selegiline has been researched along with Neuroblastoma in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (39.29) | 18.2507 |
| 2000's | 11 (39.29) | 29.6817 |
| 2010's | 5 (17.86) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Ekpo, OE; Enogieru, AB; Joubert, J; Malan, SF; Omoruyi, SI; Zindo, FT | 1 |
| Arawaka, S; Kato, T; Nakamura, Y; Sasaki, A; Sato, H; Shigekiyo, T; Takahata, K; Tsunekawa, H | 1 |
| Mishra, KP; Niranjan, R; Thakur, AK | 1 |
| Maruyama, W; Naoi, M; Osawa, T; Shamoto-Nagai, M; Wu, Y | 1 |
| Johnson, C; Johnson, S; Lu, D; Ou, XM; Stockmeier, CA; Tazik, S; Youdim, MB | 1 |
| Austin, MC; Chen, K; Dieter, L; Johnson, C; Jurjus, GJ; Lu, D; Luo, J; May, W; Meltzer, HY; Ou, XM; Overholser, JC; Sawa, A; Shih, JC; Stockmeier, CA; Youdim, MB | 1 |
| Akao, Y; Inaba-Hasegawa, K; Maruyama, W; Naoi, M | 1 |
| Carlson, EC; Ebadi, M; Sharma, SK | 1 |
| Carlson, EC; Ebadi, M; Shavali, S; Swinscoe, JC | 1 |
| Ramsden, DB; Rieder, CR; Williams, AC | 1 |
| Bellik, L; Marco, JI; Romera, M; Sanz, E; Unzeta, M | 1 |
| Imamura, K; Nakamura, C; Nakashima, K; Nakaso, K; Sato, H; Takeshima, T | 1 |
| Akao, Y; Maruyama, W; Naoi, M; Shamoto-Nagai, M; Yamaoka, Y; Yi, H | 1 |
| Mackowiak, A; Müller, T; Przuntek, H; Rieks, M | 1 |
| Fahn, S; García de Yébenes, J; Mena, MA; Pardo, B | 1 |
| Yu, PH; Zuo, D | 1 |
| Griffiths, HR; Lambert, DG; Lunec, J; Willets, JM | 1 |
| Chen, K; Ekblom, J; Shih, JC; Zhu, QS | 1 |
| Lai, CT; Yu, PH | 1 |
| Dostert, P; Hashizume, Y; Kasamatsu, T; Kohda, K; Maruyama, W; Naoi, M; Takahashi, T | 1 |
| Furst, P; Kragten, E; Lalande, I; Muller, D; Roggo, S; Schindler, P; van Oostrum, J; Waldmeier, P; Zimmermann, K | 1 |
| Maruyama, W; Naoi, M; Takahashi, T | 1 |
| Maruyama, W; Naoi, M | 1 |
| Kolehmainen, P; Salminen, A; Suuronen, T | 1 |
| Billett, EE; De Girolamo, LA; Hargreaves, AJ | 1 |
| Klegeris, A; McGeer, PL | 1 |
| Casarejos, MJ; Fahn, S; García de Yébenes, J; Mena, MA; Pardo, B | 1 |
| Buckman, TD | 1 |
28 other study(ies) available for selegiline and Neuroblastoma
| Article | Year |
|---|---|
Design, synthesis and evaluation of pentacycloundecane and hexacycloundecane propargylamine derivatives as multifunctional neuroprotective agents.
Topics: Cell Line, Tumor; Drug Design; Humans; Monoamine Oxidase; Neuroblastoma; Neuroprotective Agents; Pargyline; Propylamines; Protein Binding; Structure-Activity Relationship | 2019 |
Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion
Topics: alpha-Synuclein; Animals; ATP-Binding Cassette Transporters; Cell Death; Cell Line, Tumor; Corpus Striatum; Culture Media, Conditioned; Dopaminergic Neurons; Gene Knockdown Techniques; Genetic Vectors; Humans; Indans; Injections; Lysosomes; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Mutation, Missense; Neuroblastoma; Parkinsonian Disorders; Protein Aggregation, Pathological; Protein Transport; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Small Interfering; Selegiline; Substantia Nigra | 2021 |
Inhibition of Cyclooxygenase-2 (COX-2) Initiates Autophagy and Potentiates MPTP-Induced Autophagic Cell Death of Human Neuroblastoma Cells, SH-SY5Y: an Inside in the Pathology of Parkinson's Disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Autophagy; Caspase 3; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Lipopolysaccharides; Nerve Tissue Proteins; Neuroblastoma; Parkinson Disease; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Selegiline; Sulfonamides | 2018 |
Rasagiline prevents cyclosporine A-sensitive superoxide flashes induced by PK11195, the initial signal of mitochondrial membrane permeabilization and apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Calcium; Cell Line, Tumor; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indans; Isoquinolines; Mitochondrial Membranes; Neuroblastoma; Neuroprotective Agents; Oxygen; Proto-Oncogene Proteins c-bcl-2; Reaction Time; Selegiline; Signal Transduction; Superoxides | 2016 |
Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Apoptosis; Brain; Cell Line, Tumor; Dexamethasone; Dose-Response Relationship, Drug; Glioblastoma; Humans; In Situ Nick-End Labeling; Indans; Monoamine Oxidase; Neuroblastoma; Neuroprotective Agents; Selegiline; Tetrazolium Salts; Thiazoles | 2009 |
A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage.
