Page last updated: 2024-08-18

pyrazolanthrone and Neuroblastoma

pyrazolanthrone has been researched along with Neuroblastoma in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (44.44)29.6817
2010's9 (50.00)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Ahn, H; Hah, JM; Jung, K; Kim, M; Kim, MH; Kwon, YH; Lee, J; Park, YJ1
Chandrasekaran, J; Gunasekaran, V; Jayaraman, S; Karuppaiah, A; Nanchappan, V; Pk, N; Rajan, RK1
Jang, DS; Jung, JW; Kim, DH; Kwon, H; Lee, S; Lee, YC; Park, HJ; Ryu, JH1
Kluftinger, A; Little, JP; Mah, D; Simtchouk, S; Wan, Z1
Alfonso, A; Alonso, E; Botana, LM; Ebel, R; Jaspars, M; Leirós, M; Rateb, ME1
Giri, RK; Sidhar, H1
Chang, LS; Chen, KC; Kao, PH; Liu, WH1
Chang, CL; Chang, HH; Hsieh, FJ; Hsu, WM; Hu, MK; Huang, MC; Huang, SF; Jeng, YM; Juan, HF; Lee, H; Liao, YF; Lin, KH; Shih, YY; Tsao, PN; Tsay, YG; Wang, BJ1
Das, HK; Mueller, B; Tchedre, K1
Chen, CH; Chen, KL; Chen, SJ; Huang, CF; Hung, DZ; Jinn, TR; Lee, kI; Su, CC; Su, YC; Tang, FC; Tseng, TJ; Yen, CC1
Berglund, CM; Budd Haeberlein, SL; Persson, MA; Radesäter, AC1
Green, KN; Peers, C; Settle, VJ; Vaughan, PF; Webster, NJ1
Alvarez, S; Fresno, M; Muñoz-Fernández, M; Serramía, MJ1
Dhar, S; Herdman, ML; Huang, Y; Kiningham, KK; Marcelo, A; Niles, RM1
Ciani, L; Salinas, PC1
Wang, SG; Wu, MF1
Chi, CW; Lee, HC; Wang, SF; Yen, JC; Yin, PH1
Das, HK; Lee, S1

Other Studies

18 other study(ies) available for pyrazolanthrone and Neuroblastoma

ArticleYear
Syntheses and biological evaluation of 1-heteroaryl-2-aryl-1H-benzimidazole derivatives as c-Jun N-terminal kinase inhibitors with neuroprotective effects.
    Bioorganic & medicinal chemistry, 2013, Apr-15, Volume: 21, Issue:8

    Topics: Benzimidazoles; Cell Line, Tumor; Humans; Mitogen-Activated Protein Kinase 10; Models, Molecular; Neuroblastoma; Neuroprotective Agents; Phosphorylation; Protein Kinase Inhibitors; Structure-Activity Relationship

2013
C-Glucosyl Xanthone derivative Mangiferin downregulates the JNK3 mediated caspase activation in Almal induced neurotoxicity in differentiated SHSY-5Y neuroblastoma cells.
    Toxicology mechanisms and methods, 2023, Volume: 33, Issue:9

    Topics: Caspases; Humans; Neuroblastoma; Xanthones

2023
Echinocystic Acid Facilitates Neurite Outgrowth in Neuroblastoma Neuro2a Cells and Enhances Spatial Memory in Aged Mice.
    Biological & pharmaceutical bulletin, 2017, Volume: 40, Issue:10

    Topics: Aging; Animals; Anthracenes; Cell Line, Tumor; Hippocampus; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mice; Neuroblastoma; Neuronal Outgrowth; Oleanolic Acid; Phosphorylation; Spatial Learning; Spatial Memory

2017
Human adipose tissue conditioned media from lean subjects is protective against H2O2 induced neurotoxicity in human SH-SY5Y neuronal cells.
    International journal of molecular sciences, 2015, Jan-06, Volume: 16, Issue:1

    Topics: Adipose Tissue; Alzheimer Disease; Anthracenes; Cell Line, Tumor; Cell Survival; Chromones; Culture Media, Conditioned; Flavonoids; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction

2015
The Streptomyces metabolite anhydroexfoliamycin ameliorates hallmarks of Alzheimer's disease in vitro and in vivo.
    Neuroscience, 2015, Oct-01, Volume: 305

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anthracenes; Antipsychotic Agents; Aspartic Acid Endopeptidases; Brain; Cell Line, Tumor; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; MAP Kinase Kinase Kinases; Mice; Mice, Transgenic; Mutation; Neuroblastoma; Peptide Fragments; Presenilin-1; Prodigiosin; tau Proteins

2015
Induction of Bex genes by curcumin is associated with apoptosis and activation of p53 in N2a neuroblastoma cells.
    Scientific reports, 2017, 02-01, Volume: 7

    Topics: Androstadienes; Animals; Anthracenes; Apoptosis; Benzothiazoles; Cell Line, Tumor; Curcumin; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; JNK Mitogen-Activated Protein Kinases; Mice; Models, Biological; Nerve Tissue Proteins; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Signal Transduction; Time Factors; Toluene; Tumor Suppressor Protein p53; Wortmannin

