2,3-dihydroxybenzoic acid has been researched along with Neuroblastoma in 1 studies
2,3-dihydroxybenzoic acid: RN given refers to parent cpd
dihydroxybenzoic acid : Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives.
2,3-dihydroxybenzoic acid : A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The iron chelator, deferoxamine, has demonstrated cytotoxicity against neuroblastoma cells." | 7.67 | Comparison of activity of deferoxamine with that of oral iron chelators against human neuroblastoma cell lines. ( Blatt, J; Kontoghiorghes, GJ; Taylor, SR, 1989) |
| "The iron chelator, deferoxamine, has demonstrated cytotoxicity against neuroblastoma cells." | 3.67 | Comparison of activity of deferoxamine with that of oral iron chelators against human neuroblastoma cell lines. ( Blatt, J; Kontoghiorghes, GJ; Taylor, SR, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blatt, J | 1 |
| Taylor, SR | 1 |
| Kontoghiorghes, GJ | 1 |
1 other study available for 2,3-dihydroxybenzoic acid and Neuroblastoma
| Article | Year |
|---|---|
Comparison of activity of deferoxamine with that of oral iron chelators against human neuroblastoma cell lines.
Topics: Administration, Oral; Cell Cycle; Cell Survival; Deferiprone; Deferoxamine; Humans; Hydroxybenzoates | 1989 |