homovanillic acid has been researched along with Neuroblastoma in 243 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The determination of the two urinary catecholamine metabolites homovanillic acid (HVA) and vanillylmandelic acid (VMA) is of crucial importance for the diagnosis and follow-up of neuroblastoma (NB)." | 9.17 | Interchangeability between 24-hour collection and single spot urines for vanillylmandelic and homovanillic acid levels in the diagnosis of neuroblastoma. ( Barco, S; Cangemi, G; Conte, M; Di Cataldo, A; Garaventa, A; Melioli, G; Reggiardo, G; Viscardi, E, 2013) |
| "Gefitinib potently inhibits neuroblastoma proliferation in vitro, and the gefitinib/irinotecan combination shows greater than additive activity against neuroblastoma xenografts." | 9.16 | A single-arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high-risk neuroblastoma. ( Billups, CA; Davidoff, AM; Furman, WL; Hawkins, D; Houghton, PJ; Kovach, S; McCarville, MB; McGregor, LM; McPherson, V; Onciu, M; Santana, VM; Stewart, CF; Wu, J, 2012) |
| "Vanillylmandelic acid (VMA) and homovanillic acid (HVA) are clinical biomarkers for diagnosis of neuroblastoma (NB), which commonly occurs in the childhood." | 7.91 | Analytical validation and clinical application of urinary vanillylmandelic acid and homovanillic acid by LC-MS/MS for diagnosis of neuroblastoma. ( Cheng, L; Guan, Q; Li, H; Lu, J; Luo, X; Shen, Y, 2019) |
| "Vanillylmandelic acid (VMA) and homovanillic acid (HVA) are typically measured in urine for the diagnosis and monitoring of neuroblastoma, a tumor in children <5 y." | 7.79 | Analysis of vanillylmandelic acid and homovanillic acid by UPLC-MS/MS in serum for diagnostic testing for neuroblastoma. ( Benjamin, D; Dugaw, K; Jack, RM; Sadilkova, K, 2013) |
| "The levels of urinary catecholamine metabolites, such as homovanillic acid (HVA) and vanillylmandelic acid, are routinely used as a clinical tool in the diagnosis and follow-up of neuroblastoma (NB) patients." | 7.78 | Identification and structural characterization by LC-ESI-IONTRAP and LC-ESI-TOF of some metabolic conjugation products of homovanillic acid in urine of neuroblastoma patients. ( Barbagallo, L; Barco, S; Benatti, U; Bugnone, D; Cangemi, G; Damonte, G; Maffia, A; Melioli, G; Profumo, A; Scapolla, C, 2012) |
| "Employing 421 urine samples taken randomly from normal infants and 294 samples from infants with neuroblastoma, we investigated the application of values of vanillylmandelic acid (VMA), homovanillic acid (HVA) and square root of VMA2 + HVA2 to discriminate between patients and normal infants." | 7.68 | Urinary vanillylmandelic acid and homovanillic acid levels in randomly-sampled urine for the mass screening of neuroblastoma. ( Hanai, J; Kawai, T; Miyake, H; Nishi, M; Takasugi, N; Takeda, T, 1990) |
| "Fluctuations in the amount of vanillylmandelic acid (VMA) and homovanillic acid (HVA) were studied in random urine samples from 13 infants with neuroblastoma." | 7.68 | Fluctuation in the concentrations of vanillylmandelic acid and homovanillic acid in mass screening for neuroblastoma. ( Hanai, J; Kawai, T; Miyake, H; Nishi, M; Takasugi, N; Takeda, T; Yamashiro, K, 1990) |
| "Neuropeptide Y (NPY) was studied as a marker for neuroblastoma in 12 children." | 7.68 | Serial measurements of neuropeptide Y in plasma for monitoring neuroblastoma in children. ( Feth, F; Hunneman, DH; Kremens, B; Lang, RE; Rascher, W; Wagner, S, 1993) |
| "In 211 patients with neuroblastoma, serum vanillylmandelic acid (VMA) and homovanillic acid (HVA) levels were determined and correlated to stage, histological differentiation, ferritin, neuron-specific enolase, lactate dehydrogenase (LDH) and outcome." | 7.68 | Serum vanillylmandelic acid/homovanillic acid contributes to prognosis estimation in patients with localised but not with metastatic neuroblastoma. ( Berthold, F; Harms, D; Hunneman, DH; Käser, H; Zieschang, J, 1992) |
| "The urinary concentrations of o-hydroxymandelic acid, m-hydroxymandelic acid, p-hydroxymandelic acid, homovanillic acid and vanillylmandelic acid were determined in 57 healthy children and 9 patients with neuroblastoma." | 7.67 | Excretion of octopamine metabolites in neuroblastoma. ( Couch, MW; Greer, DM; Williams, CM, 1986) |
| "We report a method for determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid by high-performance liquid chromatography (HPLC), with coulometric electrochemical detection, for mass screening of neuroblastoma." | 7.67 | Determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid in dried urine on filter-paper discs by high-performance liquid chromatography with coulometric electrochemical detection for neuroblastoma screening. ( Haraguchi, K; Haruki, E; Kinoshita, Y; Mori, Y; Takahashi, T; Takayanagi, T; Yamada, S, 1988) |
| "The amounts of vanillylmandelic acid (VMA), homovanillic acid (HVA), and catecholamines (adrenaline, noradrenaline, and dopamine) in 24-hr urine specimens of 10 infants with neuroblastoma detected through mass screening in Sapporo City (patient group) were compared with those of 24 healthy infants (control group)." | 7.67 | Vanillylmandelic acid, homovanillic acid, and catecholamines in urine of infants with neuroblastoma 6- to 11-month-old. ( Hanai, J; Miyake, H; Nishi, M; Sato, Y; Takasugi, N; Takeda, T, 1986) |
| "In order to develop a mass screening method for the early detection of neuroblastoma, we measured urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) by a high performance liquid chromatography (HPLC) equipped with an electrochemical detector." | 7.67 | Determination of urinary vanillylmandelic acid and homovanillic acid by high performance liquid chromatography for mass screening of neuroblastoma. ( Hanai, J; Sato, Y; Takasugi, N; Takeda, T, 1986) |
| "Urinary homovanillic acid (HVA) and vanillylmandelic acid (VMA) levels were determined in random samples and in 24-hour collections from 13 patients with neuroblastoma and 22 patients without neuroblastoma." | 7.67 | Value of random urinary homovanillic acid and vanillylmandelic acid levels in the diagnosis and management of patients with neuroblastoma: comparison with 24-hour urine collections. ( Bowers, LD; Krivit, W; Morris, CL; Ramnaraine, ML; Tuchman, M, 1985) |
| "We report quantitative data on beta-glucuronidase- and sulfatase-hydrolyzable conjugates of homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid in the urine of 20 apparently normal and healthy control persons and of three patients with neuroblastoma." | 7.66 | Urinary excretion of conjugated homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid by persons on their usual diet and patients with neuroblastoma. ( Groen, A; Muskiet, FA, 1979) |
| "Neuroblastoma is the most common extracranial solid tumor in children." | 5.33 | The secretion of ibuprofen metabolites interferes with the capillary chromatography of urinary homovanillic acid and 4-hydroxy-3-methoxymandelic acid in neuroblastoma diagnosis. ( Buoncompagni, A; Caruso, U; De Bernardi, B; Deiana, F; Levreri, I; Marchese, N; Melioli, G, 2005) |
| "In all, neuroblastoma has been detected in 17 of 88,887 infants so examined since April 1981." | 5.27 | Simple liquid-chromatographic measurement of vanillylmandelic acid and homovanillic acid in urine on filter paper for mass screening of neuroblastoma in infants. ( Hanai, J; Kawai, T; Nishi, M; Sato, Y; Takasugi, N; Takeda, T, 1987) |
| "The determination of the two urinary catecholamine metabolites homovanillic acid (HVA) and vanillylmandelic acid (VMA) is of crucial importance for the diagnosis and follow-up of neuroblastoma (NB)." | 5.17 | Interchangeability between 24-hour collection and single spot urines for vanillylmandelic and homovanillic acid levels in the diagnosis of neuroblastoma. ( Barco, S; Cangemi, G; Conte, M; Di Cataldo, A; Garaventa, A; Melioli, G; Reggiardo, G; Viscardi, E, 2013) |
| "Gefitinib potently inhibits neuroblastoma proliferation in vitro, and the gefitinib/irinotecan combination shows greater than additive activity against neuroblastoma xenografts." | 5.16 | A single-arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high-risk neuroblastoma. ( Billups, CA; Davidoff, AM; Furman, WL; Hawkins, D; Houghton, PJ; Kovach, S; McCarville, MB; McGregor, LM; McPherson, V; Onciu, M; Santana, VM; Stewart, CF; Wu, J, 2012) |
| "Vanillylmandelic acid (VMA) and homovanillic acid (HVA) are diagnostic markers of neuroblastoma." | 4.31 | Voltammetric Detection of Vanillylmandelic Acid and Homovanillic Acid Using Urea-Derivative-Modified Graphite Electrode. ( Králík, F; Shishkanova, TV; Synytsya, A, 2023) |
| "Vanillylmandelic acid (VMA) and homovanillic acid (HVA) are clinical biomarkers for diagnosis of neuroblastoma (NB), which commonly occurs in the childhood." | 3.91 | Analytical validation and clinical application of urinary vanillylmandelic acid and homovanillic acid by LC-MS/MS for diagnosis of neuroblastoma. ( Cheng, L; Guan, Q; Li, H; Lu, J; Luo, X; Shen, Y, 2019) |
| "Urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) are biomarkers for the diagnosis and follow-up of neuroblastoma, whereas urinary 5-hydroxyindoleacetic acid (5-HIAA) is used to assess a carcinoid tumor." | 3.88 | Quantification of vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid in urine using a dilute-and-shoot and ultra-high pressure liquid chromatography tandem mass spectrometry method. ( Centeno, C; Eugster, PJ; Grouzmann, E, 2018) |
| "Measurement of the urine catecholamine metabolites homovanillic acid (HVA) and vanillylmandelic acid (VMA) are the standard method for detecting disease recurrence in neuroblastoma." | 3.88 | Olive ingestion causing a false suspicion of relapsed neuroblastoma: A case of "oliveblastoma?" ( Flynn, N; Hogg, SL; LeFebvre, A; Messahel, B, 2018) |
| "Vanillylmandelic acid (VMA) and homovanillic acid (HVA) are typically measured in urine for the diagnosis and monitoring of neuroblastoma, a tumor in children <5 y." | 3.79 | Analysis of vanillylmandelic acid and homovanillic acid by UPLC-MS/MS in serum for diagnostic testing for neuroblastoma. ( Benjamin, D; Dugaw, K; Jack, RM; Sadilkova, K, 2013) |
| "The urinary excretion of vanillylmandelic acid (VMA), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) can be increased in the presence of neuroblastic and carcinoid tumors." | 3.74 | HPLC-mass spectrometry method for quantitative detection of neuroendocrine tumor markers: vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid. ( Cardelli, P; Lionetto, L; Lostia, AM; Simmaco, M; Stigliano, A, 2008) |