2017
Calcium-stimulated mitogen-activated protein kinase activation elicits Bcl-xL downregulation and Bak upregulation in notexin-treated human neuroblastoma SK-N-SH cells.
    Journal of cellular physiology, 2010, Volume: 222, Issue:1

    Topics: Activating Transcription Factor 2; Anthracenes; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Calcium; Caspase 9; Cell Line, Tumor; Down-Regulation; Egtazic Acid; Elapid Venoms; Enzyme Activation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Reactive Oxygen Species; Signal Transduction; Up-Regulation

2010
Notch1 expression predicts an unfavorable prognosis and serves as a therapeutic target of patients with neuroblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Sep-01, Volume: 16, Issue:17

    Topics: Amyloid Precursor Protein Secretases; Animals; Anthracenes; Blotting, Western; Calreticulin; Cell Differentiation; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Kaplan-Meier Estimate; Mice; Mice, Nude; Microscopy, Confocal; Neuroblastoma; Oligopeptides; Predictive Value of Tests; Prognosis; Receptor, Notch1; RNA Interference; Signal Transduction; Xenograft Model Antitumor Assays

2010
Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
    Journal of neurochemistry, 2012, Volume: 122, Issue:3

    Topics: Amyloid Precursor Protein Secretases; Anthracenes; Calcium; Carrier Proteins; Cell Line, Tumor; Cytosol; DNA Helicases; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Inositol 1,4,5-Trisphosphate Receptors; Methionine; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Mutation; Neuroblastoma; Nuclear Proteins; Peptide Fragments; Presenilin-1; Signal Transduction; Statistics, Nonparametric; Thapsigargin; Transfection; Valine

2012
Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals.
    Toxicology, 2013, Jan-07, Volume: 303

    Topics: Acetates; Animals; Anthracenes; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Glutathione; Imidazoles; Mice; Mitochondria; Neuroblastoma; Neurons; Neurotoxicity Syndromes; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines

2013
UV-induced apoptosis in SH-SY5Y cells: contribution to apoptosis by JNK signaling and cytochrome c.
    Journal of neuroscience research, 2004, Nov-15, Volume: 78, Issue:4

    Topics: Anthracenes; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Mitochondria; Neuroblastoma; Proto-Oncogene Proteins c-jun; Time Factors; Ultraviolet Rays

2004
Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways.
    Brain research. Molecular brain research, 2004, Nov-04, Volume: 130, Issue:1-2

    Topics: ADAM Proteins; ADAM10 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Anthracenes; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression Regulation; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Membrane Proteins; Metalloendopeptidases; Mitogen-Activated Protein Kinase Kinases; Neuroblastoma; Oxazoles; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Stress, Physiological; Time Factors

2004
Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-kappaB and activating protein-1 mediated mechanism.
    Journal of neurochemistry, 2005, Volume: 94, Issue:3

    Topics: Anthracenes; Antioxidants; Blotting, Northern; CD4 Antigens; Cell Line, Tumor; Chemokine CCL5; Chemokine CXCL12; Chemokines, CXC; Cyclooxygenase 2; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression; HIV Envelope Protein gp120; Humans; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Luciferases; Membrane Proteins; Mutagenesis; Neuroblastoma; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proline; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-jun; Pyridines; Receptors, CCR5; Receptors, CXCR4; Thiocarbamates; Time Factors; Transcription Factor AP-1; Transfection; Tumor Necrosis Factor-alpha

2005
Thimerosal induces apoptosis in a neuroblastoma model via the cJun N-terminal kinase pathway.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 92, Issue:1

    Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Enzyme Inhibitors; Humans; JNK Mitogen-Activated Protein Kinases; Neuroblastoma; Phosphorylation; Thimerosal; Transcription Factor AP-1

2006
c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability.
    BMC cell biology, 2007, Jul-03, Volume: 8

    Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; Anisomycin; Anthracenes; Bucladesine; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Cerebellum; Dishevelled Proteins; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; JNK Mitogen-Activated Protein Kinases; Mice; Microtubules; Neuroblastoma; Neurons; Nocodazole; Phosphoproteins; Time Factors; Transfection; Wnt Proteins

2007
Human TAO kinase 1 induces apoptosis in SH-SY5Y cells.
    Cell biology international, 2008, Volume: 32, Issue:1

    Topics: Anthracenes; Apoptosis; Caspase 3; Cell Line, Tumor; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Neuroblastoma; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Transfection

2008
Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells.
    Toxicology, 2008, Apr-18, Volume: 246, Issue:2-3

    Topics: Anthracenes; Antioxidants; Apoptosis; Cell Line, Tumor; Central Nervous System Stimulants; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Methamphetamine; Neuroblastoma; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Vitamin E

2008
Inhibition of basal activity of c-jun-NH2-terminal kinase (JNK) represses the expression of presenilin-1 by a p53-dependent mechanism.
    Brain research, 2008, May-01, Volume: 1207

    Topics: Analysis of Variance; Anthracenes; Cell Line, Tumor; Chromatin Immunoprecipitation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 8; Neuroblastoma; Presenilin-1; RNA, Small Interfering; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation

2008