1,2-dioctanoylglycerol has been researched along with Neuroblastoma in 9 studies
1,2-dioctanoylglycerol: functions as bioregulator of protein kinase C in human platelets
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dioctanoylglycerol, a synthetic diacylglycerol, stimulated [14C]choline uptake in cultured human neuroblastoma (LA-N-2) cells." | 7.68 | Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line. ( Nitsch, RM; Richardson, UI; Slack, BE; Wurtman, RJ, 1992) |
| "Protein phosphorylation and subsequent dephosphorylation was studied in digitonin-permeabilized neuroblastoma SH-SY5Y cells by measuring the incorporation of [32P]phosphate into myelin basic protein (MBP)." | 3.68 | An okadaic acid-sensitive protein phosphatase counteracts protein kinase C-induced phosphorylation in SH-SY5Y cells. ( Alling, C; Larsson, C; Simonsson, P, 1993) |
| "The activation of protein kinase C was investigated in digitonin-permeabilized human neuroblastoma SH-SY5Y cells by measuring the phosphorylation of the specific protein kinase C substrate myelin basic protein4-14." | 3.68 | Activation of protein kinase C in permeabilized human neuroblastoma SH-SY5Y cells. ( Larsson, C; Mau, S; Saermark, T; Simonsson, P, 1992) |
| "Dioctanoylglycerol, a synthetic diacylglycerol, stimulated [14C]choline uptake in cultured human neuroblastoma (LA-N-2) cells." | 3.68 | Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line. ( Nitsch, RM; Richardson, UI; Slack, BE; Wurtman, RJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Näsman, J | 1 |
| Bart, G | 1 |
| Larsson, K | 1 |
| Louhivuori, L | 1 |
| Peltonen, H | 1 |
| Akerman, KE | 2 |
| Larsson, C | 2 |
| Alling, C | 1 |
| Simonsson, P | 2 |
| Godoy, CM | 1 |
| Cukierman, S | 1 |
| Saermark, T | 1 |
| Mau, S | 1 |
| Slack, BE | 1 |
| Richardson, UI | 1 |
| Nitsch, RM | 1 |
| Wurtman, RJ | 2 |
| Singh, IN | 1 |
| Sorrentino, G | 1 |
| Massarelli, R | 1 |
| Kanfer, JN | 1 |
| Weeks, BS | 1 |
| DiSalvo, J | 1 |
| Kleinman, HK | 1 |
| Jalava, AM | 1 |
| Heikkilä, JE | 1 |
| Liscovitch, M | 1 |
| Slack, B | 1 |
| Blusztajn, JK | 1 |
9 other studies available for 1,2-dioctanoylglycerol and Neuroblastoma
| Article | Year |
|---|---|
The orexin OX1 receptor regulates Ca2+ entry via diacylglycerol-activated channels in differentiated neuroblastoma cells.
Topics: Animals; Calcium; Calcium Channels; Cell Differentiation; Cell Line; Cell Line, Tumor; Diglycerides; | 2006 |
An okadaic acid-sensitive protein phosphatase counteracts protein kinase C-induced phosphorylation in SH-SY5Y cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Calcium; Cell Membran | 1993 |
Multiple effects of protein kinase C activators on Na+ currents in mouse neuroblastoma cells.
Topics: Animals; Diglycerides; Enzyme Activation; Fatty Acids; Fatty Acids, Unsaturated; Mice; Neuroblastoma | 1994 |
Activation of protein kinase C in permeabilized human neuroblastoma SH-SY5Y cells.
Topics: Acetophenones; Amino Acid Sequence; Arachidonic Acids; Calcium; Cell Membrane; Cell Membrane Permeab | 1992 |
Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line.
Topics: Acetylcholine; Choline; Diglycerides; Humans; Nervous System Neoplasms; Neuroblastoma; Osmolar Conce | 1992 |
Oleoylamine and sphingosine stimulation of phosphatidylserine synthesis by LA-N-2 cells is protein kinase C independent.
Topics: Amines; Choline; Diglycerides; Down-Regulation; Ethanolamines; Humans; Neuroblastoma; Oleic Acids; P | 1992 |
Laminin-mediated process formation in neuronal cells involves protein dephosphorylation.
Topics: Adrenal Gland Neoplasms; Animals; Cell Adhesion; Diglycerides; Ethers, Cyclic; Glioma; Laminin; Neop | 1990 |
Decline in c-myc mRNA expression but not the induction of c-fos mRNA expression is associated with differentiation of SH-SY5Y human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Differentiation; Cell Line; Diglycerides; Gene E | 1988 |
Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Choline; Chromatography, High Pressure Liqui | 1987 |