| " This work reports the development of a silicon-based integrated separation microsystem for gas chromatography aimed to biomedical applications, with particular emphasis to monitor the homovanillic acid (HVA) and vanillylmandelic acid (VMA) ratios in mass population screening for neuroblastoma diagnosis and prognosis." | 3.73 | Development of a gas chromatography silicon-based microsystem in clinical diagnostics. ( Adami, A; Benvenuto, A; Guarnieri, V; Lorenzelli, L; Margesin, B; Mulloni, V; Vincenzi, D, 2005) |
| "combined determination of normetanephrine with vanillylmandelic acid (0-1 year) or homovanillic acid (1-5 years and 5-10 years) further enhanced the diagnostic power up to 100% sensitivity and specificity of the testing depending on the age group." | 3.72 | Comparative values of catecholamines and metabolites for the diagnosis of neuroblastoma. ( Corcuff, JB; Monsaingeon, M; Perel, Y; Simonnet, G, 2003) |
| "The value of the tumour markers vanillylmandelic acid (VMA) and homovanillic acid (HVA) in urine (u) and serum (s), neurone-specific enolase (NSE), and lactate dehydrogenase (LDH) in the early prediction of relapse/progression in neuroblastoma is not known." | 3.72 | Tumour markers are poor predictors for relapse or progression in neuroblastoma. ( Berthold, F; Hero, B; Hunneman, DH; Simon, T, 2003) |
| " N-Methyl(R)salsolinol induced DNA damage to human neuroblastoma SH-SY5Y cells, which could be prevented by anti-oxidants and cycloheximide." | 3.70 | Oxidation of N-methyl(R)salsolinol: involvement to neurotoxicity and neuroprotection by endogenous catechol isoquinolines. ( Dostert, P; Kasamatsu, T; Maruyama, W; Naoi, M, 1998) |
| "In Japan, a nationwide mass screening (MS) program for preclinical detection of neuroblastoma in infants was done by measuring urinary vanillylmandelic acid and homovanillic acid at the age of 6 months." | 3.69 | One hundred neuroblastomas detected through a mass screening system in Japan. ( Hachitanda, Y; Hata, J; Ishimoto, K; Shimada, H, 1994) |
| "Nineteen children suffering from neuroblastoma were analysed retrospectively by 123I-mIBG-scintigraphy, bone scintigraphy and measurement of homovanillic acid, vanillic acid, neuronspecific enclose, lactate dehydrogenase, and ferritine." | 3.69 | [Follow up control of stage IV neuroblastoma: 123I-MIBG scintigraphy, bone scintigraphy and catecholamine metabolites]. ( Jürgens, H; Kohnert, K; Lerch, H; Schober, O; Thelen, M, 1996) |
| "Infants were screened for preclinical detection of neuroblastoma by determination of catecholamine metabolites, vanillylmandelic acid (VMA), and homovanillic acid (HVA)." | 3.69 | Screening for neuroblastoma in North America. Preliminary results of a pathology review from the Quebec Project. ( Bernstein, M; Brisson, L; Brossard, J; Byrne, TD; Hachitanda, Y; Leclerc, JM; Lemieux, B; Takeuchi, LA; Tuchman, M; Woods, WG, 1995) |
| "Employing 421 urine samples taken randomly from normal infants and 294 samples from infants with neuroblastoma, we investigated the application of values of vanillylmandelic acid (VMA), homovanillic acid (HVA) and square root of VMA2 + HVA2 to discriminate between patients and normal infants." | 3.68 | Urinary vanillylmandelic acid and homovanillic acid levels in randomly-sampled urine for the mass screening of neuroblastoma. ( Hanai, J; Kawai, T; Miyake, H; Nishi, M; Takasugi, N; Takeda, T, 1990) |
| "The mass screening of neuroblastoma has been undertaken in Japan by measuring urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) in all infants at the age of 6 months." | 3.68 | Different genomic and metabolic patterns between mass screening-positive and mass screening-negative later-presenting neuroblastomas. ( Akiyama, H; Ikeda, K; Kawakami, K; Nagahara, N; Nakagawara, A; Ohgami, H; Sera, Y; Suita, S; Uchino, J; Zaizen, Y, 1991) |
| "A 2-month-old infant had a retroperitoneal tumor and increased levels of vanillylmandelic acid and homovanillic acid in the urine, indicating an abdominal neuroblastoma." | 3.68 | Presumed iris metastasis from abdominal neuroblastoma. ( Hayasaka, S; Kishi, K; Sekimoto, M; Setogawa, T, 1991) |
| "In 211 patients with neuroblastoma, serum vanillylmandelic acid (VMA) and homovanillic acid (HVA) levels were determined and correlated to stage, histological differentiation, ferritin, neuron-specific enolase, lactate dehydrogenase (LDH) and outcome." | 3.68 | Serum vanillylmandelic acid/homovanillic acid contributes to prognosis estimation in patients with localised but not with metastatic neuroblastoma. ( Berthold, F; Harms, D; Hunneman, DH; Käser, H; Zieschang, J, 1992) |
| "In Japan, aiming at early and preclinical detection of neuroblastoma in infancy a mass screening program for the tumor has been implemented nationwide using urinary tests for catecholamine metabolites, vanillylmandelic acid (VMA) and homovanillic acid (HVA) (Sawada 1990; Sawada et al." | 3.68 | Mass screening for neuroblastoma in Miyagi Prefecture. ( Fujie, H; Itano, M; Konno, T; Minegishi, M; Minegishi, N; Morita, S; Ohashi, Y; Sato, T; Tsuchiya, S; Yamaguchi, Y, 1992) |
| "Neuropeptide Y (NPY) was studied as a marker for neuroblastoma in 12 children." | 3.68 | Serial measurements of neuropeptide Y in plasma for monitoring neuroblastoma in children. ( Feth, F; Hunneman, DH; Kremens, B; Lang, RE; Rascher, W; Wagner, S, 1993) |
| "Fluctuations in the amount of vanillylmandelic acid (VMA) and homovanillic acid (HVA) were studied in random urine samples from 13 infants with neuroblastoma." | 3.68 | Fluctuation in the concentrations of vanillylmandelic acid and homovanillic acid in mass screening for neuroblastoma. ( Hanai, J; Kawai, T; Miyake, H; Nishi, M; Takasugi, N; Takeda, T; Yamashiro, K, 1990) |
| "The diurnal variation of urinary homovanillic acid (HVA) and vanillylmandelic acid (VMA) was studied in neuroblastoma patients and in a control group." | 3.67 | Assessment of the diurnal variations in urinary homovanillic and vanillylmandelic acid excretion for the diagnosis and follow-up of patients with neuroblastoma. ( Krivit, W; Maynard, RC; Ramnaraine, ML; Robison, LL; Tuchman, M, 1985) |
| "Twenty-two reported cases of neuroblastoma missed by the mass screening programs were reviewed (six cases in Sapporo City where a quantitative measurement for both vanillylmandelic acid (VMA) and homovanillic acid (HVA) is used and 16 cases in the districts of qualitative judgment only for VMA), and some potential factors for missing a patient were discussed." | 3.67 | Cases of neuroblastoma missed by the mass screening programs. ( Hanai, J; Kawai, T; Miyake, H; Nishi, M; Sato, Y; Takasugi, N; Takeda, T, 1989) |
| "Urinary excretion of cystathionine and dopa metabolites was analyzed in 61 patients with active neuroblastoma before, and at regular intervals during treatment." | 3.67 | Cystathioninuria in patients with neuroblastoma. ( Abeling, NG; Rajnherc, JR; van der Zee, JM; van Gennip, AH; Voûte, PA, 1984) |
| "The urinary concentrations of o-hydroxymandelic acid, m-hydroxymandelic acid, p-hydroxymandelic acid, homovanillic acid and vanillylmandelic acid were determined in 57 healthy children and 9 patients with neuroblastoma." | 3.67 | Excretion of octopamine metabolites in neuroblastoma. ( Couch, MW; Greer, DM; Williams, CM, 1986) |
| "We report a method for determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid by high-performance liquid chromatography (HPLC), with coulometric electrochemical detection, for mass screening of neuroblastoma." | 3.67 | Determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid in dried urine on filter-paper discs by high-performance liquid chromatography with coulometric electrochemical detection for neuroblastoma screening. ( Haraguchi, K; Haruki, E; Kinoshita, Y; Mori, Y; Takahashi, T; Takayanagi, T; Yamada, S, 1988) |
| "A method for determining serum catecholamine metabolites such as vanillylmandelic acid (VMA), 3-methoxy-4-hydroxyphenyl glycol (MHPG) and homovanillic acid (HVA) in neuroblastoma by using high performance liquid chromatography and electrochemical detector is described." | 3.67 | Determination of serum catecholamine metabolites in neuroblastoma by high performance liquid chromatography with electrochemical detection. ( Jin, BX; Shi, YQ; Tang, QM; Xu, XR, 1986) |
| "Seasonal variations in urinary levels of vanillylmandelic acid (VMA) and homovanillic acid (HVA) have been investigated over a two-year period, using 31,466 filter-paper specimens of urine from infants of 6 months of age who underwent Sapporo City's screening for neuroblastoma." | 3.67 | Seasonal variations in vanillylmandelic acid and homovanillic acid in infants' urine. ( Hanai, J; Miyake, H; Nishi, M; Sato, Y; Takasugi, N; Takeda, T, 1987) |
| "The amounts of vanillylmandelic acid (VMA), homovanillic acid (HVA), and catecholamines (adrenaline, noradrenaline, and dopamine) in 24-hr urine specimens of 10 infants with neuroblastoma detected through mass screening in Sapporo City (patient group) were compared with those of 24 healthy infants (control group)." | 3.67 | Vanillylmandelic acid, homovanillic acid, and catecholamines in urine of infants with neuroblastoma 6- to 11-month-old. ( Hanai, J; Miyake, H; Nishi, M; Sato, Y; Takasugi, N; Takeda, T, 1986) |
| "During the last 3 years, random urine samples from 408 patients were tested for elevated homovanillic acid (HVA) and vanillylmandelic acid (VMA) levels to rule out the diagnosis of neuroblastoma." | 3.67 | Three years of experience with random urinary homovanillic and vanillylmandelic acid levels in the diagnosis of neuroblastoma. ( Krivit, W; Ramnaraine, ML; Tuchman, M; Woods, WG, 1987) |
| "In order to develop a mass screening method for the early detection of neuroblastoma, we measured urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) by a high performance liquid chromatography (HPLC) equipped with an electrochemical detector." | 3.67 | Determination of urinary vanillylmandelic acid and homovanillic acid by high performance liquid chromatography for mass screening of neuroblastoma. ( Hanai, J; Sato, Y; Takasugi, N; Takeda, T, 1986) |
| "Urinary homovanillic acid (HVA) and vanillylmandelic acid (VMA) levels were determined in random samples and in 24-hour collections from 13 patients with neuroblastoma and 22 patients without neuroblastoma." | 3.67 | Value of random urinary homovanillic acid and vanillylmandelic acid levels in the diagnosis and management of patients with neuroblastoma: comparison with 24-hour urine collections. ( Bowers, LD; Krivit, W; Morris, CL; Ramnaraine, ML; Tuchman, M, 1985) |
| "The catecholic amino acids, dopa and 5-S-cysteinyldopa, and the dopamine metabolite, homovanillic acid, were determined in 8 neuroblastomas." | 3.66 | Melanogenesis in cultured human neuroblastomas. ( Aubert, C; Hansson, C; Janiaud, P; Rorsman, H; Rosengren, E; Rouge, F, 1980) |
