(2-benzoylethyl)trimethylammonium profile

(2-Benzoylethyl)trimethylammonium, also known as **BTMA**, is a quaternary ammonium compound. It's not a naturally occurring molecule but a synthetic compound with a specific structure:

* **Trimethylammonium group:** This is a positively charged nitrogen atom attached to three methyl groups.
* **Benzoylethyl group:** This is a chain with a benzoyl group (a benzene ring with a carbonyl group attached) and an ethyl group.

**Importance for Research:**

BTMA has gained attention in research due to its **potential biological activities and applications**. Here's a breakdown:

1. **Antimicrobial properties:** Studies have shown that BTMA exhibits antimicrobial activity against various bacteria and fungi. This property makes it potentially valuable for developing new antibacterial and antifungal agents.

2. **Anti-inflammatory effects:** Some research suggests that BTMA might possess anti-inflammatory properties, which could be relevant for treating inflammatory diseases.

3. **Pharmaceutical development:** BTMA's structure and its potential biological activities make it an attractive candidate for developing novel pharmaceuticals. Researchers are exploring its applications in drug delivery, specifically for targeting specific tissues or organs.

4. **Material science:** BTMA can act as a surfactant, meaning it can reduce surface tension. This property makes it useful in creating new materials and coatings with specific properties, such as improved water repellency or adhesion.

5. **Catalysis:** BTMA can be used as a catalyst in organic reactions, potentially leading to new synthetic pathways and efficient processes.

**Overall:** BTMA remains an area of ongoing research, and its true potential in various fields is still being explored. Its unique properties make it a promising compound for developing new solutions in healthcare, material science, and other areas.

**Important Note:** While there's potential, it's crucial to remember that these applications are still under investigation. More research is needed to fully understand the benefits and risks associated with BTMA before it can be widely implemented.

(2-benzoylethyl)trimethylammonium: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	152676
SCHEMBL ID	10256392
MeSH ID	M0067506

Synonym
NCIOPEN2_008256 ,
(2-benzoylethyl)trimethylammonium
trimethyl-(3-oxo-3-phenylpropyl)azanium
benzenepropanaminium, n,n,n-trimethyl-gamma-oxo-
SCHEMBL10256392
DTXSID00179240
trimethyl-(3-oxo-3-phenyl-propyl)azanium

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	8 (72.73)	18.7374
1990's	2 (18.18)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (9.09)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	13 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
choline [no description available]	2.4	2	cholines	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter; nutrient; plant metabolite; Saccharomyces cerevisiae metabolite
vesamicol vesamicol: RN given refers to parent cpd; structure	6.97	1	piperidines
physostigmine Physostigmine: A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.	2.42	2	carbamate ester; indole alkaloid	antidote to curare poisoning; EC 3.1.1.8 (cholinesterase) inhibitor; miotic
2-aminoisobutyric acid 2-aminoisobutyric acid: RN given refers to unlabeled cpd. 2-aminoisobutyric acid : A rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin. With the exception of a few bacteria, it is non-metabolisable, and therefore used in bioassays.	2.36	2	2,2-dialkylglycine zwitterion; 2,2-dialkylglycine
hemicholinium 3 Hemicholinium 3: A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system. Since choline is one of the components of ACETYLCHOLINE, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.	2.11	1
ouabain Ouabain: A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.. cardiac glycoside : Steroid lactones containing sugar residues that act on the contractile force of the cardiac muscles.. ouabain : A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.	1.96	1	11alpha-hydroxy steroid; 14beta-hydroxy steroid; 5beta-hydroxy steroid; alpha-L-rhamnoside; cardenolide glycoside; steroid hormone	anti-arrhythmia drug; cardiotonic drug; EC 2.3.3.1 [citrate (Si)-synthase] inhibitor; EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; ion transport inhibitor; plant metabolite
acetyl coenzyme a Acetyl Coenzyme A: Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.	2.11	1	acyl-CoA	acyl donor; coenzyme; effector; fundamental metabolite
dinoprostone prostaglandin E2 : Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.	1.97	1	prostaglandins E	human metabolite; mouse metabolite; oxytocic
dinoprost Dinoprost: A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.. prostaglandin F2alpha : A prostaglandins Falpha that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It is a naturally occurring prostaglandin used to induce labor.	1.97	1	monocarboxylic acid; prostaglandins Falpha	human metabolite; mouse metabolite
naphthylvinylpyridine Naphthylvinylpyridine: 4(1-Naphthylvinyl)pyridine hydrochloride. Cholinesterase inhibitor. Synonym: YuB 25.	2.36	2
piperidines Piperidines: A family of hexahydropyridines.	1.97	1

Condition	Relationship Strength	Studies
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	3.21	6
Experimental Neoplasms [description not available]	1.96	1
Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)	1.96	1

(2-benzoylethyl)trimethylammonium

Description

Cross-References

Synonyms (7)

Research

Studies (11)

Market Indicators

Research Demand Index: 11.52

Study Types