ketamine has been researched along with Neuroblastoma in 12 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketamine is a dissociative anaesthetic used to induce general anaesthesia in humans and laboratory animals." | 1.91 | The effects of ketamine on viability, primary DNA damage, and oxidative stress parameters in HepG2 and SH-SY5Y cells. ( Canjuga, I; Češi, M; Jurič, A; Karačonji, IB; Katalinić, M; Lovaković, BT; Neuberg, M; Pizent, A; Rašić, D; Rešić, A; Vrdoljak, AL; Zandona, A, 2023) |
| "Ketamine is a widely used intravenous anesthetic; however, basic and clinical studies have demonstrated that prolonged exposure can cause irreversible injury to the immature human brain." | 1.56 | Yes‑associated protein protects and rescues SH‑SY5Y cells from ketamine‑induced apoptosis. ( Chen, Y; Ke, Z; Li, J; Li, Y; Wang, J; Wang, Y; Wei, L; Xuan, W; Yang, Z, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, R | 1 |
| Wang, X | 5 |
| Xie, Z | 1 |
| Cao, T | 1 |
| Jiang, S | 1 |
| Huang, L | 3 |
| Jurič, A | 1 |
| Lovaković, BT | 1 |
| Zandona, A | 1 |
| Rašić, D | 1 |
| Češi, M | 1 |
| Pizent, A | 1 |
| Neuberg, M | 1 |
| Canjuga, I | 1 |
| Katalinić, M | 1 |
| Vrdoljak, AL | 1 |
| Rešić, A | 1 |
| Karačonji, IB | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 7 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
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| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
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| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
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| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
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| D'Urzo, AD | 1 |
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| Diskin, SJ | 1 |
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| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 8 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
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| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
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| Rigol, M | 1 |
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| Villena-Gutierrez, R | 1 |
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| Cussó, L | 1 |
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| Li, J | 8 |
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| Liu, Y | 7 |
| Song, J | 1 |
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| Choi, GH | 1 |
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| Yu, X | 2 |
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| Hayton, TW | 1 |
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| Guo, W | 1 |
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| Chen, D | 5 |
| Luo, K | 1 |
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1 review available for ketamine and Neuroblastoma
1 trial available for ketamine and Neuroblastoma
11 other studies available for ketamine and Neuroblastoma
| Article | Year |
|---|---|
Lipoxin A4 methyl ester attenuated ketamine-induced neurotoxicity in SH-SY5Y cells via regulating leptin pathway.
Topics: Humans; Ketamine; Leptin; Lipoxins; Neuroblastoma | 2023 |
The effects of ketamine on viability, primary DNA damage, and oxidative stress parameters in HepG2 and SH-SY5Y cells.
Topics: Animals; Antioxidants; Catalase; Cell Line, Tumor; DNA Damage; Glutathione; Humans; Ketamine; Neurob | 2023 |
Yes‑associated protein protects and rescues SH‑SY5Y cells from ketamine‑induced apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Re | 2020 |
[Treatment of extreme tumour pain with morphine and s-ketamine A case report of an 11-year old girl].
Topics: Analgesics; Analgesics, Opioid; Carboplatin; Child; Dose-Response Relationship, Drug; Drug Therapy, | 2005 |
Intravenous ketamine infusion as an adjuvant to morphine in a 2-year-old with severe cancer pain from metastatic neuroblastoma.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Child, Preschool; Codeine; Drug | 2004 |
Ketamine use for reduction of opioid tolerance in a 5-year-old girl with end-stage abdominal neuroblastoma.
Topics: Abdominal Neoplasms; Abdominal Pain; Analgesics, Opioid; Anesthetics, Dissociative; Child, Preschool | 2005 |
Activation of N-methyl-D-aspartate receptor attenuates acute responsiveness of delta-opioid receptors.
Topics: Analgesics; Animals; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Enkephalin, D-Peni | 1997 |
The inhibition of human neuronal K+ currents by general anesthetic agents is altered by extracellular K.
Topics: Anesthetics, General; Etomidate; Humans; Ketamine; Membrane Potentials; Neuroblastoma; Neurons; Pota | 1998 |
Physiological and pharmacological properties of 5-HT3 receptors--a patch clamp-study.
Topics: Action Potentials; Animals; Cocaine; Ganglia; Guinea Pigs; Imidazoles; Ion Channels; Ketamine; Metoc | 1991 |
Ketamine anaesthesia for radiotherapy in small children.
Topics: Anesthesia, General; Anesthetics; Atropine; Blood Platelets; Body Weight; Child, Preschool; Cyclohex | 1972 |
The use of ketamine hydrochloride anaesthesia for radiotherapy in young children.
Topics: Anesthesia, General; Child, Preschool; Female; Hemangioma; Humans; Immobilization; Infant; Injection | 1973 |