| "We report quantitative data on beta-glucuronidase- and sulfatase-hydrolyzable conjugates of homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid in the urine of 20 apparently normal and healthy control persons and of three patients with neuroblastoma." | 3.66 | Urinary excretion of conjugated homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid by persons on their usual diet and patients with neuroblastoma. ( Groen, A; Muskiet, FA, 1979) |
| "Urinary catecholamine catabolites, homovanillic acid, vanillylmandelic acid, total metanephrines, and total catecholamines were assayed in 12 patients with newly diagnosed retinoblastoma prior to surgery and treatment." | 3.66 | Normal urinary excretion of catecholamine catabolites in children with retinoblastoma. ( Dyment, PG; Levin, HS; Orlowski, JP; Price, RL, 1978) |
| " Consequently, this reaction has long been used to measure tyrosine in tyrosinosis and tyrosinemia, homovanillic acid in neuroblastoma, and 5-hydroxy-3-indoleacetic acid in the carcinoid tumor." | 3.66 | The chemical basis and specificity of the nitrosonaphthol reaction. ( Knight, JA; Robertson, G; Wu, JT, 1983) |
| "The interference of various foodstuffs on methods to determine epinephrine (E), norepinephrine (NE), vanillylmandelic acid (VMA), metanephrines (MN), homovanillic acid (HVA), and 6-hydroxyindole acetic acid (5-HIA) in the 24 h urine for diagnosis of pheochromocytoma and carcinoid syndrome, respectively, was investigated." | 3.66 | [The influence of different diets and smoking on the clinical chemical diagnosis of pheochromocytoma, neuroblastoma, and carcinoid syndrome (author's transl)]. ( Eberhagen, D; Heinemann, G; Rahlfs, V; Schievelbein, H, 1981) |
| "By means of thin-layer chromatographic methods, iso-homovanillic acid (iso-HVA), iso-vanillactic acid (iso-VLA) and iso-vanilmandelic acid (iso-VMA) were determined in the urine of 10 children with neuroblastoma." | 3.65 | Para-O-methylation of the catecholamines in neuroblastoma. ( Ebinger, G; Verheyden, R, 1975) |
| "Neuroblastoma is the most common extracranial solid tumour occurring in childhood and has a diverse clinical presentation and course depending on the tumour biology." | 2.53 | Neuroblastoma. ( Diller, L; Mackall, CL; Maris, JM; Matthay, KK; Nakagawara, A; Schleiermacher, G; Weiss, WA, 2016) |
| "No recurrence was observed after disappearance of tumors, and persistent tumors showed no malignant transformation or metastasis." | 1.40 | Long-term follow-up results of the observation program for neuroblastoma detected at 6-month mass screening. ( Aihara, T; Arakawa, A; Hanada, R; Kikuchi, A; Kishimoto, H; Koh, K; Oguma, E, 2014) |
| "Neuroblastoma is the most common extracranial solid tumour in childhood (8% of all childhood cancers), the most frequently diagnosed in infancy, and has one of the highest death rates, while chromaffin tumours rarely present in childhood." | 1.37 | Age-related medical decision limits for urinary free (unconjugated) metadrenalines, catecholamines and metabolites in random urine specimens from children. ( Carachi, R; Davidson, DF; Hammond, PJ; Murphy, D, 2011) |
| "Four had neuroblastoma, one had Ewing sarcoma, and the other had juvenile xanthogranuloma." | 1.33 | Pediatric horner syndrome: etiologies and roles of imaging and urine studies to detect neuroblastoma and other responsible mass lesions. ( Hogarty, MD; Liu, GT; Mahoney, NR; Maris, JM; Menacker, SJ; Wilson, MC, 2006) |
| "Ganglioneuroma is a benign neurogenic tumor." | 1.33 | Ganglioneuroma : primary tumor or maturation of a suspected neuroblastoma? ( Ertel, W; Heyde, CE; Perez-Canto, A; Przkora, R, 2006) |
| "Neuroblastoma is the most common extracranial solid tumor in children." | 1.33 | The secretion of ibuprofen metabolites interferes with the capillary chromatography of urinary homovanillic acid and 4-hydroxy-3-methoxymandelic acid in neuroblastoma diagnosis. ( Buoncompagni, A; Caruso, U; De Bernardi, B; Deiana, F; Levreri, I; Marchese, N; Melioli, G, 2005) |
| "Costello syndrome is a rare congenital anomaly syndrome with a predisposition to specific tumors, including neuroblastoma, rhabdomyosarcoma, and transitional cell carcinoma of the bladder." | 1.32 | Elevated catecholamine metabolites in patients with Costello syndrome. ( Gripp, KW; Kawame, H; Nicholson, L; Viskochil, DH, 2004) |
| "Neuroblastoma is a solid tumor occurring usually in children less than 5 years old." | 1.31 | Simultaneous HPLC of twelve monoamines and metabolites shows neuroblastoma cell line releases HVA and HIAA. ( Chen, HR; Cheng, AT; Hsu, YP; Liu, YL, 2000) |
| "Neuroblastoma was detected in 2 children for an incidence rate of 1 in 7023." | 1.30 | Neuroblastoma screening in the United States: results of the Texas Outreach Program for neuroblastoma screening. ( Ater, JL; Bleyer, WA; Foxhall, LE; Gardner, KL; Therrell, BL, 1998) |
| "Eight neuroblastomas were discovered by-screening (one stage I, three stage II, one stage III, three stage IVs)." | 1.30 | Screening for neuroblastoma in France: methodological aspects and preliminary observations. ( Boschetti, R; Brunat-Mentigny, M; Chauvin, F; Chauvot, P; Combaret, V; David, L; Esteve, J; Favrot, MC; Frappaz, D; Greffe, J; Lasset, C; Mathieu, P; Philip, T; Thiesse, P, 1997) |
| "Six neuroblastomas were found clinically before the age of 4 m." | 1.29 | A 5-year (1990-1994) neuroblastoma screening feasibility study in France. Methodology and preliminary observations. ( Brunat-Mentigny, M; Chauvin, F; Combaret, V; David, L; Esteve, J; Favrot, M; Fouillat, V; Frappaz, D; Greffe, J; Lasset, C; Mathieu, P; Philip, T; Renaud, P; Vercherat, M, 1996) |
| "Infants with neuroblastoma are known to have a better prognosis than older children." | 1.29 | Neuroblastoma in infants aged less than 6 months: is more aggressive treatment necessary? A report from the Pediatric Oncology Study Group of the Kyushu area. ( Kurosaki, N; Miyazaki, S; Mizote, H; Ogami, H; Sera, Y; Suita, S; Takamatsu, H; Tasaka, H; Ueda, K; Zaizen, Y, 1995) |
| "Neuroblastoma is perhaps the most heterogeneous childhood cancer in terms of clinical behavior." | 1.29 | DNA ploidy in neuroblastoma. ( Dahbiová, R; Eckschlager, T; Hrusák, O; Jasinská, J; Kodet, R; Pilát, D; Stanková, J, 1996) |
| "A neuroblastoma was identified in 16 cases." | 1.29 | [5 years neuroblastoma screening in Austria: rate of participation, results and a comparison with other screening areas]. ( Amann, G; Ambros, IM; Ambros, PF; Fauler, G; Gadner, H; Gleispach, H; Höfler, G; Kerbl, R; Kytir, J; Lackner, H; Ladenstein, R; Mutz, I; Rumpler, S; Schnellauf, C; Sitzwohl, C; Spuller, E; Urban, CE, 1996) |
| "Neuroblastomas are malignant tumors derived embryonically from the neural crest." | 1.29 | Urinary excretion of methylated catecholamine metabolites in a child with neuroblastoma maturing into ganglioneuroma. ( Bekri, S; Candito, M; Chambon, P; Deville, A; Soler, C; Thyss, A, 1996) |
| "Screening for neuroblastoma is possible in the health care system of the United Kingdom." | 1.28 | Screening for neuroblastoma in the north of England. ( Bell, S; Cole, M; Craft, AW; Dale, G; McGill, AC; Parker, L; Seviour, JA; Smith, J, 1992) |
| "Neuroblastoma is the most common solid tumour of childhood with an incidence of about 1:10,000 births." | 1.28 | Biochemical screening for neuroblastoma in infants: a feasibility study. ( Craft, AW; Dale, G; McGill, A; Seviour, J; Spence, EM, 1989) |
| "Neuroblastoma is the most common fatal solid tumour of childhood." | 1.27 | Feasibility of chemical screening of urine for neuroblastoma case finding in infancy in Quebec. ( Auray-Blais, C; Bernstein, M; Clow, CL; Dougherty, GE; Giguère, R; Gregory, D; Laberge, C; Lemieux, B; Scriver, CR; Weisdorf, T, 1987) |
| "Neuroblastoma is a disease in which easily measured tumor markers are excreted." | 1.27 | Neuroblastoma: the case for screening infants in North America. ( Tuchman, M; Woods, WG, 1987) |
| "In all, neuroblastoma has been detected in 17 of 88,887 infants so examined since April 1981." | 1.27 | Simple liquid-chromatographic measurement of vanillylmandelic acid and homovanillic acid in urine on filter paper for mass screening of neuroblastoma in infants. ( Hanai, J; Kawai, T; Nishi, M; Sato, Y; Takasugi, N; Takeda, T, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 102 (41.98) | 18.7374 |
| 1990's | 86 (35.39) | 18.2507 |
| 2000's | 30 (12.35) | 29.6817 |
| 2010's | 21 (8.64) | 24.3611 |
| 2020's | 4 (1.65) | 2.80 |
| Authors | Studies |
|---|---|
| Beals, M | 1 |
| Ramoo, B | 1 |
| Clinton Frazee, C | 1 |
| Garg, U | 2 |
| Matser, YAH | 1 |
| Verly, IRN | 1 |
| van der Ham, M | 1 |
| de Sain-van der Velden, MGM | 1 |
| Verhoeven-Duif, NM | 1 |
| Ash, S | 1 |
| Cangemi, G | 4 |
| Barco, S | 4 |
| Popovic, MB | 1 |
| van Kuilenburg, ABP | 1 |
| Tytgat, GAM | 1 |
| Shishkanova, TV | 1 |
| Králík, F | 1 |
| Synytsya, A | 1 |
| Hwang, N | 1 |
| Chong, E | 1 |
| Oh, H | 1 |
| Cho, HW | 1 |
| Lee, JW | 1 |
| Sung, KW | 1 |
| Lee, SY | 1 |
| Amano, H | 1 |
| Uchida, H | 1 |
| Tanaka, Y | 3 |
| Tainaka, T | 1 |
| Mori, M | 1 |
| Oguma, E | 3 |
| Kishimoto, H | 2 |
| Kawashima, H | 1 |
| Arakawa, Y | 1 |
| Hanada, R | 5 |
| Koh, K | 2 |
| Grouzmann, E | 1 |
| Centeno, C | 1 |
| Eugster, PJ | 1 |
| Flynn, N | 1 |
| LeFebvre, A | 1 |
| Messahel, B | 1 |
| Hogg, SL | 1 |
| Shen, Y | 1 |
| Li, H | 1 |
| Lu, J | 1 |
| Luo, X | 1 |
| Guan, Q | 1 |
| Cheng, L | 1 |
| Reggiardo, G | 2 |
| Viscardi, E | 3 |
| Di Cataldo, A | 2 |
| Garaventa, A | 4 |
| Melioli, G | 3 |
| Conte, M | 3 |
| Sadilkova, K | 1 |
| Dugaw, K | 1 |
| Benjamin, D | 1 |
| Jack, RM | 1 |
| Tran, MT | 1 |
| Baglin, J | 1 |
| Tran, TT | 1 |
| Hoang, KT | 1 |
| Phung, LT | 1 |
| Read, A | 1 |
| Greaves, RF | 1 |
| Gennai, I | 1 |
| Galleni, B | 1 |
| Barbagallo, L | 2 |
| Maffia, A | 2 |
| De Leonardis, F | 1 |
| Cecinati, V | 1 |
| Sorrentino, S | 1 |
| Arakawa, A | 1 |
| Aihara, T | 3 |
| Kikuchi, A | 3 |
| Yagi, M | 1 |
| Lee, T | 1 |
| Kusunoki, N | 1 |
| Nagasaka, M | 1 |
| Koda, T | 1 |
| Matsuo, K | 1 |
| Yokota, T | 1 |
| Miwa, A | 1 |
| Shibata, A | 1 |
| Morioka, I | 1 |
| Kodama, H | 1 |
| Takeshima, Y | 1 |
| Iijima, K | 1 |
| Matsuo, M | 1 |
| Tasaki, R | 1 |
| Iwanaga, M | 1 |
| Takayanagi, T | 2 |
| Lam, L | 1 |
| Woollard, GA | 1 |
| Teague, L | 1 |
| Davidson, JS | 1 |
| Selvaratnam, R | 1 |
| Karger, AB | 1 |
| Matthay, KK | 1 |
| Maris, JM | 2 |
| Schleiermacher, G | 1 |
| Nakagawara, A | 5 |
| Mackall, CL | 1 |
| Diller, L | 1 |
| Weiss, WA | 1 |
| Khamlichi, RE | 1 |
| Bouchta, D | 1 |
| Anouar, EH | 1 |
| Atia, MB | 1 |
| Attar, A | 1 |
| Choukairi, M | 1 |
| Tazi, S | 1 |
| Ihssane, R | 1 |
| Faiza, C | 1 |
| Khalid, D | 1 |
| Khalid, RT | 1 |
| Lionetto, L | 1 |
| Lostia, AM | 1 |
| Stigliano, A | 1 |
| Cardelli, P | 1 |
| Simmaco, M | 1 |
| Dau, D | 1 |
| Parodi, S | 1 |
| De Bernardi, B | 3 |
| Giuliano, M | 1 |
| Pession, A | 1 |
| Luksch, R | 1 |
| Castellano, A | 1 |
| Bertuna, G | 1 |
| Haupt, R | 1 |
