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hexamethylene bisacetamide and Neuroblastoma

hexamethylene bisacetamide has been researched along with Neuroblastoma in 5 studies

N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"The goal of the present work was to examine whether hexamethylene bisacetamide (HMBA) and cyclosporin A affect the recovery of herpes simplex virus type 2 (HSV-2) from an in vitro model of HSV-2 latency in human neuroblastoma cell line IMR-32."7.68Effect of hexamethylene bisacetamide and cyclosporin A on recovery of herpes simplex virus type 2 from the in vitro model of latency in a human neuroblastoma cell line. ( Furumoto, N; Iga, H; Kondo, Y; Sato, M; Yanagawa, T; Yoshida, H; Yura, Y, 1990)
"A basic nuclear protein with properties similar to lysine-rich histones accumulates during differentiation in vitro of C1300 murine neuroblastoma cells (clone Neuro-2a) induced by either n-butyrate, dimethyl sulfoxide, hexamethylene bisacetamide or 1,6-dibutyryl-adenosine 3',5'-monophosphate."3.66Accumulation of histone H1(0) during chemically induced differentiation of murine neuroblastoma cells. ( Adolf, GR; Pieler, C; Swetly, P, 1981)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Turano, M1
Napolitano, G1
Dulac, C1
Majello, B1
Bensaude, O1
Lania, L1
Pieler, C1
Adolf, GR1
Swetly, P1
Palfrey, C1
Kimhi, Y1
Littauer, UZ1
Kondo, Y1
Yura, Y1
Iga, H1
Yanagawa, T1
Yoshida, H1
Furumoto, N1
Sato, M1
Baumgold, J1
Spector, I1

Other Studies

5 other studies available for hexamethylene bisacetamide and Neuroblastoma

ArticleYear
Increased HEXIM1 expression during erythroleukemia and neuroblastoma cell differentiation.
    Journal of cellular physiology, 2006, Volume: 206, Issue:3

    Topics: Acetamides; Animals; Cell Differentiation; Cell Line, Tumor; Dimethyl Sulfoxide; Gene Expression Reg

2006
Accumulation of histone H1(0) during chemically induced differentiation of murine neuroblastoma cells.
    European journal of biochemistry, 1981, Volume: 115, Issue:2

    Topics: Acetamides; Animals; Bucladesine; Butyrates; Cell Differentiation; Cell Line; Clone Cells; Diamines;

1981
Induction of differentiation in mouse neuroblastoma cells by hexamethylene bisacetamide.
    Biochemical and biophysical research communications, 1977, Jun-06, Volume: 76, Issue:3

    Topics: Acetamides; Acetylcholinesterase; Biological Transport; Cell Differentiation; Cell Division; Cell Li

1977
Effect of hexamethylene bisacetamide and cyclosporin A on recovery of herpes simplex virus type 2 from the in vitro model of latency in a human neuroblastoma cell line.
    Cancer research, 1990, Dec-15, Volume: 50, Issue:24

    Topics: Acetamides; Cell Line; Cyclosporins; DNA, Viral; Humans; Kinetics; Neuroblastoma; Restriction Mappin

1990
Development of sodium channel protein during chemically induced differentiation of neuroblastoma cells.
    Journal of neurochemistry, 1987, Volume: 48, Issue:4

    Topics: Acetamides; Animals; Batrachotoxins; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Ion Channe

1987