carbamazepine has been researched along with Neuroblastoma in 12 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A metastatic neuroblastoma was detected immediately after birth in a boy born to a 26 year old woman with bipolar disorder, who received carbamazepine (400 mg/day) all through her pregnancy." | 7.70 | Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy. ( Araujo, H; Baptista, T; Hernández, L; Rada, P, 1998) |
| "Effects of the antiepileptic drug carbamazepine on nerve action potential and transmitter release in mouse neuroblastoma-glioma hybrid cells (NG108-15) and the frog neuromuscular junction were studied." | 7.70 | Effects of carbamazepine on nerve activity and transmitter release in neuroblastoma-glioma hybrid cells and the frog neuromuscular junction. ( Enomoto, K; Maeno, T; Matsumoto, Y; Moritake, K, 1998) |
| "Lithium, carbamazepine and sodium valproate are mood stabilizers used in the treatment of bipolar disorder, and although their mechanisms of action remain unknown, signal transduction systems and the associated modulation of gene expression may constitute significant actions." | 7.70 | Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells. ( Jope, RS; Pacheco, MA, 1999) |
| " To characterize further the mechanism of action of lamotrigine, we have investigated the effects of this drug together with the anticonvulsant drugs phenytoin and carbamazepine on voltage-sensitive sodium channels present in N4TG1 mouse neuroblastoma clonal cells." | 7.68 | Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells. ( Cooper, BR; Lang, DG; Wang, CM, 1993) |
| "The actions of diphenylhydantoin (DPH) and carbamazepine (CBZ) on sodium channels in mouse neuroblastoma cells (clone N18) were analyzed using the patch voltage clamp procedure in the whole cell configuration." | 7.67 | Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells. ( Catterall, WA; Gonoi, T; Willow, M, 1985) |
| " The dose-response relationships for carbamazepine and diphenylhydantoin inhibition of 22Na+ flux in N18 cells are shifted 1." | 5.27 | Inhibition of voltage-sensitive sodium channels in neuroblastoma cells and synaptosomes by the anticonvulsant drugs diphenylhydantoin and carbamazepine. ( Catterall, WA; Kuenzel, EA; Willow, M, 1984) |
| " We differentiated and treated human SK-N-SH neuroblastoma cells with a mixture (fluoxetine, carbamazepine and venlafaxine) and valproate (used as a positive control to induce autism-associated profiles), followed by transcriptome analysis with RNA-Seq approach." | 3.83 | Psychoactive pharmaceuticals at environmental concentrations induce in vitro gene expression associated with neurological disorders. ( Kaushik, G; Thomas, MA; Xia, Y; Yang, L, 2016) |
| " We performed both comprehensive and gene-specific analyses to examine DNA methylation in human neuroblastoma SK-N-SH cells treated with three mood stabilizers: lithium, valproate and carbamazepine." | 3.79 | Effect of mood stabilizers on DNA methylation in human neuroblastoma cells. ( Asai, T; Bundo, M; Ishigooka, J; Iwamoto, K; Kasai, K; Kato, T; Sugawara, H; Sunaga, F; Tanaka, G; Ueda, J, 2013) |
| " A metastatic neuroblastoma was detected immediately after birth in a boy born to a 26 year old woman with bipolar disorder, who received carbamazepine (400 mg/day) all through her pregnancy." | 3.70 | Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy. ( Araujo, H; Baptista, T; Hernández, L; Rada, P, 1998) |
| "Effects of the antiepileptic drug carbamazepine on nerve action potential and transmitter release in mouse neuroblastoma-glioma hybrid cells (NG108-15) and the frog neuromuscular junction were studied." | 3.70 | Effects of carbamazepine on nerve activity and transmitter release in neuroblastoma-glioma hybrid cells and the frog neuromuscular junction. ( Enomoto, K; Maeno, T; Matsumoto, Y; Moritake, K, 1998) |
| "Lithium, carbamazepine and sodium valproate are mood stabilizers used in the treatment of bipolar disorder, and although their mechanisms of action remain unknown, signal transduction systems and the associated modulation of gene expression may constitute significant actions." | 3.70 | Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells. ( Jope, RS; Pacheco, MA, 1999) |