| Manickum, T | 1 |
| Tanaka, M | 1 |
| Kigasawa, H | 2 |
| Kato, K | 3 |
| Ijiri, R | 2 |
| Nishihira, H | 2 |
| Aida, N | 2 |
| Ohama, Y | 1 |
| Allenbrand, R | 1 |
| Smith, SJ | 1 |
| Diehl, NN | 1 |
| Smith, BD | 1 |
| Mohney, BG | 1 |
| Davidson, DF | 1 |
| Hammond, PJ | 1 |
| Murphy, D | 1 |
| Carachi, R | 1 |
| Furman, WL | 1 |
| McGregor, LM | 1 |
| McCarville, MB | 1 |
| Onciu, M | 1 |
| Davidoff, AM | 1 |
| Kovach, S | 1 |
| Hawkins, D | 1 |
| McPherson, V | 1 |
| Houghton, PJ | 1 |
| Billups, CA | 1 |
| Wu, J | 1 |
| Stewart, CF | 1 |
| Santana, VM | 1 |
| Scapolla, C | 1 |
| Bugnone, D | 1 |
| Profumo, A | 1 |
| Benatti, U | 1 |
| Damonte, G | 1 |
| Hase, T | 1 |
| Ohta, S | 1 |
| Tani, T | 1 |
| Mizukuro, T | 1 |
| Mekata, E | 1 |
| Naitoh, H | 1 |
| Shimadera, S | 1 |
| Fujino, S | 1 |
| Taga, T | 1 |
| Monsaingeon, M | 1 |
| Perel, Y | 2 |
| Simonnet, G | 1 |
| Corcuff, JB | 1 |
| Simon, T | 1 |
| Hero, B | 3 |
| Hunneman, DH | 6 |
| Berthold, F | 4 |
| PETRASEK, J | 2 |
| DUBOVSKY, J | 2 |
| SANKOFF, I | 1 |
| SOURKES, TL | 1 |
| WILLIAMS, CM | 3 |
| GREER, M | 1 |
| RUTHVEN, CR | 1 |
| SANDLER, M | 1 |
| Okazaki, T | 1 |
| Kohno, S | 1 |
| Mimaya, J | 2 |
| Hasegawa, S | 2 |
| Urushihara, N | 2 |
| Yoshida, A | 3 |
| Kawano, S | 1 |
| Kusafuka, J | 1 |
| Horikoshi, Y | 2 |
| Takashima, Y | 2 |
| Aoki, K | 2 |
| Hamazaki, M | 1 |
| Hashimoto, T | 1 |
| Koizumi, K | 1 |
| Nishina, T | 1 |
| Abe, K | 1 |
| Gripp, KW | 1 |
| Kawame, H | 1 |
| Viskochil, DH | 1 |
| Nicholson, L | 1 |
| Lorenzelli, L | 1 |
| Benvenuto, A | 1 |
| Adami, A | 1 |
| Guarnieri, V | 1 |
| Margesin, B | 1 |
| Mulloni, V | 1 |
| Vincenzi, D | 1 |
| Oue, T | 2 |
| Inoue, M | 2 |
| Yoneda, A | 2 |
| Kubota, A | 1 |
| Okuyama, H | 1 |
| Kawahara, H | 1 |
| Nishikawa, M | 2 |
| Nakayama, M | 2 |
| Kawa, K | 2 |
| Levreri, I | 1 |
| Caruso, U | 1 |
| Deiana, F | 1 |
| Buoncompagni, A | 1 |
| Marchese, N | 1 |
| Przkora, R | 1 |
| Perez-Canto, A | 1 |
| Ertel, W | 1 |
| Heyde, CE | 1 |
| Tajiri, S | 1 |
| Jiang, H | 1 |
| Jiang, Q | 1 |
| Liu, W | 1 |
| Feng, J | 1 |
| Barrette, S | 1 |
| Bernstein, ML | 4 |
| Leclerc, JM | 4 |
| Champagne, MA | 1 |
| Samson, Y | 1 |
| Brossard, J | 4 |
| Woods, WG | 12 |
| Strenger, V | 1 |
| Kerbl, R | 4 |
| Dornbusch, HJ | 1 |
| Ladenstein, R | 2 |
| Ambros, PF | 4 |
| Ambros, IM | 3 |
| Urban, C | 3 |
| Hirayama, M | 1 |
| Azuma, E | 1 |
| Araki, M | 1 |
| Komada, Y | 2 |
| Nakagawa, A | 1 |
| Mahoney, NR | 1 |
| Liu, GT | 1 |
| Menacker, SJ | 1 |
| Wilson, MC | 1 |
| Hogarty, MD | 1 |
| Nishio, N | 1 |
| Nara, T | 1 |
| Hamasaki, M | 1 |
| Rabady, DZ | 1 |
| Simon, JW | 1 |
| Lopasic, N | 1 |
| Knight, JA | 1 |
| Robertson, G | 1 |
| Wu, JT | 2 |
| Martin-Simmerman, P | 1 |
| Cohen, MD | 1 |
| Siddiqui, A | 1 |
| Mirkin, D | 1 |
| Provisor, A | 1 |
| Soldin, SJ | 3 |
| Ishiguro, Y | 1 |
| Ito, T | 1 |
| Nagaya, M | 1 |
| Yamada, N | 1 |
| Sugito, T | 1 |
| Chevallier, B | 1 |
| Testart, J | 1 |
| Bastit, P | 1 |
| Rajnherc, JR | 1 |
| van Gennip, AH | 2 |
| Abeling, NG | 2 |
| van der Zee, JM | 1 |
| Voûte, PA | 3 |
| Anton, AH | 1 |
| Crumrine, RS | 1 |
| Stern, RC | 1 |
| Izant, RJ | 1 |
| Kodama, K | 1 |
| Nakata, T | 1 |
| Aoyama, M | 1 |
| Binder, SR | 1 |
| Sivorinovsky, G | 1 |
| Lucarelli, C | 1 |
| Boniforti, L | 1 |
| Castello, MA | 1 |
| Clerico, A | 1 |
| Aubert, C | 1 |
| Janiaud, P | 1 |
| Rouge, F | 1 |
| Hansson, C | 1 |
| Rorsman, H | 1 |
| Rosengren, E | 1 |
| Tuchman, M | 14 |
| Crippin, PJ | 1 |
| Krivit, W | 5 |
| Yoshioka, M | 4 |
| Sakia, T | 1 |
| Tamura, Z | 2 |
| Crowley, JR | 1 |
| Couch, MW | 2 |
| Midgley, JM | 1 |
| Fornstedt, N | 1 |
| Heinemann, G | 1 |
| Schievelbein, H | 1 |
| Eberhagen, D | 1 |
| Rahlfs, V | 1 |
| Leiendecker-Foster, C | 1 |
| Freier, EF | 1 |
| Hill, JG | 2 |
| Lasson, U | 1 |
| LaBrosse, EH | 3 |
| Com-Nougué, C | 1 |
| Zucker, JM | 2 |
| Comoy, E | 2 |
| Bohuon, C | 2 |
| Lemerle, J | 1 |
| Schweisguth, O | 2 |
| Rosano, TG | 1 |
| Brown, HH | 1 |
| Meola, JM | 1 |
| Candito, M | 2 |
| Soler, C | 1 |
| Deville, A | 2 |
| Bekri, S | 1 |
| Chambon, P | 2 |
| Thyss, A | 3 |
| Koh, PS | 1 |
| Raffensperger, JG | 1 |
| Berry, S | 1 |
| Larsen, MB | 1 |
| Johnstone, HS | 1 |
| Chou, P | 1 |
| Luck, SR | 1 |
| Hammer, M | 1 |
| Cohn, SL | 2 |
| Stefănescu, AM | 1 |
| Suita, S | 5 |
| Zaizen, Y | 4 |
| Sera, Y | 5 |
| Takamatsu, H | 2 |
| Mizote, H | 2 |
| Ogami, H | 1 |
| Kurosaki, N | 2 |
| Ueda, K | 3 |
| Tasaka, H | 3 |
| Miyazaki, S | 2 |
| Yamamoto, K | 4 |
| Hayashi, Y | 4 |
| Ichikawa, M | 2 |
| Tanimura, M | 3 |
| Yoshioka, S | 1 |
| Hirata, T | 1 |
| Tatara, H | 1 |
| Matsuzaki, A | 1 |
| Ohi, R | 2 |
| Yaoita, S | 1 |
| Nakamura, M | 1 |
| Kikuchi, Y | 6 |
| Konno, T | 2 |
| Tsuchiya, S | 2 |
| Shiraishi, H | 1 |
| Schilling, FH | 2 |
| Erttmann, R | 1 |
| Strehl, S | 2 |
| Christiansen, H | 1 |
| Kovar, H | 2 |
| Kabisch, H | 1 |
| Treuner, J | 2 |
| Nishi, M | 16 |
| Miyake, H | 12 |
| Takeda, T | 20 |
| Yonemori, H | 2 |
| Hanai, J | 18 |
| Takasugi, N | 16 |
| Lemieux, B | 10 |
| Brisson, L | 3 |
| Brodeur, GM | 2 |
| Look, AT | 1 |
| Robison, LL | 5 |
| Shuster, JJ | 2 |
| Shimada, M | 3 |
| Iizuka, S | 1 |
| Hachitanda, Y | 2 |
| Ishimoto, K | 2 |
| Hata, J | 1 |
| Shimada, H | 2 |
| Mathieu, P | 4 |
| Philip, T | 4 |
| Greffe, J | 4 |
| Montegue, A | 1 |
| Lacroix, C | 1 |
| Fitzgibbon, MC | 1 |
| Tormey, WP | 1 |
| O'Meara, A | 1 |
| Tormey, W | 1 |
| FitzGerald, RJ | 1 |
| Fitzgibbon, M | 1 |
| Kenny, D | 1 |
| Akimaru, K | 1 |
| Shoji, T | 1 |
| Fukunaga, Y | 1 |
| Yamamoto, M | 1 |
| Ishizaki, R | 1 |
| Nomura, N | 1 |
| Bell, S | 5 |
| Parker, L | 5 |
| Craft, AW | 9 |
| Dale, G | 7 |
| McGill, AC | 6 |
| Seviour, J | 2 |
| Cole, M | 5 |
| Smith, J | 5 |
| Starz, I | 1 |
| Gadner, H | 2 |
| Huddart, SN | 2 |
| Muir, KR | 1 |
| Parkes, S | 1 |
| Mann, JR | 2 |
| Stevens, MC | 1 |
| Raafat, F | 1 |
| Seviour, JA | 5 |
| Tanabe, M | 1 |
| Yoshida, H | 1 |
| Ohnuma, N | 1 |
| Iwai, J | 1 |
| Takahashi, H | 1 |
| Rascher, W | 1 |
| Kremens, B | 1 |
| Wagner, S | 1 |
| Feth, F | 1 |
| Lang, RE | 1 |
| Naito, H | 2 |
| Queizán, A | 1 |
| García-Miguel, P | 1 |
| Belló, MJ | 1 |
| Castresana, JC | 1 |
| Rey, JA | 1 |
| Pestaña, A | 1 |
| Takeuchi, LA | 1 |
| Bernstein, M | 3 |
| Byrne, TD | 1 |
| Yamamoto, H | 1 |
| Yoshida, M | 1 |
| Urban, CE | 1 |
| Schnellauf, C | 1 |
| Sitzwohl, C | 1 |
| Lackner, H | 1 |
| Gleispach, H | 2 |
| Fauler, G | 2 |
| Rumpler, S | 1 |
| Spuller, E | 1 |
| Höfler, G | 1 |
| Amann, G | 1 |
| Kytir, J | 1 |
| Mutz, I | 1 |
| Chamberlain, J | 1 |
| Ohgami, H | 2 |
| Sugimoto, T | 1 |
| Kawakami, K | 3 |
| Tsuneyoshi, M | 1 |
| Yano, H | 1 |
| Akiyama, H | 3 |
| Ikeda, K | 4 |
| Eckschlager, T | 1 |
| Pilát, D | 1 |
| Kodet, R | 1 |
| Dahbiová, R | 1 |
| Stanková, J | 1 |
| Jasinská, J | 1 |
| Hrusák, O | 1 |
| Wassberg, E | 1 |
| Stridsberg, M | 1 |
| Christofferson, R | 1 |
| Chauvin, F | 3 |
| Frappaz, D | 3 |
| Lasset, C | 2 |
| Favrot, MC | 1 |
| Esteve, J | 2 |
| Thiesse, P | 1 |
| Combaret, V | 2 |
| Chauvot, P | 1 |
| Boschetti, R | 1 |
| David, L | 3 |
| Brunat-Mentigny, M | 2 |
| Kohnert, K | 1 |
| Lerch, H | 1 |
| Thelen, M | 1 |
| Jürgens, H | 1 |
| Schober, O | 1 |
| Vercherat, M | 1 |
| Favrot, M | 1 |
| Fouillat, V | 1 |
| Renaud, P | 1 |
| Leis, HJ | 1 |
| Huber, E | 1 |
| Schellauf, C | 1 |
| Cyr, D | 1 |
| Giguère, R | 5 |
| Prevel, A | 1 |
| Bergeron, C | 2 |
| Bory, C | 1 |
| Dia, S | 1 |
| Mathieu, M | 1 |
| Presto Elgstoen, KB | 1 |
| Jellum, E | 1 |
| Moritani, T | 1 |
| Shimanuki, Y | 1 |
| Ater, JL | 1 |
| Gardner, KL | 1 |
| Foxhall, LE | 1 |
| Therrell, BL | 1 |
| Bleyer, WA | 1 |
| Naoi, M | 1 |
| Maruyama, W | 1 |
| Kasamatsu, T | 1 |
| Dostert, P | 1 |
| Hirama, T | 1 |
| Shi, RZ | 1 |
| Ho, YP | 1 |
| Yeung, JH | 1 |
| Or, PM | 1 |
| To, KK | 1 |
| Lau, MW | 1 |
| Arumanayagam, M | 1 |
| Moe, PJ | 1 |
| Matsui, T | 1 |
| Taketo, A | 1 |
| Baillot, A | 1 |
| Schurr, P | 1 |
| Nerenz, A | 1 |
| Sander, J | 1 |
| Okuyama, C | 1 |
| Ushijima, Y | 1 |
| Watanabe, K | 1 |
| Sugihara, H | 1 |
| Nishimura, T | 1 |
| Kanesaka, Y | 1 |
| Tomita, K | 1 |
| Toyoda, Y | 1 |
| Takeuchi, M | 1 |
| Ohnuma, K | 1 |
| Nishi, T | 1 |
| Minard, V | 1 |
| Hartmann, O | 1 |
| Peyroulet, MC | 1 |
| Michon, J | 1 |
| Coze, C | 1 |
| Defachelle, AS | 1 |
| Lejars, O | 1 |
| Boutard, P | 1 |
| Leverger, G | 1 |
| Stephan, JL | 1 |
| Chastagner, P | 1 |
| Couillault, G | 1 |
| Devalck, C | 1 |
| Lutz, P | 1 |
| Mechinaud, F | 1 |
| Millot, F | 1 |
| Plantaz, D | 1 |
| Rialland, X | 1 |
| Rubie, H | 1 |
| Liu, YL | 1 |
| Cheng, AT | 1 |
| Chen, HR | 1 |
| Hsu, YP | 1 |
| Imura, K | 1 |
| Yagi, K | 1 |
| Morimoto, S | 1 |
| Gahr, M | 2 |
| Eldrup, E | 1 |
| Clausen, N | 2 |
| Scherling, B | 1 |
| Schmiegelow, K | 1 |
| Gao, RN | 1 |
| Weitzman, S | 1 |
| Bunin, G | 1 |
| Levy, I | 1 |
| Dougherty, G | 1 |
| Zuddas, A | 1 |
| Mancosu, C | 1 |
| Lilliu, V | 1 |
| Sorrentino, G | 1 |
| di Porzio, U | 1 |
| Cianchetti, C | 1 |
| Muskiet, FA | 3 |
| Fremouw-Ottevangers, DC | 1 |
| van der Meulen, J | 1 |
| Wolthers, BG | 2 |
| de Vries, JA | 1 |
| Wexler, B | 1 |
| Katzman, R | 1 |
| Wadman, SK | 1 |
| Ketting, D | 1 |
| Imashuku, S | 3 |
| Takada, H | 2 |
| Sawada, T | 6 |
| Nakamura, T | 1 |
| Kusunoki, T | 1 |
| Groen, A | 1 |
| Brewster, MA | 2 |
| Berry, DH | 2 |
| Morrisey, JL | 1 |
| Shihabi, ZK | 1 |
| Lamedica, G | 1 |
| Falcone, R | 1 |
| Canini, S | 1 |
| Melchert, HU | 1 |
| Hoffmeister, H | 1 |
| Peyrin, L | 1 |
| Cottet-Emard, JM | 1 |
| Claustre, B | 1 |
| Laug, WE | 1 |
| Siegel, SE | 1 |
| Shaw, KN | 1 |
| Landing, B | 1 |
| Baptista, J | 1 |
| Gutenstein, M | 1 |
| Jeuring, HJ | 1 |
| Nagel, GT | 1 |
| de Bruyn, HW | 1 |
| Orlowski, JP | 1 |
| Levin, HS | 1 |
| Price, RL | 1 |
| Dyment, PG | 1 |
| Moriarty, M | 1 |
| Yamazaki, T | 1 |
| Sakai, T | 1 |
| Verheyden, R | 2 |
| Ebinger, G | 2 |
| Maurus, R | 1 |
| Piöchl, E | 1 |
| Käser, H | 3 |
| Klein, H | 1 |
| Bray, PF | 1 |
| Myers, GG | 1 |
| Itano, M | 1 |
| Morita, S | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PHASE III MULTICENTRE TRIAL OF TREATMENT OF NEUROBLASTOMA IN CHILDREN AND ADOLESCENTS[NCT00002802] | Phase 3 | 500 participants (Anticipated) | Interventional | 1990-07-31 | Completed | ||
| European Low and Intermediate Risk Neuroblastoma Protocol[NCT01728155] | Phase 3 | 685 participants (Actual) | Interventional | 2011-01-01 | Completed | ||
| Clinical Research of Allogeneic Hematopoietic Stem Cell Transplantation for Treatment of Children With Stage 4/M Neuroblastoma: A Prospective, Single-arm, Phase II, Multi-center Trial[NCT05303727] | Phase 2 | 64 participants (Anticipated) | Interventional | 2022-08-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for homovanillic acid and Neuroblastoma
| Article | Year |
|---|---|
Neuroblastoma.
