isradipine has been researched along with Neuroblastoma in 6 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbachol-stimulated increase in [Ca2+]i was blocked by atropine and Ni2+ but was totally resistant to the L- and N-channel blockers." | 1.28 | Different mechanisms of Ca2+ entry induced by depolarization and muscarinic receptor stimulation in SH-SY5Y human neuroblastoma cells. ( Baird, JG; Lambert, DG; Nahorski, SR; Whitham, EM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, X | 1 |
| Li, X | 1 |
| Jiang, G | 1 |
| Wang, X | 1 |
| Chang, HC | 1 |
| Hsu, WH | 1 |
| Li, Q | 1 |
| Hirota, K | 1 |
| Lambert, DG | 2 |
| Donnelly-Roberts, DL | 1 |
| Arneric, SP | 1 |
| Sullivan, JP | 1 |
| Ichida, S | 1 |
| Wada, T | 1 |
| Nakazaki, S | 1 |
| Matsuda, N | 1 |
| Kishino, H | 1 |
| Akimoto, T | 1 |
| Whitham, EM | 1 |
| Baird, JG | 1 |
| Nahorski, SR | 1 |
| Eckert, R | 1 |
| Hescheler, J | 1 |
| Krautwurst, D | 1 |
| Schultz, G | 1 |
| Trautwein, W | 1 |
6 other studies available for isradipine and Neuroblastoma
| Article | Year |
|---|---|
Isradipine prevents rotenone-induced intracellular calcium rise that accelerates senescence in human neuroblastoma SH-SY5Y cells.
Topics: Calcium; Cell Line, Tumor; Cellular Senescence; Humans; Intracellular Fluid; Isradipine; Neuroblasto | 2013 |
Measurement of [³H]PN200-110 and [¹²⁵I]ω-conotoxin MVIIA binding.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cell L | 2005 |
Functional modulation of human "ganglionic-like" neuronal nicotinic acetylcholine receptors (nAChRs) by L-type calcium channel antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Specific bindings of [3H](+)PN200-110 and [125I]omega-conotoxin to crude membranes from differentiated NG108-15 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Different mechanisms of Ca2+ entry induced by depolarization and muscarinic receptor stimulation in SH-SY5Y human neuroblastoma cells.
Topics: Atropine; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cell Membrane; Humans; Isradipine | 1990 |
Calcium currents of neuroblastoma x glioma hybrid cells after cultivation with dibutyryl cyclic AMP and nickel.
Topics: Animals; Bucladesine; Calcium Channels; Colforsin; Cycloheximide; Glioma; Hybrid Cells; Isradipine; | 1990 |