| "The influence of diazepam, an agonist, and flumazenil (Ro 15-1788), an antagonist of the benzodiazepine receptor, on repetitive firing of action potentials in cultured spinal neurons and on voltage-dependent Na+ currents in cultured N2A neuroblastoma cells was examined." | 3.68 | Action of diazepam on the voltage-dependent Na+ current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil. ( Backus, KH; Pflimlin, P; Trube, G, 1991) |
| "The actions of diphenylhydantoin (DPH) and carbamazepine (CBZ) on sodium channels in mouse neuroblastoma cells (clone N18) were analyzed using the patch voltage clamp procedure in the whole cell configuration." | 3.67 | Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells. ( Catterall, WA; Gonoi, T; Willow, M, 1985) |
| " The dose-response relationships for carbamazepine and diphenylhydantoin inhibition of 22Na+ flux in N18 cells are shifted 1." | 1.27 | Inhibition of voltage-sensitive sodium channels in neuroblastoma cells and synaptosomes by the anticonvulsant drugs diphenylhydantoin and carbamazepine. ( Catterall, WA; Kuenzel, EA; Willow, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kakumoto, M | 1 |
| Shimokawa, K | 1 |
| Ueshima, S | 1 |
| Hira, D | 1 |
| Okano, T | 1 |
| Asai, T | 1 |
| Bundo, M | 1 |
| Sugawara, H | 1 |
| Sunaga, F | 1 |
| Ueda, J | 1 |
| Tanaka, G | 1 |
| Ishigooka, J | 1 |
| Kasai, K | 1 |
| Kato, T | 1 |
| Iwamoto, K | 1 |
| Kaushik, G | 1 |
| Xia, Y | 1 |
| Yang, L | 1 |
| Thomas, MA | 1 |
| Huang, CW | 1 |
| Huang, CC | 1 |
| Lin, MW | 1 |
| Tsai, JJ | 1 |
| Wu, SN | 1 |
| Willow, M | 2 |
| Kuenzel, EA | 1 |
| Catterall, WA | 2 |
| Lang, DG | 1 |
| Wang, CM | 1 |
| Cooper, BR | 1 |
| Baptista, T | 1 |
| Araujo, H | 1 |
| Rada, P | 1 |
| Hernández, L | 1 |
| Matsumoto, Y | 1 |
| Enomoto, K | 1 |
| Moritake, K | 1 |
| Maeno, T | 1 |
| Pacheco, MA | 1 |
| Jope, RS | 1 |
| Lewin, E | 1 |
| Backus, KH | 1 |
| Pflimlin, P | 1 |
| Trube, G | 1 |
| Gonoi, T | 1 |
12 other studies available for carbamazepine and Neuroblastoma
| Article | Year |
|---|---|
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
Topics: Anticonvulsants; Carbamazepine; Cell Line, Tumor; Cell Proliferation; Child; Epilepsy; Female; Human | 2021 |
Effect of mood stabilizers on DNA methylation in human neuroblastoma cells.
Topics: Antimanic Agents; Brain-Derived Neurotrophic Factor; Carbamazepine; Cell Line, Tumor; CpG Islands; D | 2013 |
Psychoactive pharmaceuticals at environmental concentrations induce in vitro gene expression associated with neurological disorders.
Topics: Animals; Autistic Disorder; Carbamazepine; Cell Line, Tumor; Environmental Pollutants; Fluoxetine; G | 2016 |
The synergistic inhibitory actions of oxcarbazepine on voltage-gated sodium and potassium currents in differentiated NG108-15 neuronal cells and model neurons.
Topics: Animals; Anticonvulsants; Carbamazepine; Cell Differentiation; Cell Line, Tumor; Cyclic AMP; Dose-Re | 2008 |
Inhibition of voltage-sensitive sodium channels in neuroblastoma cells and synaptosomes by the anticonvulsant drugs diphenylhydantoin and carbamazepine.
Topics: Animals; Batrachotoxins; Brain; Carbamazepine; Electric Conductivity; Ion Channels; Membrane Potenti | 1984 |
Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Lamotrigine; Mice; Neurob | 1993 |
Congenital neuroblastoma in a boy born to a woman with bipolar disorder treated with carbamazepine during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Gland Neoplasms; Adult; Anticonvulsants; Bipolar Disorder; Carb | 1998 |
Effects of carbamazepine on nerve activity and transmitter release in neuroblastoma-glioma hybrid cells and the frog neuromuscular junction.
Topics: Action Potentials; Animals; Calcium; Carbamazepine; Glioma; Mice; Neuroblastoma; Neuromuscular Block | 1998 |
Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antipsychotic Agents; Bipolar Disorder; Calcium; Calc | 1999 |
Effects of phenytoin on the release of 14C-adenine derivatives.
Topics: Adenine; Animals; Astrocytoma; Brain Neoplasms; Carbamazepine; Cells, Cultured; Cerebral Cortex; Hyp | 1977 |
Action of diazepam on the voltage-dependent Na+ current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil.
Topics: Action Potentials; Animals; Carbamazepine; Cell Line; Cells, Cultured; Diazepam; Embryo, Mammalian; | 1991 |
Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells.
Topics: Animals; Carbamazepine; Cells, Cultured; Electric Stimulation; Ion Channels; Mice; Neuroblastoma; Ph | 1985 |