Topics: Biomarkers; Dopamine; Homovanillic Acid; Humans; Incidence; Mutation; N-Myc Proto-Oncogene Protein; | 2016 |
[Vanillylmandelic acid (VMA) and homovanillic acid (HVA)].
Topics: Adrenal Gland Neoplasms; Biomarkers; Chromatography, High Pressure Liquid; Chronic Disease; Depressi | 2005 |
[Abdominal sympathoma in adults. Apropos of 3 cases, with review of the literature].
Topics: Abdominal Neoplasms; Adult; Combined Modality Therapy; Female; Homovanillic Acid; Humans; Male; Neur | 1983 |
Paediatric reference ranges for urinary catecholamines/metabolites and their relevance in neuroblastoma diagnosis.
Topics: Adolescent; Catecholamines; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Infant; Infa | 1994 |
Screening for neuroblastoma: a review of the evidence.
Topics: Biomarkers; Europe; Homovanillic Acid; Humans; Incidence; Infant; Japan; Mass Screening; Neuroblasto | 1994 |
Screening for neuroblastoma.
Topics: Homovanillic Acid; Humans; Japan; Neuroblastoma; Vanilmandelic Acid | 1996 |
[Vanillylmandelic acid (VMA) and homovanillic acid (HVA)].
Topics: Adolescent; Child; Child, Preschool; Homovanillic Acid; Humans; Infant; Neuroblastoma; Pheochromocyt | 1999 |
Do children benefit from mass screening for neuroblastoma? Consensus Statement from the American Cancer Society Workshop on Neuroblastoma Screening.
Topics: Age Factors; Evaluation Studies as Topic; Homovanillic Acid; Humans; Infant; Infant, Newborn; Japan; | 1991 |
Screening for neuroblastoma.
Topics: Biomarkers, Tumor; Child, Preschool; Homovanillic Acid; Humans; Infant; Infant, Newborn; Mandelic Ac | 1991 |
N-myc oncogene and stage IV-S neuroblastoma. Preliminary observations on ten cases.
Topics: Female; Gene Amplification; Gene Expression; Histocompatibility Antigens Class I; Homovanillic Acid; | 1990 |
[Mass screening for early detection of neuroblastoma].
Topics: Homovanillic Acid; Humans; Mass Screening; Neuroblastoma; Vanilmandelic Acid | 1989 |
Pheochromocytoma: advances in diagnosis and treatment.
Topics: Adrenal Gland Neoplasms; Catecholamines; Child; Creatinine; Diagnosis, Differential; Epinephrine; Fe | 1972 |
12 trials available for homovanillic acid and Neuroblastoma
| Article | Year |
|---|---|
Interchangeability between 24-hour collection and single spot urines for vanillylmandelic and homovanillic acid levels in the diagnosis of neuroblastoma.
Topics: Biomarkers, Tumor; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Infant; Male; Neurobl | 2013 |
Development of a new biochemical test to diagnose and monitor neuroblastoma in Vietnam: homovanillic and vanillylmandelic acid by gas chromatography-mass spectrometry.
Topics: Adolescent; Biomarkers, Tumor; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; In V | 2014 |
A single-arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high-risk neuroblastoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Child; Child, P | 2012 |
Clinical usefulness of iodine-123-MIBG scintigraphy for patients with neuroblastoma detected by a mass screening survey.
Topics: 3-Iodobenzylguanidine; Biomarkers, Tumor; Female; Homovanillic Acid; Humans; Infant; Japan; Male; Ma | 2003 |
Long-term outcome in children with opsoclonus-myoclonus and ataxia and coincident neuroblastoma.
Topics: Abdominal Neoplasms; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Ataxia; Biomarkers; Child | 1994 |
A trial to discriminate spontaneous regression from non-regression cases during mass screening for neuroblastoma.
Topics: Adrenal Gland Neoplasms; False Negative Reactions; Homovanillic Acid; Humans; Japan; Mass Screening; | 1994 |
Screening infants for neuroblastoma: discovery of alkaptonuria in one case.
Topics: Alkaptonuria; Chromatography, High Pressure Liquid; Electrochemistry; Feasibility Studies; Homovanil | 1997 |
Spontaneous regression of localized neuroblastoma detected by mass screening.
Topics: Homovanillic Acid; Humans; Infant; Mass Screening; Neoplasm Regression, Spontaneous; Neuroblastoma; | 1998 |
Adverse outcome of infants with metastatic neuroblastoma, MYCN amplification and/or bone lesions: results of the French society of pediatric oncology.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disease-Free Survival; Female; Gene | 2000 |
Evaluation of catecholamine metabolites, mIBG scan, and bone marrow cytology as response markers in stage 4 neuroblastoma.
Topics: 3-Iodobenzylguanidine; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marro | 2001 |
Can a patient with neuroblastoma be diagnosed by a single urine sample collected randomly?
Topics: Homovanillic Acid; Humans; Infant; Neuroblastoma; Random Allocation; Vanilmandelic Acid | 1991 |
[Present status of neuroblastoma mass screening in Japan. Neuroblastoma-Committee of the Japanese Childhood Cancer Society].
Topics: Adolescent; Child; Child, Preschool; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans | 1990 |
219 other studies available for homovanillic acid and Neuroblastoma
| Article | Year |
|---|---|
Quantitation of Neuroblastoma Markers Homovanillic Acid (HVA) and Vanillylmandelic Acid (VMA) in Urine by Gas Chromatography-Mass Spectrometry (GC/MS).
Topics: Biomarkers; Catecholamines; Creatinine; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Hum | 2022 |
Optimising urinary catecholamine metabolite diagnostics for neuroblastoma.
Topics: Chromatography, Liquid; Homovanillic Acid; Humans; Metanephrine; Neuroblastoma; Tandem Mass Spectrom | 2023 |
Voltammetric Detection of Vanillylmandelic Acid and Homovanillic Acid Using Urea-Derivative-Modified Graphite Electrode.
Topics: Electrodes; Graphite; Homovanillic Acid; Humans; Neuroblastoma; Vanilmandelic Acid | 2023 |
Application of an LC-MS/MS Method for the Simultaneous Quantification of Homovanillic Acid and Vanillylmandelic Acid for the Diagnosis and Follow-Up of Neuroblastoma in 357 Patients.
Topics: Biological Assay; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Female; Follow-Up Stu | 2021 |
Excellent prognosis of patients with intermediate-risk neuroblastoma and residual tumor postchemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Combined Modality Therapy; Disease | 2018 |
Quantification of vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid in urine using a dilute-and-shoot and ultra-high pressure liquid chromatography tandem mass spectrometry method.
Topics: Biomarkers; Calibration; Carcinoid Tumor; Chromatography, High Pressure Liquid; Homovanillic Acid; H | 2018 |
Olive ingestion causing a false suspicion of relapsed neuroblastoma: A case of "oliveblastoma?"
Topics: Child, Preschool; Female; Homovanillic Acid; Humans; Neoplasm Recurrence, Local; Neuroblastoma; Olea | 2018 |
Analytical validation and clinical application of urinary vanillylmandelic acid and homovanillic acid by LC-MS/MS for diagnosis of neuroblastoma.
Topics: Adolescent; Biomarkers, Tumor; Child; Child, Preschool; Chromatography, Liquid; Female; Homovanillic | 2019 |
Analysis of vanillylmandelic acid and homovanillic acid by UPLC-MS/MS in serum for diagnostic testing for neuroblastoma.
Topics: Child, Preschool; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Infant; Neuroblas | 2013 |
Urinary homovanillic and vanillylmandelic acid in the diagnosis of neuroblastoma: report from the Italian Cooperative Group for Neuroblastoma.
Topics: Adolescent; Biomarkers, Tumor; Case-Control Studies; Child; Child, Preschool; Female; Homovanillic A | 2014 |
Long-term follow-up results of the observation program for neuroblastoma detected at 6-month mass screening.
Topics: Adrenal Gland Neoplasms; Age Factors; Child, Preschool; Female; Follow-Up Studies; Ganglioneuroblast | 2014 |
Reply to the letter: "Neonatal screening for Menkes disease using urine HVA/VMA ratio".
Topics: Homovanillic Acid; Humans; Infant; Infant, Newborn; Menkes Kinky Hair Syndrome; Neonatal Screening; | 2016 |
Neonatal screening for Menkes disease using urine HVA/VMA ratio.
Topics: Homovanillic Acid; Humans; Infant; Infant, Newborn; Menkes Kinky Hair Syndrome; Neonatal Screening; | 2016 |
Clinical validation of urine 3-methoxytyramine as a biomarker of neuroblastoma and comparison with other catecholamine-related biomarkers.
Topics: Biomarkers, Tumor; Case-Control Studies; Child; Child, Preschool; Chromatography, High Pressure Liqu | 2017 |
A Newborn with Distended Abdomen.
Topics: Biopsy; Diagnosis, Differential; Homovanillic Acid; Humans; Infant, Newborn; Liver Neoplasms; Male; | 2016 |
A novel l-leucine modified Sol-Gel-Carbon electrode for simultaneous electrochemical detection of homovanillic acid, dopamine and uric acid in neuroblastoma diagnosis.
Topics: Dopamine; Electrodes; Homovanillic Acid; Humans; Leucine; Neuroblastoma; Uric Acid | 2017 |
HPLC-mass spectrometry method for quantitative detection of neuroendocrine tumor markers: vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid.
Topics: Biomarkers, Tumor; Calibration; Carcinoid Tumor; Chromatography, High Pressure Liquid; Homovanillic | 2008 |
Diagnostic and prognostic markers in infants with disseminated neuroblastoma: a retrospective analysis from the Italian Cooperative Group for Neuroblastoma.
Topics: Biomarkers; Chromosomes, Human, Pair 1; Ferritins; Genetic Markers; Homovanillic Acid; Humans; Infan | 2009 |
Simultaneous analysis of neuroendocrine tumor markers by HPLC-electrochemical detection.
Topics: Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Child; Child, Preschool; Chromatography, High Pre | 2009 |
A prospective study of a long-term follow-up of an observation program for neuroblastoma detected by mass screening.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Combined Modality Therapy; Disease Progression; Female; Fo | 2010 |
Quantitation of homovanillic acid (HVA) and vanillylmandelic acid (VMA) in urine using gas chromatography-mass spectrometry (GC/MS).
Topics: Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Neuroblastoma; Reference Standards; | 2010 |
Urine catecholamine levels as diagnostic markers for neuroblastoma in a defined population: implications for ophthalmic practice.
Topics: Adolescent; Biomarkers; Catecholamines; Child; Cohort Studies; Female; Homovanillic Acid; Humans; In | 2010 |
Age-related medical decision limits for urinary free (unconjugated) metadrenalines, catecholamines and metabolites in random urine specimens from children.
Topics: Adolescent; Age Factors; Catecholamines; Child, Preschool; Decision Making; Diagnosis, Differential; | 2011 |
Identification and structural characterization by LC-ESI-IONTRAP and LC-ESI-TOF of some metabolic conjugation products of homovanillic acid in urine of neuroblastoma patients.
Topics: Chromatography, Liquid; Homovanillic Acid; Humans; Ions; Models, Molecular; Neuroblastoma; Spectrome | 2012 |
Outcome of infants with neuroblastoma detected by mass screening and surgically treated in Shiga Prefecture, Japan: what is the role of surgery?
Topics: Adrenal Gland Neoplasms; Biomarkers, Tumor; Female; Homovanillic Acid; Humans; Infant; Japan; Male; | 2002 |
Comparative values of catecholamines and metabolites for the diagnosis of neuroblastoma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Chromatography, High Pressure Liquid; Homovanillic Acid; Hu | 2003 |
Tumour markers are poor predictors for relapse or progression in neuroblastoma.
Topics: Adolescent; Biomarkers, Tumor; Bone Marrow Neoplasms; Child; Child, Preschool; Clinical Trials as To | 2003 |
[On the excretion of 3-methoxy-4-hydroxyphenylacetic acid (homovanillic acid) in neuroblastoma and other neural tumors].
Topics: Body Fluids; Homovanillic Acid; Humans; Neuroblastoma; Phenylacetates | 1962 |
[Elimination of 3-methoxy-4-hydroxyphenylacetic acid (homovanillic acid). II. Clinical applications].
Topics: Homovanillic Acid; Humans; Neuroblastoma; Paraganglioma; Phenylacetates; Pheochromocytoma | 1963 |
[Isolation of 3-methoxy-4-hydroxymandelic acid (vanillin-mandelic acid) and 3-methoxy-4-hydroxphenylacetic acid (homovanillic acid) in tumors of the sympathoadrenal system].
Topics: Benzaldehydes; Homovanillic Acid; Humans; Mandelic Acids; Neuroblastoma; Paraganglioma; Phenylacetat | 1962 |
Determination by thin-layer chromatography of urinary homovanillic acid in normal and disease states.
Topics: Chorea; Chromatography, Thin Layer; Ganglioneuroma; Hepatolenticular Degeneration; Homovanillic Acid | 1963 |
Homovanillic acid and vanilmandelic acid in diagnosis of neuroblastoma.
Topics: Biological Assay; Homovanillic Acid; Humans; Mandelic Acids; Neuroblastoma; Phenylacetates; Tyrosine | 1963 |
ESTIMATION OF HOMOVANILLIC ACID IN URINE.
