quinazolines has been researched along with Neuroblastoma in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 8 (26.67) | 29.6817 |
| 2010's | 19 (63.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kadomatsu, K; Kishida, S; Kiyonari, S; Sakai, R; Tsubota, S; Yamashita, K | 1 |
| Li, C; Wei, G; Yang, C | 1 |
| Boustanipour, E; Ghaffari, SH; Mesbahi, Y; Sadr, Z; Zekri, A | 1 |
| Anderson, J; Barone, G; Blackledge, MD; Carceller, F; Chesler, L; Clarke, M; Jamin, Y; Jerome, NP; Koers, A; Koh, DM; Marshall, LV; McErlean, CM; McHugh, K; Moreno, L; Pearson, ADJ; Poon, E; Robinson, SP; Sebire, N; Vaidya, SJ; Yuan, Y; Zormpas-Petridis, K | 1 |
| Agarwal, S; Aheman, A; Chen, Z; De Las Casas, A; Foster, JH; Hu, Y; Jin, J; Li, H; Lu, J; Shi, Z; Su, J; Vasudevan, SA; Woodfield, SE; Wu, D; Xu, X; Yan, Y; Yang, J; Yu, X; Yu, Y; Zhai, Y; Zhang, H; Zhao, Y | 1 |
| Chlenski, A; Godley, LA; Lu, Z; Raj, JU; Salwen, HR; Tian, Y; Yang, Q | 1 |
| Leung, KN; Liao, X | 1 |
| Akamizu, T; Hattori, Y; Iwakura, H; Kawano, K; Maitani, Y | 1 |
| Ding, X; Duan, W; Jin, X; Sun, Y; Wang, N; Wang, S; Xiang, L; Zhao, Z | 1 |
| Acaz-Fonseca, E; Garcia-Segura, LM; Ghorbanpoor, S; Grassi, D; Ruiz-Palmero, I | 1 |
| Chen, Z; Guan, S; Lu, J; Mao, X; Pang, JC; Tao, L; Vasudevan, SA; Woodfield, SE; Yang, J; Yu, Y; Zhang, F; Zhang, H; Zhao, Y | 1 |
| Appella, E; Arrowsmith, CH; Giannini, G; Gryder, B; Hager, GL; Hu, Y; Jin, J; Khan, J; Lam, N; Liu, Z; Ma, A; Mazur, SJ; Ozbun, L; Souza, BK; Thiele, CJ; Veschi, V; Voss, TC; Yan, C | 1 |
| Adamson, PC; Blaney, SM; Dancey, JE; Gilbertson, RJ; Hamilton, M; Ingle, AM; Jakacki, RI; Krailo, MD; Tersak, J; Voss, SD | 1 |
| Geoerger, B; Gerstenmeyer, A; Lagodny, J; Niemeyer, CM; Odenthal, E; Rössler, J; Vassal, G | 1 |
| Castellano, A; Cialfi, S; De Ioris, MA; De Laurentis, C; De Pasquale, MD; Dominici, C; Donfrancesco, A; Ilari, I; Jenkner, A; McDowell, HP | 1 |
| Fang, W; Heymach, JV; Nilsson, MB; Palla, S; Zage, PE; Zeng, L; Zweidler-McKay, PA | 1 |
| Hughes, DP; Richards, KN; Speleman, F; Trevino, J; Van Roy, N; Zage, PE; Zweidler-McKay, PA | 1 |
| Chiaraluce, R; d'Erme, M; Fontana, M; Mai, A; Masci, A; Mastromarino, P; Mosca, L; Rotili, D; Tempera, I | 1 |
| Bustos, V; Flajolet, M; Greengard, P; Tian, Y | 1 |
| Billups, CA; Gorlick, R; Houghton, PJ; Keir, ST; Kolb, EA; Maris, JM; Morton, CL; Smith, MA; Wu, J | 1 |
| Billups, CA; Davidoff, AM; Furman, WL; Hawkins, D; Houghton, PJ; Kovach, S; McCarville, MB; McGregor, LM; McPherson, V; Onciu, M; Santana, VM; Stewart, CF; Wu, J | 1 |
| Braoudaki, M; Hatziagapiou, K; Karpusas, M; Tzortzatou-Stathopoulou, F | 1 |
| Buck, DC; Macey, TA; Neve, KA; Wang, C; Yang, R | 1 |
| Brodeur, GM; Cnaan, A; Evans, AE; Hishiki, T; Ho, R; Maris, J; Minturn, JE; Wang, Q; Zhao, H | 1 |
| Gotoh, T; Hosoi, H; Iehara, T; Izumi, M; Kikuchi, K; Kuwahara, Y; Otabe, O; Sugimoto, T; Tamura, S; Tsuchiya, K | 1 |
| Castellano, A; De Ioris, MA; De Laurentis, C; Dominici, C; Donfrancesco, A; Garganese, MC; Ilari, I; Jenkner, A; Milano, GM | 1 |
| Beaudry, P; Folkman, J; Heymach, J; Nilsson, M; Poon, D; Prox, D; Rioth, M; Ryan, A; Ryeom, S; Xu, L; Zweidler-Mckay, P | 1 |
| Chao, CC; Hour, MJ; Kuo, SC; Leung, YM; Shieh, J; Wu, BT | 1 |
| Borgström, P; Eksborg, S; Fredriksson, A; Hassan, M; Ingvar, M; Johnström, P; Kogner, P; Stone-Elander, S; Thorell, JO; von Heijne, G | 1 |