Topics: Alcoholism; Analysis of Variance; Animals; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Line, Tumor; Central Nervous System Depressants; Ethanol; Gene Expression Regulation; Glioblastoma; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Peroxide; Immunoprecipitation; In Situ Nick-End Labeling; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroblastoma; Neurons; Prefrontal Cortex; Rats; Rats, Wistar; Repressor Proteins; RNA, Messenger; Selegiline; Transfection | 2010 |
Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase.
Topics: Analysis of Variance; Cell Line, Tumor; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Indans; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroblastoma; Oxazoles; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Selegiline; Transfection; Up-Regulation | 2012 |
Neuroprotective actions of Selegiline in inhibiting 1-methyl, 4-phenyl, pyridinium ion (MPP+)-induced apoptosis in SK-N-SH neurons.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Cell Line, Tumor; Cell Membrane; Cytoprotection; Dose-Response Relationship, Drug; Free Radicals; Genes, Immediate-Early; Humans; Intracellular Membranes; Microscopy, Electron; Mitochondria; Nerve Degeneration; Neurites; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphatidylserines; Selegiline | 2003 |
1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases alpha-synuclein expression and causes nuclear damage in human dopaminergic cells.
Topics: Adenosine Triphosphate; alpha-Synuclein; Antioxidants; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Coenzymes; Cysteine Proteinase Inhibitors; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Glutathione; Humans; Immunohistochemistry; Microscopy, Electron; Nerve Tissue Proteins; Neuroblastoma; Neuroprotective Agents; Oligopeptides; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selegiline; Synucleins; Tetrahydroisoquinolines; Time Factors; Ubiquinone | 2004 |
Selegiline increases heme oxygenase-1 expression and the cytotoxicity produced by dopamine treatment of neuroblastoma SK-N-SH cells.
Topics: Blotting, Northern; Cardiotonic Agents; Dopamine; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Membrane Proteins; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selegiline; Tumor Cells, Cultured | 2004 |
Indolalkylamines derivatives as antioxidant and neuroprotective agents in an experimental model of Parkinson's disease.
Topics: Animals; Antioxidants; Antiparkinson Agents; Brain; Brain Chemistry; Cell Line, Tumor; Dopamine; Dose-Response Relationship, Drug; Humans; Indoles; Melanins; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Selegiline; Tryptamines | 2004 |
Novel cytoprotective mechanism of anti-parkinsonian drug deprenyl: PI3K and Nrf2-derived induction of antioxidative proteins.
Topics: Antioxidants; Antiparkinson Agents; Cell Line, Tumor; Cytoprotection; Dose-Response Relationship, Drug; Humans; Neoplasm Proteins; Neuroblastoma; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Selegiline | 2006 |
Neuroprotection by propargylamines in Parkinson's disease: intracellular mechanism underlying the anti-apoptotic function and search for clinical markers.
Topics: Alkynes; Cell Death; Cell Line, Tumor; Energy Metabolism; Genetic Markers; Glial Cell Line-Derived Neurotrophic Factor; Humans; Indans; Membrane Potentials; Mitochondria; Neuroblastoma; Neuroprotective Agents; NF-kappa B; Oligonucleotide Array Sequence Analysis; Pargyline; Parkinson Disease; Propylamines; Proto-Oncogene Proteins c-bcl-2; Selegiline | 2007 |
Selegiline reduces cisplatin-induced neuronal death in neuroblastoma cells.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cisplatin; Drug Interactions; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neuroblastoma; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Selegiline; Time Factors | 2008 |
Ascorbic acid protects against levodopa-induced neurotoxicity on a catecholamine-rich human neuroblastoma cell line.
Topics: Ascorbic Acid; Brain; Brain Neoplasms; Catecholamines; Cell Line; Drug Interactions; Female; Humans; Levodopa; Male; Neuroblastoma; Parkinson Disease; Quinones; Selegiline | 1993 |
Increase of survival of dopaminergic neuroblastoma in co-cultures with C-6 glioma by R-(-)-deprenyl.
Topics: Brain Neoplasms; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Glioma; Humans; Neuroblastoma; Oxidopamine; Selegiline; Tumor Cells, Cultured | 1995 |
Studies on the neurotoxicity of 6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline (salsolinol) in SH-SY5Y cells.