Topics: Chromatography; Clinical Laboratory Techniques; Colorimetry; Dopamine; Ganglioneuroma; Homovanillic | 1964 |
Neuroblastoma detected by mass screening: the Tumor Board's role in its treatment.
Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Creatinine; Follow-Up Studi | 2004 |
Elevated catecholamine metabolites in patients with Costello syndrome.
Topics: Abnormalities, Multiple; Biomarkers; Child; Child, Preschool; Female; Genetic Predisposition to Dise | 2004 |
Development of a gas chromatography silicon-based microsystem in clinical diagnostics.
Topics: Biomarkers, Tumor; Chromatography, Gas; Electrochemistry; Equipment Design; Equipment Failure Analys | 2005 |
Profile of neuroblastoma detected by mass screening, resected after observation without treatment: results of the Wait and See pilot study.
Topics: Adrenal Gland Neoplasms; Aneuploidy; Child, Preschool; Female; Homovanillic Acid; Humans; Infant; Ma | 2005 |
The secretion of ibuprofen metabolites interferes with the capillary chromatography of urinary homovanillic acid and 4-hydroxy-3-methoxymandelic acid in neuroblastoma diagnosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catecholamines; Child; Child, Preschool; Chromatography, Ga | 2005 |
Ganglioneuroma : primary tumor or maturation of a suspected neuroblastoma?
Topics: Adolescent; Child; Diagnosis, Differential; Female; Ganglioneuroma; Homovanillic Acid; Humans; Nervo | 2006 |
Parkin suppresses the expression of monoamine oxidases.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; B-Lymphocytes; Binding Sites; Cell Line, Transformed; Cell | 2006 |
Treatment complications in children diagnosed with neuroblastoma during a screening program.
Topics: Homovanillic Acid; Humans; Infant; Infant, Newborn; Mass Screening; Neoplasm Staging; Neuroblastoma; | 2006 |
Diagnostic and prognostic impact of urinary catecholamines in neuroblastoma patients.
Topics: Adolescent; Catecholamines; Child; Child, Preschool; Dopamine; Female; Homovanillic Acid; Humans; In | 2007 |
Evidence of graft-versus-tumor effect in refractory metastatic neuroblastoma.
Topics: Antigens, CD; Bone Marrow Cells; Child; Cyclosporine; Female; Graft vs Tumor Effect; Homovanillic Ac | 2006 |
Pediatric horner syndrome: etiologies and roles of imaging and urine studies to detect neuroblastoma and other responsible mass lesions.
Topics: Abdominal Neoplasms; Adolescent; Anisocoria; Blepharoptosis; Bone Neoplasms; Brain Neoplasms; Child; | 2006 |
Results for 79 patients with neuroblastoma detected through mass screening at 6 months of age in a single institute.
Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Homovani | 2006 |
Pediatric horner syndrome: etiologies and roles of imaging and urine studies to detect neuroblastoma and other responsible mass lesions.
Topics: Abdominal Neoplasms; Adolescent; Anisocoria; Blepharoptosis; Bone Neoplasms; Brain Neoplasms; Chroma | 2007 |
The chemical basis and specificity of the nitrosonaphthol reaction.
Topics: Amino Acid Metabolism, Inborn Errors; Carcinoid Tumor; Chemical Phenomena; Chemistry; Guaiacol; Homo | 1983 |
Calcification and uptake of Tc-99m diphosphonates in neuroblastomas: concise communication.
Topics: Abdominal Neoplasms; Bone and Bones; Calcinosis; Diphosphonates; Etidronic Acid; Female; Homovanilli | 1984 |
High-performance liquid chromatography: applications in a children's hospital.
Topics: Adolescent; Anticonvulsants; Catecholamines; Child; Child, Preschool; Chromatography, High Pressure | 1982 |
Nervous system-specific enolase in serum as a marker for neuroblastoma.
Topics: Child; Child, Preschool; Female; Homovanillic Acid; Humans; Immunoenzyme Techniques; Infant; Infant, | 1983 |
Cystathioninuria in patients with neuroblastoma.
Topics: Adolescent; Child; Child, Preschool; Cystathionine; Dihydroxyphenylalanine; Female; Homovanillic Aci | 1984 |
Inhibition of catecholamine biosynthesis by carbidopa and metyrosine in neuroblastoma.
Topics: alpha-Methyltyrosine; Carbidopa; Catecholamines; Child, Preschool; Dihydroxyphenylalanine; Dopamine; | 1983 |
Direct determination of urinary vanillylmandelic acid and homovanillic acid by high-performance liquid chromatography on an anion-exchange column.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrochemistry; Female; Homova | 1984 |
Measurement of urinary vanilmandelic acid and homovanillic acid by high-performance liquid chromatography with electrochemical detection following extraction by ion-exchange and ion-moderated partition.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrochemistry; Homovanillic A | 1984 |
Mass-spectrometry determination of urinary catecholamine metabolites children with neuroblastoma.
Topics: Catecholamines; Child; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Neuroblastom | 1983 |
Melanogenesis in cultured human neuroblastomas.
Topics: Animals; Cell Line; Cysteinyldopa; Dihydroxyphenylalanine; Female; Homovanillic Acid; Humans; Male; | 1980 |
Capillary gas-chromatographic determination of urinary homovanillic acid and vanillylmandelic acid.
Topics: Adolescent; Adrenal Gland Neoplasms; Child; Child, Preschool; Chromatography, Gas; Female; Homovanil | 1983 |
Simple method for the determination of homovanillic acid and vanillylmandelic acid in urine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Human | 1982 |
Increased excretion of m-Hydroxyphenylglycol and m-Hydroxymandelic acid in neuroblastoma.
Topics: Adult; Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Glycols; Homovanillic | 1982 |
High-performance liquid chromatographic determination of homovanillic acid in urine using Sephadex G-10 for isolation.
Topics: Adult; Child; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Neuroblastoma; Phenyl | 1981 |
[The influence of different diets and smoking on the clinical chemical diagnosis of pheochromocytoma, neuroblastoma, and carcinoid syndrome (author's transl)].
Topics: Adrenal Gland Neoplasms; Adult; Diagnosis, Differential; Epinephrine; Feeding Behavior; Homovanillic | 1981 |
Improved simultaneous gas-chromatographic analysis for homovanillic acid and vanillylmandelic acid in urine.
Topics: Adolescent; Child; Chromatography, Gas; Homovanillic Acid; Humans; Neuroblastoma; Phenylacetates; Te | 1981 |
Simultaneous liquid-chromatographic analysis for 4-hydroxy-3-methoxymandelic acid and 4-hydroxy-3-methoxyphenylacetic acid in urine.
Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Neuroblast | 1980 |
[Thoracic neuroblastoma].
Topics: Child; Dopamine; Homovanillic Acid; Humans; Neuroblastoma; Prognosis; Thoracic Neoplasms; Vanilmande | 1980 |
Urinary excretion of 3-methoxy-4-hydroxymandelic acid and 3-methoxy-4-hydroxyphenylacetic acid by 288 patients with neuroblastoma and related neural crest tumors.
Topics: Adolescent; Adult; Child; Child, Preschool; Homovanillic Acid; Humans; Infant; Nervous System Neopla | 1980 |
Liquid-chromatographic assay for urinary homovanillic acid, with fluorescent detection.
Topics: Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Neuroblastoma; Phenylacetates; Refe | 1981 |
Liquid-chromatographic analysis for urinary 4-hydroxy-3-methoxymandelic acid and 4-hydroxy-3-methoxyphenylacetic acid, and its use in investigation of neural crest tumors.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Child; Child, Preschool; Chromatography, Liquid; Female; | 1981 |
Urinary excretion of methylated catecholamine metabolites in a child with neuroblastoma maturing into ganglioneuroma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Dopamine; Ganglioneuroma; Homovanillic Acid; Humans; Infant | 1996 |
An improvement of the endocrine diagnosis by high-performance liquid chromatography.
Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Chromatography, High Pressure Liquid; Chromatography | 1993 |
Neuroblastoma in infants aged less than 6 months: is more aggressive treatment necessary? A report from the Pediatric Oncology Study Group of the Kyushu area.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Female; Ganglioneuroblastoma; Hom | 1995 |
Mass screening and age-specific incidence of neuroblastoma in Saitama Prefecture, Japan.
Topics: Adolescent; Age Factors; Chi-Square Distribution; Child; Child, Preschool; Creatinine; Homovanillic | 1995 |
Role of ultrasound in managing neuroblastoma detected by mass screening: a proposed ultrasonographic grading for children with neuroblastoma.
Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Creatinine; Female; Homovanillic Acid | 1995 |
Problems of neuroblastoma screening for 6 month olds and results of second screening for 18 month olds.
Topics: Adrenal Gland Neoplasms; Age Distribution; Child; Child, Preschool; Chromatography, High Pressure Li | 1995 |
Screening for neuroblastoma.
Topics: Abdominal Neoplasms; Biomarkers, Tumor; Homovanillic Acid; Humans; Infant; Mass Screening; Neuroblas | 1994 |
Screening for neuroblastoma (NB) in North America: the Quebec Project.
Topics: Chromatography, Thin Layer; False Negative Reactions; Gas Chromatography-Mass Spectrometry; Homovani | 1994 |
Effects of mass screening for neuroblastoma and the presumptive natural history of this tumor.
Topics: Adolescent; Child; Child, Preschool; Homovanillic Acid; Humans; Incidence; Infant; Infant, Newborn; | 1994 |
One hundred neuroblastomas detected through a mass screening system in Japan.
Topics: Ferritins; Genes, myc; Homovanillic Acid; Humans; Infant; Japan; Mass Screening; Neoplasm Staging; N | 1994 |
A simple coloured-paper thin-layer chromatography test as a backup procedure for vanillylmandelic acid and homovanillic acid evaluation in a neuroblastoma screening program.
Topics: Chromatography, High Pressure Liquid; Chromatography, Paper; Chromatography, Thin Layer; Electrochem | 1993 |
Interpretation of random urinary catecholamines and their metabolites in neuroblastoma.
Topics: Catecholamines; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Infant; Infant, Newborn; | 1994 |
Amplification of N-myc gene and increase of urinary VMA and HVA in patients with neuroblastic tumors.
Topics: Child, Preschool; Female; Ganglia, Sympathetic; Gene Amplification; Genes, myc; Homovanillic Acid; H | 1994 |
False positive results in a neuroblastoma screening programme.
Topics: Creatinine; England; False Positive Reactions; Female; Homovanillic Acid; Humans; Infant; Male; Mass | 1994 |
Neuroblastoma with N-myc amplification detected by urine: mass screening in infants after the sixth month of life.
Topics: Diploidy; Gene Amplification; Genes, myc; Homovanillic Acid; Humans; Infant; Mass Screening; Neurobl | 1993 |
Neuroblastoma: a 32-year population-based study--implications for screening.
Topics: Abdominal Neoplasms; Adolescent; Adrenal Gland Neoplasms; Age Factors; Child; Child, Preschool; Comb | 1993 |
Creatinine related reference ranges for urinary homovanillic acid and vanillylmandelic acid at 6 months of age.
Topics: Creatinine; Female; Homovanillic Acid; Humans; Infant; Male; Mass Screening; Neuroblastoma; Predicti | 1993 |
Imaging of neuroblastoma in patients identified by mass screening using urinary catecholamine metabolites.
Topics: Adrenal Gland Neoplasms; Female; Homovanillic Acid; Humans; Infant; Magnetic Resonance Imaging; Male | 1993 |
Serial measurements of neuropeptide Y in plasma for monitoring neuroblastoma in children.
Topics: Adolescent; Biomarkers, Tumor; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Infant; M | 1993 |
Failure to detect dopaminergic neuroblastoma in a mass-screening system.
Topics: Age Factors; Child; Child, Preschool; Dopamine; Female; Homovanillic Acid; Humans; Infant; Male; Mas | 1995 |
[Sensibility and specificity of N-myc oncogene with respect to other prognostic factors in 15 neuroblastomas].
Topics: Brain; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 1; Ferritins; Gene Amplificati | 1995 |
Screening for neuroblastoma in North America. Preliminary results of a pathology review from the Quebec Project.
Topics: Age Factors; Cohort Studies; Disease-Free Survival; Female; Follow-Up Studies; Homovanillic Acid; Hu | 1995 |
Laparoscopic surgery for neuroblastoma identified by mass screening.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Female; Follow-Up Studies; Homovanillic Acid; Humans; Infant | 1996 |
[5 years neuroblastoma screening in Austria: rate of participation, results and a comparison with other screening areas].
Topics: Austria; Cross-Sectional Studies; Female; Homovanillic Acid; Humans; Incidence; Infant; Male; Mass S | 1996 |
Mass screening for neuroblastoma: quo vadis? A 9-year experience from the Pediatric Oncology Study Group of the Kyushu area in Japan.
Topics: Adolescent; Adrenal Gland Neoplasms; Biomarkers, Tumor; Biopsy; Child; Child, Preschool; Combined Mo | 1996 |
DNA ploidy in neuroblastoma.
Topics: Catecholamines; Child, Preschool; DNA, Neoplasm; Female; Homovanillic Acid; Humans; Infant; Male; Ne | 1996 |
Plasma levels of chromogranin A are directly proportional to tumour burden in neuroblastoma.
Topics: Adrenal Gland Neoplasms; Animals; Biomarkers, Tumor; Chromogranin A; Chromogranins; Female; Homovani | 1996 |
Screening for neuroblastoma in France: methodological aspects and preliminary observations.
Topics: Child, Preschool; Chromatography, High Pressure Liquid; False Negative Reactions; False Positive Rea | 1997 |
[Follow up control of stage IV neuroblastoma: 123I-MIBG scintigraphy, bone scintigraphy and catecholamine metabolites].
