Page last updated: 2024-12-11

dihydrohonokiol

Cross-References

ID SourceID
PubMed CID9816843
CHEMBL ID330311
SCHEMBL ID7785437
MeSH IDM0375930

Synonyms (7)

Synonym
CHEMBL330311
SCHEMBL7785437
3'-allyl-5-propyl-biphenyl-2,4'-diol
IBKNHHZQPPUDQJ-UHFFFAOYSA-N
EX-A6652
219565-74-9
dihydrohonokiol
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID196553Neurite length after administration (1 uM) in rat cortical neurons2004Bioorganic & medicinal chemistry letters, May-17, Volume: 14, Issue:10
Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan.
AID638015Neuroprotective activity in human SH-SY5Y cells assessed as inhibition of MPP+-induced cell death after 24 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
An expedient synthesis of honokiol and its analogues as potential neuropreventive agents.
AID196552Neurite length after administration (0.1 uM) in rat cortical neurons2004Bioorganic & medicinal chemistry letters, May-17, Volume: 14, Issue:10
Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan.
AID638016Neuroprotective activity in MPP+-stimulated human SH-SY5Y cells assessed as cell survival at 30 uM measured 24 hrs after MPP+-challenge by MTT assay2012Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
An expedient synthesis of honokiol and its analogues as potential neuropreventive agents.
AID637948Neuroprotective activity in human SH-SY5Y cells assessed as inhibition of CHP and TBHP-induced cell death at 10 uM incubated for 30 mins prior to challenge measured after 3 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Jan-01, Volume: 22, Issue:1
An expedient synthesis of honokiol and its analogues as potential neuropreventive agents.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.05

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index27.05 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index39.02 (26.88)
Search Engine Supply Index3.05 (0.95)

This Compound (27.05)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
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