trimethyloxamine has been researched along with Neuroblastoma in 2 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, we show that exposure of scrapie-infected mouse neuroblastoma (ScN2a) cells to reagents known to stabilize proteins in their native conformation reduced the rate and extent of PrP(Sc) formation." | 1.29 | Chemical chaperones interfere with the formation of scrapie prion protein. ( Prusiner, SB; Tatzelt, J; Welch, WJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Georgescauld, F | 1 |
| Mocan, I | 1 |
| Lacombe, ML | 1 |
| Lascu, I | 1 |
| Tatzelt, J | 1 |
| Prusiner, SB | 1 |
| Welch, WJ | 1 |
2 other studies available for trimethyloxamine and Neuroblastoma
| Article | Year |
|---|---|
Rescue of the neuroblastoma mutant of the human nucleoside diphosphate kinase A/nm23-H1 by the natural osmolyte trimethylamine-N-oxide.
Topics: Dose-Response Relationship, Drug; Humans; Kinetics; Methylamines; Neoplasm Proteins; Neuroblastoma; | 2009 |
Chemical chaperones interfere with the formation of scrapie prion protein.
Topics: Animals; Brain; Cell Line; Dimethyl Sulfoxide; Glycerol; Kinetics; Methylamines; Mice; Molecular Cha | 1996 |