hydroxyindoleacetic acid has been researched along with Neuroblastoma in 18 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) are biomarkers for the diagnosis and follow-up of neuroblastoma, whereas urinary 5-hydroxyindoleacetic acid (5-HIAA) is used to assess a carcinoid tumor." | 3.88 | Quantification of vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid in urine using a dilute-and-shoot and ultra-high pressure liquid chromatography tandem mass spectrometry method. ( Centeno, C; Eugster, PJ; Grouzmann, E, 2018) |
| "The urinary excretion of vanillylmandelic acid (VMA), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) can be increased in the presence of neuroblastic and carcinoid tumors." | 3.74 | HPLC-mass spectrometry method for quantitative detection of neuroendocrine tumor markers: vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid. ( Cardelli, P; Lionetto, L; Lostia, AM; Simmaco, M; Stigliano, A, 2008) |
| " Consequently, this reaction has long been used to measure tyrosine in tyrosinosis and tyrosinemia, homovanillic acid in neuroblastoma, and 5-hydroxy-3-indoleacetic acid in the carcinoid tumor." | 3.66 | The chemical basis and specificity of the nitrosonaphthol reaction. ( Knight, JA; Robertson, G; Wu, JT, 1983) |
| "Given that carriers of certain Alzheimer's disease (AD)-related PS-1 variants are predisposed to clinical depression and that depression has been historically associated with the mitochondrial enzyme, monoamine oxidase-A (MAO-A), we investigated cortical MAO-A function in the AD-related PS-1(M146V) knock-in mouse." | 1.38 | Monoamine oxidase-A physically interacts with presenilin-1(M146V) in the mouse cortex. ( Baker, GB; Cao, X; Chlan-Fourney, J; Gabriel, GG; Mousseau, DD; Nazarali, AJ; Pennington, PR; Rui, L; Wei, Z, 2012) |
| "Neuroblastoma is a solid tumor occurring usually in children less than 5 years old." | 1.31 | Simultaneous HPLC of twelve monoamines and metabolites shows neuroblastoma cell line releases HVA and HIAA. ( Chen, HR; Cheng, AT; Hsu, YP; Liu, YL, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Correia, AS | 1 |
| Silva, I | 1 |
| Reguengo, H | 1 |
| Oliveira, JC | 1 |
| Vasques-Nóvoa, F | 1 |
| Cardoso, A | 1 |
| Vale, N | 1 |
| Grouzmann, E | 1 |
| Centeno, C | 1 |
| Eugster, PJ | 1 |
| Tajeddinn, W | 1 |
| Persson, T | 1 |
| Calvo-Garrido, J | 1 |
| Seed Ahmed, M | 1 |
| Maioli, S | 1 |
| Vijayaraghavan, S | 1 |
| Kazokoglu, MS | 1 |
| Parrado-Fernández, C | 1 |
| Yoshitake, T | 1 |
| Kehr, J | 1 |
| Francis, P | 1 |
| Winblad, B | 1 |
| Höglund, K | 1 |
| Cedazo-Minguez, A | 1 |
| Aarsland, D | 1 |
| Lionetto, L | 1 |
| Lostia, AM | 1 |
| Stigliano, A | 1 |
| Cardelli, P | 1 |
| Simmaco, M | 1 |
| Manickum, T | 1 |
| Wei, Z | 1 |
| Gabriel, GG | 1 |
| Rui, L | 1 |
| Cao, X | 1 |
| Pennington, PR | 1 |
| Chlan-Fourney, J | 1 |
| Nazarali, AJ | 1 |
| Baker, GB | 1 |
| Mousseau, DD | 1 |
| BIRKENHAEGER, JC | 1 |
| Lachhein, L | 1 |
| Schütz, J | 1 |
| Knight, JA | 1 |
| Robertson, G | 1 |
| Wu, JT | 1 |
| Stefănescu, AM | 1 |
| Liu, YL | 1 |
| Cheng, AT | 1 |
| Chen, HR | 1 |
| Hsu, YP | 1 |
| Zuddas, A | 1 |
| Mancosu, C | 1 |
| Lilliu, V | 1 |
| Sorrentino, G | 1 |
| di Porzio, U | 1 |
| Cianchetti, C | 1 |
| Ponzoni, M | 1 |
| Casalaro, A | 1 |
| Lanciotti, M | 1 |
| Montaldo, PG | 1 |
| Cornaglia-Ferraris, P | 1 |
| Ghahary, A | 1 |
| Vriend, J | 1 |
| Cheng, KW | 1 |
| Schwartz, MK | 1 |
| Feldman, JM | 1 |
| Butler, SS | 1 |
| Chapman, BA | 1 |
| Bivens, CE | 1 |
| Breebaart, K | 1 |
| Haan, AM | 1 |
| Wadman, SK | 1 |
| Sato, T | 1 |
| Yoshinaga, K | 1 |
1 review available for hydroxyindoleacetic acid and Neuroblastoma
| Article | Year |
|---|---|
Biochemical procedures in different forms of cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acid Phosphatase; Adrenal Gland Neoplasms; Alkaline Phos | 1971 |
17 other studies available for hydroxyindoleacetic acid and Neuroblastoma
| Article | Year |
|---|---|
The Effect of the Stress Induced by Hydrogen Peroxide and Corticosterone on Tryptophan Metabolism, Using Human Neuroblastoma Cell Line (SH-SY5Y).
