dipyridamole has been researched along with Neuroblastoma in 8 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Excerpt | Relevance | Reference |
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"Following earlier observations that increasing the polyunsaturated fatty-acid (PUFA) content of N1E-115 neuroblastoma cells elevated basal and adenosine (Ado)-stimulated intracellular cyclic AMP (cAMP) formation, we carried out studies to determine the mechanism(s) by which PUFA exerted their modulatory effects." | 3.68 | Further studies of the mechanism(s) of polyunsaturated-fatty-acid-mediated increases in intracellular cAMP formation in N1E-115 neuroblastoma cells. ( Byczko, Z; Murphy, MG, 1992) |
"5." | 1.32 | Extracellular metabolism of nucleotides in neuroblastoma x glioma NG108-15 cells determined by capillary electrophoresis. ( Kaulich, M; Müller, CE; Qurishi, R, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (25.00) | 18.7374 |
1990's | 2 (25.00) | 18.2507 |
2000's | 4 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Garcia-Gil, M | 1 |
Pesi, R | 1 |
Perna, S | 1 |
Allegrini, S | 1 |
Giannecchini, M | 1 |
Camici, M | 1 |
Tozzi, MG | 1 |
Kaulich, M | 1 |
Qurishi, R | 1 |
Müller, CE | 1 |
Messina, E | 1 |
Lupi, F | 1 |
Barile, L | 1 |
Giacomello, A | 1 |
Billington, RA | 1 |
Bellomo, EA | 1 |
Floriddia, EM | 1 |
Erriquez, J | 1 |
Distasi, C | 1 |
Genazzani, AA | 1 |
Green, RD | 2 |
Stanberry, LR | 1 |
Murphy, MG | 1 |
Byczko, Z | 1 |
Tebbi, CK | 1 |
Chervinsky, D | 1 |
Baker, RM | 1 |
8 other studies available for dipyridamole and Neuroblastoma
Article | Year |
---|---|
5'-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells.
Topics: 5'-Nucleotidase; Acetylcholine; Aminoimidazole Carboxamide; Apoptosis; Brain; Caspase 3; Caspases; C | 2003 |
Extracellular metabolism of nucleotides in neuroblastoma x glioma NG108-15 cells determined by capillary electrophoresis.
Topics: Adenosine; Alkaline Phosphatase; Animals; Chromatography, Micellar Electrokinetic Capillary; Dipyrid | 2003 |
Cyclic nucleotides and neuroblastoma differentiation.
Topics: Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Cyclic GMP; Dipyridamole; Do | 2004 |
A transport mechanism for NAADP in a rat basophilic cell line.
Topics: Animals; Autocrine Communication; Basophils; Biological Transport; Calcium; Calcium Signaling; Cell | 2006 |
Effects of exogenous adenosine deaminase and erythro-9-(2-hydroxy-3-nonyl) adenine on intracellular cyclic AMP levels in C1300 murine neuroblastoma in tissue culture.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cell Line; Culture Techniques; Cyclic AMP; Dipyrid | 1980 |
Elevation of cyclic AMP in C-1300 murine neuroblastoma by adenosine and related compounds and the antagonism of this response by methylxanthines.
Topics: Adenosine; Animals; Cell Line; Cyclic AMP; Dipyridamole; Mice; Neoplasms, Experimental; Neuroblastom | 1977 |
Further studies of the mechanism(s) of polyunsaturated-fatty-acid-mediated increases in intracellular cAMP formation in N1E-115 neuroblastoma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 5'-Nucleotidase; Adenosine; Basal Metabolism; Colfor | 1992 |
Modulation of drug resistance in homoharringtonine-resistant C-1300 neuroblastoma cells with cyclosporine A and dipyridamole.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, | 1991 |