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sulpiride and Neuroblastoma

sulpiride has been researched along with Neuroblastoma in 8 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Transfection of a human dopamine D3 receptor cDNA in a neuroblastoma-glioma hybrid cell line (NG 108-15) provided clonal cell lines stably expressing up to 600 fmol per mg protein of [125I]iodosulpiride binding sites."3.69Functional coupling of the human dopamine D3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line. ( Dimitriadou, V; Griffon, N; Lévesque, D; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P, 1994)
"[125I] Iodosulpride binding was examined on eight human cell lines derived from lung, breast and digestive tract carcinomas, neuroblastomas and leukemia."3.67Presence of dopamine D-2 receptors in human tumoral cell lines. ( Martres, MP; Riou, JF; Schwartz, JC; Sokoloff, P, 1989)
"Dopamine at 100 mumol L-1 was toxic when added to cultures 24 h after plating."1.29Toxicity of dopamine to mouse neuroblastoma x rat glioma hybrid (NG108) cells in vitro. ( Wang, RG; Zhu, XZ, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's6 (75.00)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoenicka, J1
Quiñones-Lombraña, A1
España-Serrano, L1
Alvira-Botero, X1
Kremer, L1
Pérez-González, R1
Rodríguez-Jiménez, R1
Jiménez-Arriero, MA1
Ponce, G1
Palomo, T1
Wang, RG1
Zhu, XZ1
Seabrook, GR1
Kemp, JA1
Freedman, SB1
Patel, S1
Sinclair, HA1
McAllister, G1
Pilon, C2
Lévesque, D1
Dimitriadou, V1
Griffon, N2
Martres, MP2
Schwartz, JC3
Sokoloff, P3
Farooqui, SM1
Sautel, F1
Lovenberg, TW1
Roth, RH1
Nichols, DE1
Mailman, RB1
Riou, JF1

Other Studies

8 other studies available for sulpiride and Neuroblastoma

ArticleYear
The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine.
    Biological psychiatry, 2010, Jan-01, Volume: 67, Issue:1

    Topics: Animals; Apomorphine; Astrocytes; Cells, Cultured; Central Nervous System; Dopamine Agonists; Embryo

2010
Toxicity of dopamine to mouse neuroblastoma x rat glioma hybrid (NG108) cells in vitro.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:4

    Topics: Animals; Benzazepines; Catalase; Cell Survival; Dopamine; Glioma; Hybrid Cells; Mice; Neuroblastoma;

1995
Functional expression of human D3 dopamine receptors in differentiated neuroblastoma x glioma NG108-15 cells.
    British journal of pharmacology, 1994, Volume: 111, Issue:2

    Topics: Brain Neoplasms; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Dopamine Agents;

1994
Functional coupling of the human dopamine D3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line.
    European journal of pharmacology, 1994, Jul-15, Volume: 268, Issue:2

    Topics: Animals; Cyclic AMP; Ergolines; Genes, fos; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotrip

1994
Induction of adenylate cyclase sensitive dopamine D2-receptors in retinoic acid induced differentiated human neuroblastoma SHSY-5Y cells.
    Life sciences, 1994, Volume: 55, Issue:24

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Base Sequence; Benzamides; Cell Differentiation; Cyclic AMP;

1994
Antipsychotics with inverse agonist activity at the dopamine D3 receptor.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:10

    Topics: Animals; Antipsychotic Agents; Calcium; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; DNA

1996
D1 dopamine receptors of NS20Y neuroblastoma cells are functionally similar to rat striatal D1 receptors.
    Journal of neurochemistry, 1991, Volume: 57, Issue:5

    Topics: Benzazepines; Butaclamol; Carbachol; Cell Line; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine; Do

1991
Presence of dopamine D-2 receptors in human tumoral cell lines.
    Biochemical and biophysical research communications, 1989, Jul-31, Volume: 162, Issue:2

    Topics: Apomorphine; Breast Neoplasms; Cell Membrane; Digestive System Neoplasms; Dopamine; Humans; Iodine R

1989