Page last updated: 2024-10-30

lamotrigine and Neuroblastoma

lamotrigine has been researched along with Neuroblastoma in 2 studies

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" To characterize further the mechanism of action of lamotrigine, we have investigated the effects of this drug together with the anticonvulsant drugs phenytoin and carbamazepine on voltage-sensitive sodium channels present in N4TG1 mouse neuroblastoma clonal cells."7.68Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells. ( Cooper, BR; Lang, DG; Wang, CM, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Kakumoto, M1
Shimokawa, K1
Ueshima, S1
Hira, D1
Okano, T1
Lang, DG1
Wang, CM1
Cooper, BR1

Other Studies

2 other studies available for lamotrigine and Neuroblastoma

ArticleYear
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
    Biochemical and biophysical research communications, 2021, 05-21, Volume: 554

    Topics: Anticonvulsants; Carbamazepine; Cell Line, Tumor; Cell Proliferation; Child; Epilepsy; Female; Human

2021
Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Lamotrigine; Mice; Neurob

1993