cycloleucine and Neuroblastoma
cycloleucine has been researched along with Neuroblastoma in 5 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" The cotransporter activity in human neuroblastoma SH-SY5Y cells was assessed by bumetanide-sensitive K+ influx, and protein expression was evaluated by Western blot analysis." | 3.70 | Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate. ( Murali, SG; Sun, D, 1998) |
Research
Studies (5)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Lee, RK | 1 |
Wurtman, RJ | 1 |
Cox, AJ | 1 |
Nitsch, RM | 1 |
Sorrentino, G | 2 |
Singh, IN | 2 |
Massarelli, R | 1 |
Kanfer, JN | 2 |
Sun, D | 1 |
Murali, SG | 1 |
Lakshmanan, M | 1 |
Goncalves, E | 1 |
Lessly, G | 1 |
Foti, D | 1 |
Robbins, J | 1 |
Other Studies
5 other studies available for cycloleucine and Neuroblastoma
Article | Year |
---|---|
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Chelating Agents | 1995 |
Stimulation of phospholipase C activity by norepinephrine, t-ACPD and bombesin in LA-N-2 cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alanine; Bombesin; Cycloleucine; Excitatory A | 1996 |
Amyloid beta protein (25-35) stimulation of phospholipase C in LA-N-2 cells.
Topics: Adrenergic Agonists; Adrenergic alpha-Agonists; Amyloid beta-Peptides; Bombesin; Calcium; Chelating | 1997 |
Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Bumetanide; Carrier Proteins; Cycloleucine | 1998 |
The transport of thyroxine into mouse neuroblastoma cells, NB41A3: the effect of L-system amino acids.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Antimycin A; Binding, Competitive; Biological Transport | 1990 |