Topics: 3-Iodobenzylguanidine; Bone and Bones; Bone Neoplasms; Brain Neoplasms; Catecholamines; Child; Child | 1996 |
A 5-year (1990-1994) neuroblastoma screening feasibility study in France. Methodology and preliminary observations.
Topics: Chromatography, High Pressure Liquid; Creatinine; False Negative Reactions; False Positive Reactions | 1996 |
Mass-screening of neuroblastoma using urine from infants by high-performance liquid chromatographic method: results of first (6th month) and second (14th month) screening.
Topics: Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Humans; Infant; Japan; Male; Mass S | 1997 |
Natural history of neuroblastoma found by mass screening.
Topics: Homovanillic Acid; Humans; Incidence; Infant; Mass Screening; Neuroblastoma; Remission, Spontaneous; | 1997 |
Mass screening for neuroblastoma and mortality in birth cohorts.
Topics: Adolescent; Biomarkers, Tumor; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cohort | 1997 |
Determination of homovanillic acid and vanillylmandelic acid in neuroblastoma screening by stable isotope dilution GC-MS.
Topics: Calibration; Carbon Isotopes; Chromatography, High Pressure Liquid; Creatinine; Deuterium; Gas Chrom | 1997 |
Stability of urinary HVA and VMA on filter paper.
Topics: Homovanillic Acid; Humans; Infant, Newborn; Neonatal Screening; Neuroblastoma; Vanilmandelic Acid | 1997 |
Capillary electrophoresis for diagnosis of metabolic disease.
Topics: Alkaptonuria; Electrophoresis, Capillary; Galactosemias; Homogentisic Acid; Homovanillic Acid; Human | 1997 |
Neuroblastoma screening in the United States: results of the Texas Outreach Program for neuroblastoma screening.
Topics: Enzyme-Linked Immunosorbent Assay; Feasibility Studies; Female; Homovanillic Acid; Humans; Infant; M | 1998 |
Oxidation of N-methyl(R)salsolinol: involvement to neurotoxicity and neuroprotection by endogenous catechol isoquinolines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Corpus Striatum; Cycloheximide; Disease Model | 1998 |
Mass screening for neuroblastoma targeting children age 14 months in Sapporo City: a preliminary report.
Topics: Cross-Sectional Studies; Dopamine; Female; Homovanillic Acid; Humans; Incidence; Infant; Japan; Male | 1998 |
Development of an enzyme-linked immunosorbent assay with monoclonal antibody for quantification of homovanillic acid [corrected] in human urine samples.
Topics: Adolescent; Animals; Antibodies, Monoclonal; Child; Child, Preschool; Chromatography, High Pressure | 1998 |
Screening for neuroblastoma and age-specific incidence.
Topics: Adolescent; Child; Child, Preschool; Homovanillic Acid; Humans; Incidence; Infant; Infant, Newborn; | 1999 |
Induction of catecholamine synthesis in human neuroblastoma cells by replication inhibitors and sodium butyrate.
Topics: Amanitins; Antineoplastic Agents; Butyrates; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replicatio | 1999 |
Which cases are found and missed by neuroblastoma screening at 1 year? Results from the 1992 to 1995 study in three Federal States of Germany.
Topics: Biomarkers, Tumor; Chromatography; Female; Germany; Homovanillic Acid; Humans; Incidence; Infant; Ma | 1999 |
[Iodine-123-MIBG scintigraphy in neuroblastoma; relationship between the intensity of uptake and tumor characteristics].
Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Biomarkers; Catecholamines; Child; Child, Preschool; | 1999 |
Natural course of neuroblastoma detected by mass screening: s 5-year prospective study at a single institution.
Topics: Abdominal Neoplasms; Adrenal Gland Neoplasms; Biomarkers, Tumor; Female; Homovanillic Acid; Humans; | 2000 |
Simultaneous HPLC of twelve monoamines and metabolites shows neuroblastoma cell line releases HVA and HIAA.
Topics: Biogenic Monoamines; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Hydroxyindolea | 2000 |
Observation of untreated patients with neuroblastoma detected by mass screening: a "wait and see" pilot study.
Topics: Adrenal Gland Neoplasms; Biomarkers, Tumor; Chemotherapy, Adjuvant; Disease Progression; Follow-Up S | 2001 |
Evaluation of plasma 3,4-dihydroxyphenylacetic acid (DOPAC) and plasma 3,4-dihydroxyphenylalanine (DOPA) as tumor markers in children with neuroblastoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Biomarkers, Tumor; Case-Control Studies; Child; C | 2001 |
Screening of infants and mortality due to neuroblastoma.
Topics: Canada; Case-Control Studies; Catecholamines; Child; Child, Preschool; Female; Follow-Up Studies; Ho | 2002 |
Stephen L. Gans overseas lecture. Mass screening for neuroblastoma in Japan: lessons learned and future directions.
Topics: Adrenal Gland Neoplasms; Child, Preschool; Homovanillic Acid; Humans; Incidence; Infant; Japan; Mass | 2002 |
6R-Tetrahydrobiopterin induces dopamine synthesis in a human neuroblastoma cell line, LA-N-1. A cellular model of DOPA-responsive dystonia.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Biopterins; Dopamine; Dopamine Antagonists; Dys | 2002 |
Catecholamine metabolism in neuroblastoma.
Topics: Catecholamines; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Metho | 1976 |
Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adult; Aging; Child; Child, Presch | 1978 |
Effects of dibutyryl cyclic AMP on tyrosine uptake and metabolism in neuroblastoma cultures.
Topics: Animals; Bucladesine; Cell Line; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Hydroxylation; | 1975 |
Gas chromatographic determination of urinary vanilglycolic acid, vanilglycol, vanilacetic acid and vanillactic acid-chemical parameters for the diagnosis of neurogenic tumours and the evaluation of their treatment.
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Chromatography, Thin Layer; Creatin | 1976 |
Studies on tyrosine hydroxylase in neuroblastoma in relation to urinary levels of catecholamine metabolites.
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Bone Neoplasms; Chromatography, Paper; Chromato | 1975 |
Biochemical activity in the metastatic lesions of neuroblastoma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans; Neopl | 1975 |
Urinary excretion of conjugated homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid by persons on their usual diet and patients with neuroblastoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Animals; Child; Child, Preschool; Glucuronidase; Homovanillic | 1979 |
Serial studies of serum dopamine-B-hydroxylase and urinary vanillylmandelic and homovanillic acids in neuroblastoma.
Topics: Child; Child, Preschool; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Humans; Infant; Male; | 1979 |
Assay of 4-hydroxy-3-methoxyphenylacetic (homovanillic) acid by liquid chromatography with electrochemical detection.
Topics: Adult; Chromatography, Liquid; Electrochemistry; Homovanillic Acid; Humans; Neuroblastoma; Parkinson | 1979 |
[Characteristics of urinary excretion of vanilmandelic and homovanillic acids in cases of neuroblastoma during therapy].
Topics: Adolescent; Child; Child, Preschool; Chromatography, Thin Layer; Homovanillic Acid; Humans; Infant; | 1978 |
More on gas-liquid chromatographic determination of homovanillic and vanillylmandelic acids in urine from cases of neuroblastoma.
Topics: Chromatography, Gas; Homovanillic Acid; Humans; Methods; Neuroblastoma; Phenylacetates; Vanilmandeli | 1978 |
Studies on urinary DOPAC in man by means of a sensitive automated procedure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Addison Disease; Adrenal Gland Neoplasms; Adult; Aged; Autoanalysis; | 1978 |
Initial urinary catecholamine metabolite concentrations and prognosis in neuroblastoma.
Topics: Adrenal Gland Neoplasms; Aminobutyrates; Catecholamines; Child, Preschool; Cystathionine; Female; Ho | 1978 |
Mass-fragmentographic determination of catecholamine metabolites in amniotic fluid and its possible clinical usefulness.
Topics: Adrenal Gland Neoplasms; Amniotic Fluid; Catecholamines; Creatinine; Female; Fetal Diseases; Gas Chr | 1978 |
Normal urinary excretion of catecholamine catabolites in children with retinoblastoma.
Topics: Catecholamines; Child, Preschool; Eye Neoplasms; Female; Homovanillic Acid; Humans; Male; Metanephri | 1978 |
Urinary 3-methoxy-4-hydroxyphenylacetic (homovanillic) and 3-methoxy-4-hydroxymandelic (vanillylmandelic) acids: gas-liquid chromatographic methods and experience with 13 cases of neuroblastoma.
Topics: Child; Chromatography, Gas; Homovanillic Acid; Humans; Neuroblastoma; Phenylacetates; Vanilmandelic | 1977 |
Urinary levels of vanilmandelic acid and homovanillic acid determined by high-speed liquid chromatography.
Topics: Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Diet; Homovanillic Acid; Human | 1976 |
Para-O-methylation of the catecholamines in neuroblastoma.
Topics: Catecholamines; Child; Chromatography, Thin Layer; Homovanillic Acid; Humans; Lactates; Neuroblastom | 1975 |
Thin-layer chromatography for diagnosis of secreting neuroblastoma.
Topics: Adolescent; Catecholamines; Child; Child, Preschool; Chromatography, Thin Layer; Female; Homovanilli | 1975 |
Excretion of catecholamines in relatives of patients with familial neuroblastoma.
Topics: Adult; Age Factors; Aged; Catecholamines; Child; Child, Preschool; Dopamine; Epinephrine; Female; Ho | 1976 |
Letter: Reliable chemical diagnosis of neuroblastoma better than screening.
Topics: Homovanillic Acid; Humans; Neuroblastoma; Phenylacetates; Vanilmandelic Acid | 1976 |
Screening for neuroblastoma in the north of England.
Topics: Creatinine; England; False Negative Reactions; False Positive Reactions; Feasibility Studies; Female | 1992 |
Mass screening for neuroblastoma in Miyagi Prefecture.
Topics: Biomarkers, Tumor; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Infant; Japan; M | 1992 |
Cystic neuroblastoma.
Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Cysts; Diagnosis, Di | 1992 |
Serum vanillylmandelic acid/homovanillic acid contributes to prognosis estimation in patients with localised but not with metastatic neuroblastoma.
Topics: Biomarkers, Tumor; Child; Child, Preschool; Homovanillic Acid; Humans; Infant; Neoplasm Staging; Neu | 1992 |
Screening for neuroblastoma in North America. 2-year results from the Quebec Project.
Topics: Algorithms; Biomarkers, Tumor; Follow-Up Studies; Gas Chromatography-Mass Spectrometry; Homovanillic | 1992 |
Screening for neuroblastoma in the northern region of England. Laboratory aspects.
Topics: Biomarkers, Tumor; England; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Inciden | 1992 |
Mass screening of neuroblastoma in Sapporo City, Japan.
Topics: Biomarkers, Tumor; Homovanillic Acid; Humans; Incidence; Infant; Japan; Mass Screening; Neoplasm Sta | 1992 |
A pilot study of screening for neuroblastoma in the north of England.
Topics: England; Female; Homovanillic Acid; Humans; Infant; Male; Mass Screening; Neuroblastoma; Pilot Proje | 1992 |
Continued remission in children with neuroblastoma despite elevations of urinary catecholamine metabolites.
Topics: Child, Preschool; Female; Homovanillic Acid; Humans; Infant; Male; Neuroblastoma; Prospective Studie | 1992 |
Serial measurement of urinary VMA and HVA levels from one infant: a study for neuroblastoma mass screening.
Topics: Chromatography, High Pressure Liquid; Circadian Rhythm; Creatinine; Homovanillic Acid; Humans; Infan | 1992 |
Methylated catecholamine metabolites for diagnosis of neuroblastoma.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Dopamine; Epinephrine; Female; Homovanill | 1992 |
Measurement of dopamine, HVA and HMMA in untimed urine samples: establishment of age-related reference data in children.
Topics: Adolescent; Age Factors; Catecholamines; Child; Child, Preschool; Chromatography, Gas; Chromatograph | 1992 |
Treatment for stage III-IV neuroblastoma patients: initial response to chemotherapy evaluated by biochemical parameters.
Topics: Abdominal Neoplasms; Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Bone N | 1991 |
Presumed iris metastasis from abdominal neuroblastoma.
Topics: Homovanillic Acid; Humans; Infant; Iris Neoplasms; Male; Neuroblastoma; Retroperitoneal Neoplasms; V | 1991 |
[Screening for neuroblastoma in infants aged 6 months. A method of testing].
Topics: Denmark; Homovanillic Acid; Humans; Mass Screening; Neuroblastoma; Prognosis; Vanilmandelic Acid | 1991 |
Mass screening in Japan increased the detection of infants with neuroblastoma without a decrease in cases in older children.
Topics: Age Factors; Chromatography, High Pressure Liquid; Ganglioneuroma; Homovanillic Acid; Humans; Infant | 1991 |
Different genomic and metabolic patterns between mass screening-positive and mass screening-negative later-presenting neuroblastomas.
Topics: Adrenal Gland Neoplasms; Age Factors; Biomarkers, Tumor; Blotting, Southern; Child, Preschool; DNA P | 1991 |
Determination of urinary vanillactic acid and plasma dihydroxyphenylalanine as markers of non-secreting neuroblastoma by high-performance liquid chromatography with electrochemical detection.
Topics: Adolescent; Biomarkers, Tumor; Child; Child, Preschool; Chromatography, High Pressure Liquid; Diet; | 1991 |
Screening for neuroblastoma in North America--preliminary results from the Quebec project.
Topics: Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Infant; | 1991 |
Evaluation of a rapid and reliable method for mass screening for neuroblastoma in infants.