Topics: Adenylyl Cyclases; Adrenergic Uptake Inhibitors; Catecholamines; Cell Death; Clorgyline; Dose-Response Relationship, Drug; Guanylate Cyclase; Humans; Imipramine; Indoles; Isoquinolines; L-Lactate Dehydrogenase; Monoamine Oxidase Inhibitors; Neuroblastoma; Neurotoxins; Nitroprusside; Receptors, Muscarinic; Selegiline; Tumor Cells, Cultured | 1995 |
Monoamine oxidase gene transcription in human cell lines: treatment with psychoactive drugs and ethanol.
Topics: Alcohol Drinking; Antimanic Agents; Antipsychotic Agents; Astrocytoma; Central Nervous System Depressants; Dose-Response Relationship, Drug; Electrophoresis; Ethanol; Humans; Lithium Chloride; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroblastoma; Promoter Regions, Genetic; Psychotropic Drugs; Raclopride; Salicylamides; Selegiline; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
R(-)-deprenyl potentiates dopamine-induced cytotoxicity toward catecholaminergic neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Dopamine; Drug Synergism; Humans; Levodopa; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Pargyline; Propylamines; Reactive Oxygen Species; Selegiline; Tumor Cells, Cultured | 1997 |
An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Apoptosis; Carcinogens; Catalase; Cycloheximide; DNA Damage; Dopamine; Free Radicals; Humans; Microscopy, Fluorescence; Neuroblastoma; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Parkinson Disease; Protein Synthesis Inhibitors; Salsoline Alkaloids; Selegiline; Semicarbazides; Stereoisomerism; Tetrahydroisoquinolines; Tumor Cells, Cultured | 1997 |
Glyceraldehyde-3-phosphate dehydrogenase, the putative target of the antiapoptotic compounds CGP 3466 and R-(-)-deprenyl.
Topics: Animals; Antiparkinson Agents; Apoptosis; Biosensing Techniques; Brain; Cell Line; Gene Expression Regulation; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Microscopy, Fluorescence; Molecular Structure; Muscles; Neuroblastoma; Neuroprotective Agents; Oligonucleotides, Antisense; Oxepins; Parkinson Disease; Photoaffinity Labels; Propylamines; Protein Binding; Rabbits; Rats; Selegiline | 1998 |
(-)-Deprenyl protects human dopaminergic neuroblastoma SH-SY5Y cells from apoptosis induced by peroxynitrite and nitric oxide.
Topics: Antiparkinson Agents; Apoptosis; DNA Damage; Dopamine; Electrophoresis, Agar Gel; Humans; Molsidomine; Monoamine Oxidase Inhibitors; Neuroblastoma; Nitrates; Nitric Oxide; Oxidants; Pyridines; Selegiline; Tumor Cells, Cultured | 1998 |
Neuroprotection by (-)-deprenyl and related compounds.
Topics: Aging; Amphetamines; Animals; Antioxidants; Apoptosis; Cattle; DNA Damage; DNA, Neoplasm; Indans; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Nitrates; Oxidants; Parkinson Disease; Selegiline; Tumor Cells, Cultured | 1999 |
Protective effect of L-deprenyl against apoptosis induced by okadaic acid in cultured neuronal cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cerebellum; Drug Interactions; Enzyme Inhibitors; Etoposide; Hippocampus; Mice; Neuroblastoma; Neurons; Okadaic Acid; Protective Agents; Rats; Rats, Wistar; Selegiline; Tumor Cells, Cultured | 2000 |
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on differentiating mouse N2a neuroblastoma cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Actins; Animals; Axons; Blotting, Western; Bucladesine; Cell Death; Cell Differentiation; Culture Media, Serum-Free; Mice; Monoamine Oxidase; Neuroblastoma; Neurofilament Proteins; Neurons; Neuroprotective Agents; Phosphorylation; Selegiline; Subcellular Fractions; Tubulin; Tumor Cells, Cultured | 2000 |
R-(-)-Deprenyl inhibits monocytic THP-1 cell neurotoxicity independently of monoamine oxidase inhibition.
Topics: Alzheimer Disease; DNA Primers; Gene Expression Regulation, Enzymologic; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Monocytes; Nerve Degeneration; Neuroblastoma; Neurons; Neurotoxins; Parkinson Disease; RNA, Messenger; Selegiline; Tumor Cells, Cultured | 2000 |
Neurotoxicity of levodopa on catecholamine-rich neurons.
Topics: Catecholamines; Cell Line; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Humans; Levodopa; Neuroblastoma; Neurons; Selegiline | 1992 |
Toxicity of MPTP and structural analogs in clonal cell lines of neuronal origin expressing B type monoamine oxidase activity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Survival; Clone Cells; Clorgyline; Isoenzymes; Kinetics; Monoamine Oxidase; Neuroblastoma; Neurons; Selegiline | 1991 |