL | 1 |
| Chacon, M | 1 |
| Max, SR | 1 |
| Kirshner, JA | 1 |
| Tildon, JT | 1 |
| Ortiz-Caro, J | 1 |
| Yusta, B | 1 |
| Montiel, F | 1 |
| Villa, A | 1 |
| Gjessing, LR | 1 |
| Nishimura, T | 1 |
| Borud, O | 1 |
33 other studies available for triiodothyronine and Neuroblastoma
| Article | Year |
|---|---|
Thyroid hormones reduce nicotinic receptor mediated currents in SH-SY5Y neuroblastoma cells.
Topics: Cell Line, Tumor; Humans; Inhibitory Concentration 50; Neuroblastoma; Nicotine; Nicotinic Agonists; | 2020 |
Is the Intrinsic Genomic Activity of Thyroxine Relevant In Vivo? Effects on Gene Expression in Primary Cerebrocortical and Neuroblastoma Cells.
Topics: Animals; Astrocytes; Avian Proteins; Cell Line; Cells, Cultured; Cerebral Cortex; Chickens; Embryo, | 2017 |
Thyroid hormones reverse the UV-induced repression of APP in neuroblastoma cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line, Tumor; | 2009 |
Cell cycle control by the thyroid hormone in neuroblastoma cells.
Topics: Blotting, Western; Cell Cycle; Cell Differentiation; Cell Division; Down-Regulation; Genes, bcl-1; G | 2002 |
The hairless promoter is differentially regulated by thyroid hormone in keratinocytes and neuroblastoma cells.
Topics: Animals; Base Sequence; Cell Line; Cell Line, Tumor; DNA; Gene Expression Regulation; Genes, Reporte | 2004 |
Trans-activation by thyroid hormone receptors of the 5' flanking region of the human ChAT gene.
Topics: Amino Acid Sequence; Animals; Base Sequence; Breast Neoplasms; Cells, Cultured; Chlorocebus aethiops | 1994 |
Ligand (T3) dependent and independent effects of thyroid hormone receptors upon human TRH gene transcription in neuroblastoma cells.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; Gene Expression; Gene Expression Regulation, Neopl | 1994 |
Alterations in the growth and protein content of human neuroblastoma cells in vitro induced by thyroid hormones, stress and ageing.
Topics: Aging; Alum Compounds; Brain; Cell Differentiation; Cell Division; Cellular Senescence; DNA, Neoplas | 1993 |
Thyroid hormones stabilize acetylcholinesterase mRNA in neuro-2A cells that overexpress the beta 1 thyroid receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine | 1995 |
GDNF mRNA levels are induced by FGF-2 in rat C6 glioblastoma cells.
Topics: Animals; Astrocytes; Brain Neoplasms; Cell Division; Colforsin; Dexamethasone; Fibroblast Growth Fac | 1996 |
Triiodothyronine and nerve growth factor are required to induce cytoplasmic dynein expression in rat dorsal root ganglion cultures.
Topics: Animals; Cells, Cultured; Cytoplasm; Dyneins; Ganglia, Spinal; Microtubule Proteins; Microtubule-Ass | 1996 |
Thyroid hormone receptors are necessary but not sufficient for transcription.
Topics: Animals; Gene Expression Regulation; Glioma; Muscles; Neuroblastoma; Rats; Receptors, Adrenergic, be | 1996 |
Thyroid hormones regulate beta-amyloid gene splicing and protein secretion in neuroblastoma cells.
Topics: Alternative Splicing; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Culture Media; | 1998 |
Differential expression of thyroid hormone receptor isoforms by thyroid hormone and lithium in rat GH3 and B103 cells.
Topics: Adenoma; Animals; Gene Expression; Lithium; Neuroblastoma; Pituitary Neoplasms; Protein Isoforms; Ra | 1999 |
An element in the region responsible for premature termination of transcription mediates repression of c-myc gene expression by thyroid hormone in neuroblastoma cells.