Topics: Catecholamines; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Homovanillic Acid; | 1991 |
Results of mass screening for neuroblastoma in Sapporo, Japan.
Topics: Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Infant; Japan; Mass Screening; Neop | 1991 |
Simultaneous determination of vanillylmandelic acid, homovanillic acid and creatinine in urine by reversed-phase ion-pair chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Creatinine; Homovanillic Acid; H | 1990 |
Screening for neuroblastoma at 3 weeks of age: methods and preliminary results from the Quebec Neuroblastoma Screening Project.
Topics: Chromatography, Gas; Chromatography, Thin Layer; False Positive Reactions; Homovanillic Acid; Humans | 1990 |
Fluctuation in the concentrations of vanillylmandelic acid and homovanillic acid in mass screening for neuroblastoma.
Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; False Negative Reactions; Homovanilli | 1990 |
Histological, immunohistochemical, and chromosomal studies on non-adrenal neuroblastomas without increased excretion of catecholamines and their metabolites in urine.
Topics: Catecholamines; Child; Chromosome Banding; Chromosomes; Cytoplasm; Dopamine; Female; Fluorescent Ant | 1990 |
[Sensitivity and specificity of the determination of urinary catecholamines and their acid metabolites in the diagnosis of neuroblastoma in children].
Topics: Adolescent; Catecholamines; Child; Child, Preschool; Dopamine; Epinephrine; Homovanillic Acid; Human | 1990 |
Urinary vanillylmandelic acid and homovanillic acid levels in randomly-sampled urine for the mass screening of neuroblastoma.
Topics: Homovanillic Acid; Humans; Infant; Mass Screening; Neuroblastoma; Sensitivity and Specificity; Vanil | 1990 |
Problems of mass screening for neuroblastoma: analysis of false-negative cases.
Topics: Adrenal Gland Neoplasms; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chromosomes | 1990 |
Opsoclonus-ataxia due to childhood neural crest tumors: a chronic neurologic syndrome.
Topics: Abdominal Neoplasms; Cerebellar Ataxia; Child, Preschool; Diagnosis, Differential; Eye Movements; Fe | 1990 |
Modification of the indolamine content in neuroblastoma x glioma hybrid NG108-15 cells upon induced differentiation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Biogenic Monoamines; Bucladesine; Cell Differentiation; Dopamine; Gl | 1989 |
Can mass screening for neuroblastoma detect patients with low vanillylmandelic acid and high homovanillic acid?
Topics: Homovanillic Acid; Humans; Mass Screening; Neuroblastoma; Predictive Value of Tests; Vanilmandelic A | 1989 |
Stage and urinary catecholamine metabolite excretion in neuroblastoma. European Neuroblastoma Study Group.
Topics: Age Factors; Child; Europe; Homovanillic Acid; Humans; Infant; Neoplasm Staging; Neuroblastoma; Prog | 1989 |
Cases of neuroblastoma missed by the mass screening programs.
Topics: Child, Preschool; False Negative Reactions; Female; Ganglioneuroma; Homovanillic Acid; Humans; Infan | 1989 |
[Clinical significance of homovanillic acid analysis in endocrine tests of the adrenal medulla and sympathetic nervous system].
Topics: Adrenal Medulla; Alzheimer Disease; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; | 1989 |
A new urinary mass screening system for neuroblastoma in infancy by use of monoclonal antibodies against VMA and HVA.
Topics: Antibodies, Monoclonal; Child; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Immu | 1989 |
Feasibility study for neonatal neuroblastoma screening in the United States.
Topics: Biomarkers, Tumor; Creatinine; Feasibility Studies; Female; Homovanillic Acid; Humans; Infant; Infan | 1989 |
History and current status of neuroblastoma screening in Japan.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Homovanillic Acid; Humans; Infant; | 1989 |
Thin-layer chromatography of urinary homovanillic acid and vanillylmandelic acid for large-scale neuroblastoma mass screening.
Topics: Canada; Chromatography, Thin Layer; False Positive Reactions; Homovanillic Acid; Humans; Indicators | 1989 |
Biochemical screening for neuroblastoma in infants: a feasibility study.
Topics: Chromatography, Gas; England; Homovanillic Acid; Humans; Infant; Mass Screening; Neuroblastoma; Pilo | 1989 |
Japanese experience of screening.
Topics: Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Humans; Infant; Japan; Male; Mass S | 1989 |
Neuroblastoma screening: the Canadian experience.
Topics: Amino Acids; Canada; Chromatography, Thin Layer; False Positive Reactions; Homovanillic Acid; Humans | 1989 |
[Clinical evaluation of I-131 metaiodobenzylguanidine (MIBG) imaging in suspected neuroblastoma].
Topics: 3-Iodobenzylguanidine; Carboxylesterase; Carboxylic Ester Hydrolases; Child; Child, Preschool; Femal | 1989 |
N-myc oncogene amplification and catecholamine metabolism in children with neuroblastoma.
Topics: Catecholamines; Gene Amplification; Homovanillic Acid; Humans; Infant; Neuroblastoma; Oncogenes; Van | 1987 |
Screening for neuroblastoma.
Topics: Homovanillic Acid; Humans; Infant; Neuroblastoma; Prognosis; Vanilmandelic Acid | 1987 |
Screening for neuroblastoma.
Topics: Homovanillic Acid; Humans; Infant; Neuroblastoma; Prognosis; Vanilmandelic Acid | 1987 |
Screening for neuroblastoma.
Topics: Child; Child, Preschool; Homovanillic Acid; Humans; Infant; Infant, Newborn; Japan; Mass Screening; | 1987 |
Laboratory techniques and neuroblastoma screening.
Topics: Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Infant; Japan; Neuroblastoma; Vanil | 1988 |
Excretion of octopamine metabolites in neuroblastoma.
Topics: 2-Hydroxyphenethylamine; Child, Preschool; Female; Homovanillic Acid; Humans; Infant; Infant, Newbor | 1986 |
Biochemical monitoring of children with neuroblastoma.
Topics: Aminoisobutyric Acids; Child; Cystathionine; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Levo | 1986 |
Feasibility of chemical screening of urine for neuroblastoma case finding in infancy in Quebec.
Topics: Attitude to Health; Chromatography, Thin Layer; Cost-Benefit Analysis; Feasibility Studies; Homovani | 1987 |
[Value of the determination of serum catecholamine metabolites in the early diagnosis of neuroblastoma].
Topics: Catecholamines; Child; Homovanillic Acid; Humans; Methoxyhydroxyphenylglycol; Neuroblastoma; Vanilma | 1987 |
Does N-myc amplification correlate with other prognostic factors in advanced neuroblastoma? Preliminary results.
Topics: Biomarkers, Tumor; Ferritins; Gene Amplification; Genes, myc; Homovanillic Acid; Humans; Italy; L-La | 1986 |
Determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid in dried urine on filter-paper discs by high-performance liquid chromatography with coulometric electrochemical detection for neuroblastoma screening.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Female; Filtration; Homovanillic Acid; Human | 1988 |
Method of measurement of urinary homovanillic acid and vanillylmandelic acid by gas chromatography-mass spectrometry suitable for neuroblastoma screening.
Topics: Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Infant; Nervous System Neoplasms; N | 1988 |
Dopaminergic neuroblastoma as a poor prognostic subgroup.
Topics: Adrenal Gland Neoplasms; Child, Preschool; Dopamine; Epinephrine; Female; Homovanillic Acid; Humans; | 1988 |
Conjugated versus "free" acidic metabolites of catecholamines in random urine samples: significance for the diagnosis of neuroblastoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Catecholamines; Child; Child, Preschool; Creatinine; Homovanillic Ac | 1988 |
Elevation of lumbar cerebrospinal fluid catecholamine metabolites in patients with cranial and/or intracranial metastatic neuroblastoma.
Topics: Brain Neoplasms; Catecholamines; Child; Child, Preschool; Homovanillic Acid; Humans; Infant; Neurobl | 1988 |
Determination of serum catecholamine metabolites in neuroblastoma by high performance liquid chromatography with electrochemical detection.
Topics: Biomarkers, Tumor; Child; Child, Preschool; Chromatography, High Pressure Liquid; Electrochemistry; | 1986 |
The value of catecholamine metabolite determination on untimed urine collections in the diagnosis of neural crest tumours in children.
Topics: Child; Child, Preschool; Female; Ganglioneuroma; Homovanillic Acid; Humans; Infant; Infant, Newborn; | 1986 |
Neuroblastoma: the case for screening infants in North America.
Topics: Chromatography, Gas; Feasibility Studies; Homovanillic Acid; Humans; Infant; Infant, Newborn; Japan; | 1987 |
Elevation of cerebrospinal fluid catecholamine metabolites in patients with intracranial tumors of neuroectodermal origin.
Topics: Brain Neoplasms; Eye Neoplasms; Glycols; Homovanillic Acid; Humans; Leukemia; Methoxyhydroxyphenylgl | 1987 |
Seasonal variations in vanillylmandelic acid and homovanillic acid in infants' urine.
Topics: Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Infant; Japan; Mass Screening; Neur | 1987 |
Determination of urinary homovanillic and vanillylmandelic acids from dried filter paper samples: assessment of potential methods for neuroblastoma screening.
Topics: Adolescent; Child; Child, Preschool; Chromatography, Gas; Chromatography, Thin Layer; Costs and Cost | 1987 |
Establishment of cut off values for vanillylmandelic acid and homovanillic acid in 24-hr urine accumulation during mass screening for neuroblastoma.
Topics: Chromatography, High Pressure Liquid; Creatinine; Female; Homovanillic Acid; Humans; Infant; Japan; | 1987 |
Simple liquid-chromatographic measurement of vanillylmandelic acid and homovanillic acid in urine on filter paper for mass screening of neuroblastoma in infants.
Topics: Chromatography, High Pressure Liquid; Creatinine; Female; Homovanillic Acid; Humans; Infant; Male; M | 1987 |
The value of determination of homovanillic and vanillylmandelic acids in plasma for the diagnosis and follow-up of neuroblastoma in children.
Topics: Child; Follow-Up Studies; Homovanillic Acid; Humans; Neoplasm Recurrence, Local; Neuroblastoma; Soft | 1987 |
[Rapid determination of 4-hydroxy-3-methoxymandelic (vanilmandelic) acid and 4-hydroxy-3-methoxyphenylacetic (homovanillic) acid in urine by liquid chromatography with electrochemical detection].
Topics: Child; Child, Preschool; Chromatography, High Pressure Liquid; Electrochemistry; Female; Homovanilli | 1986 |
[Amplification of the N-myc cellular oncogene in neuroblastoma. Relation to other tumor markers].
Topics: Child; Child, Preschool; Female; Ferritins; Gene Amplification; Homovanillic Acid; Humans; Infant; L | 1986 |
Vanillylmandelic acid, homovanillic acid, and catecholamines in urine of infants with neuroblastoma 6- to 11-month-old.
Topics: Catecholamines; Homovanillic Acid; Humans; Infant; Japan; Mass Screening; Neuroblastoma; Reference V | 1986 |
Three years of experience with random urinary homovanillic and vanillylmandelic acid levels in the diagnosis of neuroblastoma.
Topics: Child, Preschool; Chromatography, Gas; False Negative Reactions; Homovanillic Acid; Humans; Infant; | 1987 |
Determination of urinary vanillylmandelic acid and homovanillic acid by high performance liquid chromatography for mass screening of neuroblastoma.
Topics: Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Infant; Mass Screening; Neuroblasto | 1986 |
Value of random urinary homovanillic acid and vanillylmandelic acid levels in the diagnosis and management of patients with neuroblastoma: comparison with 24-hour urine collections.
Topics: Adolescent; Catecholamines; Child; Child, Preschool; Homovanillic Acid; Humans; Infant; Infant, Newb | 1985 |
"Total" acidic metabolites of catecholamines in urine as determined by hydrolysis with hydriodic acid and liquid chromatography: application to patients with neuroblastoma and melanoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acids; Adult; Catecholamines; Child; Child, Preschool; Chromatograph | 1985 |
Assessment of the diurnal variations in urinary homovanillic and vanillylmandelic acid excretion for the diagnosis and follow-up of patients with neuroblastoma.
Topics: Child; Child, Preschool; Circadian Rhythm; Follow-Up Studies; Homovanillic Acid; Humans; Infant; Neu | 1985 |
Liquid chromatographic analysis of 4-hydroxy-3-methoxymandelic acid (VMA) and 4-hydroxy-3-methoxyphenylacetic acid (HVA) in urine.
Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Neuroblast | 1985 |
[Chemotherapy of radically unresectible neuroblastoma in the 1st 18 months of life. Importance of quantitative determination of dopamine, vanilmandelic and homovanillic acids].
Topics: Abdominal Neoplasms; Cyclophosphamide; Dopamine; Drug Therapy, Combination; Female; Homovanillic Aci | 1974 |
Separation and determination of urinary homovanillic acid and iso-homovanillic acid by gas-liquid chromatography and electron capture detection.
Topics: Adolescent; Adult; Child; Chromatography, Gas; Creatine; Dihydroxyphenylalanine; Homovanillic Acid; | 1973 |
Biochemical and histologic determinants in the prognosis of neuroblastoma.
Topics: Adolescent; Age Factors; Catecholamines; Child; Child, Preschool; Computers; Female; Follow-Up Studi | 1973 |
The multiple manifestations of neuroblastoma.
Topics: Abdominal Neoplasms; Age Factors; Bone Neoplasms; Carcinoembryonic Antigen; Child, Preschool; Cyclop | 1973 |
Catecholamine metabolism in the carcinoid syndrome.
Topics: Catecholamines; Creatine; Diagnosis, Differential; Epinephrine; Female; Homovanillic Acid; Humans; H | 1974 |