Topics: 5-Hydroxytryptophan; Corticosterone; Humans; Hydrogen Peroxide; Hydroxyindoleacetic Acid; Neuroblast | 2023 |
Quantification of vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid in urine using a dilute-and-shoot and ultra-high pressure liquid chromatography tandem mass spectrometry method.
Topics: Biomarkers; Calibration; Carcinoid Tumor; Chromatography, High Pressure Liquid; Homovanillic Acid; H | 2018 |
Pharmacological Modulations of the Serotonergic System in a Cell-Model of Familial Alzheimer's Disease.
Topics: Amyloid beta-Protein Precursor; Cell Line, Tumor; Chromatography, Liquid; Electrochemical Techniques | 2016 |
HPLC-mass spectrometry method for quantitative detection of neuroendocrine tumor markers: vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid.
Topics: Biomarkers, Tumor; Calibration; Carcinoid Tumor; Chromatography, High Pressure Liquid; Homovanillic | 2008 |
Simultaneous analysis of neuroendocrine tumor markers by HPLC-electrochemical detection.
Topics: Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Child; Child, Preschool; Chromatography, High Pre | 2009 |
Monoamine oxidase-A physically interacts with presenilin-1(M146V) in the mouse cortex.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Chromatography, | 2012 |
METASTASIZING NEUROBLASTOMA WITH EXCRETION OF 5-HYDROXYINDOLEACETIC ACID, SEROTONIN AND 5-HYDROXYTRYPTOPHAN.
Topics: 5-Hydroxytryptophan; Abdominal Neoplasms; Chromatography; Humans; Hydroxyindoleacetic Acid; Indoleac | 1963 |
[Simple test for pheochromocytoma as well as neuroblastoma and small intestine carcinoids. Analysis of 3-methoxy-4-hydroxymandelic acid, 3-methoxy-4-hydroxyphenylacetic acid and 5-hydroxy-indoleacetic acid in urine by chromatoelectrophoresis].
Topics: Antihypertensive Agents; Carcinoid Tumor; Chromatography; Electrophoresis; Humans; Hydroxyindoleacet | 1967 |
The chemical basis and specificity of the nitrosonaphthol reaction.
Topics: Amino Acid Metabolism, Inborn Errors; Carcinoid Tumor; Chemical Phenomena; Chemistry; Guaiacol; Homo | 1983 |
An improvement of the endocrine diagnosis by high-performance liquid chromatography.
Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Chromatography, High Pressure Liquid; Chromatography | 1993 |
Simultaneous HPLC of twelve monoamines and metabolites shows neuroblastoma cell line releases HVA and HIAA.
Topics: Biogenic Monoamines; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Hydroxyindolea | 2000 |
6R-Tetrahydrobiopterin induces dopamine synthesis in a human neuroblastoma cell line, LA-N-1. A cellular model of DOPA-responsive dystonia.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Biopterins; Dopamine; Dopamine Antagonists; Dys | 2002 |
The combination of gamma-interferon and tumor necrosis factor causes a rapid and extensive differentiation of human neuroblastoma cells.
Topics: Acetylcholinesterase; Antigens, Surface; Cell Differentiation; Cytoskeletal Proteins; Dihydroxypheny | 1992 |
Modification of the indolamine content in neuroblastoma x glioma hybrid NG108-15 cells upon induced differentiation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Biogenic Monoamines; Bucladesine; Cell Differentiation; Dopamine; Gl | 1989 |
Catecholamine metabolism in the carcinoid syndrome.
Topics: Catecholamines; Creatine; Diagnosis, Differential; Epinephrine; Female; Homovanillic Acid; Humans; H | 1974 |
Densitometric determination of catecholamine metabolites and 5-hydroxy-indoleacetic acid after two-dimensional thin-layer chromatography on cellulose.
Topics: Acetates; Adult; Catecholamines; Catechols; Cellulose; Child; Chromatography, Thin Layer; Densitomet | 1972 |
A paper strip test for screening of pheochromocytoma.
Topics: Adult; Carcinoid Tumor; Child; Colorimetry; Epinephrine; Female; Humans; Hydroxyindoleacetic Acid; H | 1967 |