Topics: Animals; Base Sequence; Cell Differentiation; Gene Expression Regulation, Neoplastic; Genes, myc; Hu | 2000 |
Multi-hormonal regulation of IGFBP-6 expression in human neuroblastoma cells.
Topics: Antineoplastic Agents; Base Sequence; Blotting, Northern; Blotting, Western; Carcinogens; Cell Divis | 2000 |
Carnitine is a naturally occurring inhibitor of thyroid hormone nuclear uptake.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Carnitine; Cell Line | 2000 |
Benzodiazepines inhibit temperature-dependent L-[125I]triiodothyronine accumulation into human liver, human neuroblast, and rat pituitary cell lines.
Topics: Adenoma; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Cell Line; Convulsants; D | 1992 |
Characterization of nuclear T3 receptors in human neuroblastoma cells SH-SY5Y: effect of differentiation with sodium butyrate and nerve growth factor.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Nucleus; Down-Regulation; Humans; Nerve Growth F | 1991 |
Differential effect of a new thyromimetic on triiodothyronine transport into myoblasts and hepatoma and neuroblastoma cells.
Topics: Animals; Biological Transport; Humans; Kinetics; Liver Neoplasms, Experimental; Mice; Muscles; Neuro | 1992 |
[In vitro and in vivo effect of thyroid hormones on the growth of neuroblastoma cells. I. The effect of triiodothyronine in vitro].
Topics: Adenosine Triphosphate; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic GMP; Guanosine Triphosph | 1990 |
High-affinity binding of thyroid hormones to neuroblastoma plasma membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Line; Cell Membrane; Hydrogen-Ion Concentration; | 1990 |
Thyroid hormone transport in a human glioma cell line.
Topics: Aminoisobutyric Acids; Antimycin A; Binding, Competitive; Biological Transport; Cadaverine; Cell Mem | 1990 |
The transport of thyroxine into mouse neuroblastoma cells, NB41A3: the effect of L-system amino acids.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Antimycin A; Binding, Competitive; Biological Transport | 1990 |
Thyroid hormone binding and regulation of adrenergic enzymes in two neuroblastoma cell lines.
Topics: Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Cell Nucleus; Culture Media; DNA, | 1985 |
Triiodothyronine transport into differentiated and undifferentiated mouse neuroblastoma cells (NB41A3).
Topics: Adenosine Triphosphate; Animals; Antimycin A; Biological Transport; Butyrates; Butyric Acid; Cadaver | 1989 |
Thyroid effects on adenosine 3',5'-monophosphate levels and adenylate cyclase in cultured neuroblastoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Astrocytoma; Cell Line; Colforsin; Cyclic AMP; Glioma; Guan | 1987 |
Regulatory effect of lithium on thyroxine metabolism in murine neural and anterior pituitary tissue.
Topics: Animals; Cell Line; Cerebral Cortex; Chlorides; Iodide Peroxidase; Kidney; Kinetics; Lithium; Lithiu | 1987 |
Cyclic nucleotide phosphodiesterase isozymes in neuroblastoma cells.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Calcimycin; Calcium; Calmodulin; Cell Line; Clo | 1987 |
Hormonal control of a low Km (type II) iodothyronine 5'-deiodinase in cultured NB41A3 mouse neuroblastoma cells.
Topics: Animals; Cell Line; Dexamethasone; Dithiothreitol; Epinephrine; Insulin; Iodide Peroxidase; Kinetics | 1986 |
Thyroid hormone actions on a cholinergic neuroblastoma cell line (S-20Y).
Topics: Animals; Cell Division; Cell Line; Choline O-Acetyltransferase; Iodide Peroxidase; Neuroblastoma; Re | 1986 |
Identification and characterization of L-triiodothyronine receptors in cells of glial and neuronal origin.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Glioma; Kinetics; Mice; Neuroblastoma; Ne | 1986 |
Studies on urinary phenolic compounds in man. I. Excretion of p-hydroxy-mandelic acid by man.
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography; Disulfiram; Humans; In Vitro Techniques; Mande | 1965 |