ha 1004 has been researched along with Neuroblastoma in 6 studies
N-(2-guanidinoethyl)-5-isoquinolinesulfonamide: structure given in first source
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "SH-SY-5Y human neuroblastoma cells rapidly elaborated an extensive network of neuritic processes following treatment with staurosporine, an inhibitor of protein kinase C." | 7.68 | Staurosporine-induced morphological differentiation of human neuroblastoma cells. ( Beermann, ML; Shea, TB, 1991) |
| "SH-SY-5Y human neuroblastoma cells rapidly elaborated an extensive network of neuritic processes following treatment with staurosporine, an inhibitor of protein kinase C." | 3.68 | Staurosporine-induced morphological differentiation of human neuroblastoma cells. ( Beermann, ML; Shea, TB, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Miñana, MD | 3 |
| Felipo, V | 3 |
| Grisolía, S | 3 |
| Romero, FJ | 1 |
| Llopis, J | 1 |
| Romá, J | 1 |
| Shea, TB | 1 |
| Beermann, ML | 1 |
| Heikkilä, JE | 1 |
| Akerlind, G | 1 |
| Akerman, KE | 1 |
6 other studies available for ha 1004 and Neuroblastoma
| Article | Year |
|---|---|
The role of protein kinase C in inducing Alzheimer's A68 protein expression in the culture of human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Humans; Immunoblotting; Immun | 1994 |
Differential effects of the protein kinase C inhibitors H7 and calphostin C on the cell cycle of neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Cycle; Cell Membrane Permeability; Cell | 1992 |
H7, a protein kinase C inhibitor, increases the glutathione content of neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Enzyme Activation; Glutathione; I | 1992 |
Staurosporine-induced morphological differentiation of human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Axons; Cell Differentiation; Colchicine; C | 1991 |
A specific inhibitor of protein kinase C induces differentiation of neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Cell Differentiati | 1990 |
Protein kinase C activation and down-regulation in relation to phorbol ester-induced differentiation of SH-SY5Y human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Calcium Channels; Cell Compartmentation; Cel | 1989 |