fluphenazine has been researched along with Neuroblastoma in 5 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " screen phenothiazines for cytotoxic activity in glioma, neuroblastoma, and primary mouse brain tissue; and (2)." | 7.72 | Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors. ( Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E, 2004) |
| " screen phenothiazines for cytotoxic activity in glioma, neuroblastoma, and primary mouse brain tissue; and (2)." | 3.72 | Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors. ( Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E, 2004) |
| "The effects of chlorpromazine and related compounds upon soluble and particulate Ins(1,4,5)P3-5-phosphatase were investigated in rat GH3 pituitary and in human IMR-32 neuroblastoma cells." | 3.68 | Inhibition of inositol-1,4,5-trisphosphate-5-phosphatase by chlorpromazine and related compounds. ( Brännström, G; Fowler, CJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gil-Ad, I | 1 |
| Shtaif, B | 1 |
| Levkovitz, Y | 1 |
| Dayag, M | 1 |
| Zeldich, E | 1 |
| Weizman, A | 1 |
| Silver, MA | 1 |
| Yang, ZW | 1 |
| Ganguli, R | 1 |
| Nimgaonkar, VL | 1 |
| Pénit, J | 2 |
| Cantau, B | 2 |
| Huot, J | 2 |
| Jard, S | 2 |
| Fowler, CJ | 1 |
| Brännström, G | 1 |
5 other studies available for fluphenazine and Neuroblastoma
| Article | Year |
|---|---|
Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calmodulin; Caspase 3; Caspases; Cell Di | 2004 |
An inhibitory effect of psychoactive drugs on a human neuroblastoma cell line.
Topics: Antipsychotic Agents; Cell Division; Cell Line; Dose-Response Relationship, Drug; Flupenthixol; Flup | 1994 |
Adenylate cyclase from synchronized neuroblastoma cells: responsiveness to prostaglandin E1, adenosine, and dopamine during the cell cycle.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cell Division; Cell Line; DNA Replication; Dopamine; Enzyme A | 1977 |
[Adenylate cyclase in synchronized neuroblastoma cells: enzyme response during the cell cycle].
Topics: Adenosine; Adenylyl Cyclases; Cell Division; Cell Line; Dopamine; Fluphenazine; Neuroblastoma; Prost | 1976 |
Inhibition of inositol-1,4,5-trisphosphate-5-phosphatase by chlorpromazine and related compounds.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain Neoplasms; Cells, Cultured; Chlorpromazine; Fluphen | 1992 |