| Carlin, SC; Friedkin, M; Rosenberg, RN; VandeVenter, L | 1 |
2 trial(s) available for quinazolines and Neuroblastoma
| Article | Year |
|---|---|
Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bone Neoplasms; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Diarrhea; Drug Eruptions; ErbB Receptors; Erlotinib Hydrochloride; Humans; Maximum Tolerated Dose; Neoplasm Recurrence, Local; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Osteosarcoma; Quinazolines; Rhabdomyosarcoma; Temozolomide | 2008 |
A single-arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high-risk neuroblastoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Child; Child, Preschool; Female; Gefitinib; Homovanillic Acid; Humans; Immunohistochemistry; Infant; Infant, Newborn; Irinotecan; L-Lactate Dehydrogenase; Male; Neoplasm Proteins; Neuroblastoma; Pilot Projects; Quinazolines; Risk Factors; Treatment Outcome; Tumor Burden; Vanilmandelic Acid | 2012 |
28 other study(ies) available for quinazolines and Neuroblastoma
| Article | Year |
|---|---|
Thymidylate synthase inhibitor raltitrexed can induce high levels of DNA damage in MYCN-amplified neuroblastoma cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA Damage; Dose-Response Relationship, Drug; Gene Amplification; Humans; Metabolic Networks and Pathways; N-Myc Proto-Oncogene Protein; Neuroblastoma; Quinazolines; Thiophenes; Thymidylate Synthase | 2020 |
Vandetanib inhibits cisplatin‑resistant neuroblastoma tumor growth and invasion.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Neoplasm Invasiveness; Neuroblastoma; Piperidines; Proto-Oncogene Proteins c-ret; Quinazolines; Receptors, CXCR4; Signal Transduction | 2018 |
The Potential Contribution of microRNAs in Anti-cancer Effects of Aurora Kinase Inhibitor (AZD1152-HQPA).
Topics: Aurora Kinases; Cell Line, Tumor; Humans; MicroRNAs; Neuroblastoma; Protein Kinase Inhibitors; Quinazolines | 2018 |
MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment.
Topics: Angiogenesis Inhibitors; Animals; Child; Child, Preschool; Contrast Media; Female; Humans; Infant; Magnetic Resonance Imaging; Male; Mice, Transgenic; N-Myc Proto-Oncogene Protein; Neoplasms, Experimental; Neuroblastoma; Prospective Studies; Protein Kinase Inhibitors; Quinazolines; Treatment Outcome | 2019 |
Small molecule inhibitor agerafenib effectively suppresses neuroblastoma tumor growth in mouse models via inhibiting ERK MAPK signaling.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Mice, Nude; Mice, Transgenic; N-Myc Proto-Oncogene Protein; Neuroblastoma; Phenylurea Compounds; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells.
Topics: Apoptosis; Azepines; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D1; DNA Methylation; Doxorubicin; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Quinazolines | 2013 |
Tryptanthrin induces growth inhibition and neuronal differentiation in the human neuroblastoma LA-N-1 cells.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Down-Regulation; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Neuroblastoma; Neurons; Proto-Oncogene Proteins c-myc; Quinazolines; Resting Phase, Cell Cycle | 2013 |
Combination therapy with gefitinib and doxorubicin inhibits tumor growth in transgenic mice with adrenal neuroblastoma.
Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Gefitinib; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroblastoma; Polyethylene Glycols; Quinazolines; Transcriptome | 2013 |
Vandetanib-induced inhibition of neuroblastoma cell migration and invasion is associated with downregulation of the SDF-1/CXCR4 axis and matrix metalloproteinase 14.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Down-Regulation; Drug Screening Assays, Antitumor; G1 Phase Cell Cycle Checkpoints; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 14; Neoplasm Invasiveness; Neuroblastoma; Phosphorylation; Piperidines; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-ret; Quinazolines; Receptors, CXCR4 | 2014 |
The Selective Estrogen Receptor Modulator Raloxifene Regulates Arginine-Vasopressin Gene Expression in Human Female Neuroblastoma Cells Through G Protein-Coupled Estrogen Receptor and ERK Signaling.
Topics: Arginine Vasopressin; Blotting, Western; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Neuroblastoma; Phosphorylation; Protein Kinase C; Pyrroles; Quinazolines; Raloxifene Hydrochloride; Receptors, Estrogen; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Selective Estrogen Receptor Modulators | 2015 |
Novel multi-targeted ErbB family inhibitor afatinib blocks EGF-induced signaling and induces apoptosis in neuroblastoma.
Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Doxorubicin; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Mice; Mice, Nude; Neuroblastoma; Quinazolines; Radiation-Sensitizing Agents; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.
Topics: Cell Differentiation; Cell Proliferation; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Humans; Neuroblastoma; Quinazolines; RNA, Small Interfering; Tumor Suppressor Protein p53 | 2017 |
EGFR inhibition using gefitinib is not active in neuroblastoma cell lines.
Topics: Antineoplastic Agents; Blotting, Western; Cell Proliferation; ErbB Receptors; Flow Cytometry; Gefitinib; Humans; Mutation; Neuroblastoma; Protein Kinase Inhibitors; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Topotecan; Tumor Cells, Cultured | 2009 |
Gefitinib in combination with oral topotecan and cyclophosphamide in relapsed neuroblastoma: pharmacological rationale and clinical response.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neuroblastoma; Pilot Projects; Prognosis; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salvage Therapy; Survival Rate; Topotecan; Treatment Outcome | 2010 |
A novel therapeutic combination for neuroblastoma: the vascular endothelial growth factor receptor/epidermal growth factor receptor/rearranged during transfection inhibitor vandetanib with 13-cis-retinoic acid.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA-Binding Proteins; ErbB Receptors; Humans; Isotretinoin; Mice; Neovascularization, Pathologic; Neuroblastoma; Phosphorylation; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2010 |
Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Humans; Mice; Mice, Knockout; Morpholines; Neoplasm Transplantation; Neuroblastoma; Protein Kinase Inhibitors; Quinazolines; Signal Transduction | 2010 |
Biological effects of MC2050, a quinazoline-based PARP-1 inhibitor, in human neuroblastoma and EBV-positive Burkitt's lymphoma cells.
Topics: Burkitt Lymphoma; Dose-Response Relationship, Drug; Enzyme Inhibitors; Herpesvirus 4, Human; Humans; Neuroblastoma; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Tumor Cells, Cultured | 2011 |
A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.
Topics: Allyl Compounds; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Autophagy; Autophagy-Related Protein 5; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neuroblastoma; Neurons; Peptide Fragments; Quinazolines; Rats | 2011 |
Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program.
Topics: Adolescent; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Glioblastoma; Humans; Infant; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, SCID; Neoplasm Transplantation; Neuroblastoma; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Sarcoma; Sirolimus; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2012 |
Evaluation of antitumor activity of gefitinib in pediatric glioblastoma and neuroblastoma cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gefitinib; Glioblastoma; Humans; Neuroblastoma; Phosphorylation; Quinazolines; Receptor, ErbB-2 | 2011 |
Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases.
Topics: Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Genetic Vectors; Humans; Indole Alkaloids; Microscopy, Confocal; Neuroblastoma; Piperazines; Platelet-Derived Growth Factor; Quinazolines; Quinpirole; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Dopamine D2; Simplexvirus; Spiperone; Transcriptional Activation; Transfection; Tritium; Tyrphostins | 2005 |
Proliferation of human neuroblastomas mediated by the epidermal growth factor receptor.
Topics: Cell Growth Processes; Cell Line, Tumor; ErbB Receptors; Gefitinib; Humans; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines | 2005 |
Induction of apoptosis by an inhibitor of EGFR in neuroblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Gefitinib; Humans; Neuroblastoma; Phosphorylation; Quinazolines | 2007 |
Prolonged response to oral gefitinib, cyclophosphamide, and topotecan in heavily pretreated relapsed stage 4 neuroblastoma: a case report.
Topics: Administration, Oral; Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cyclophosphamide; Female; Gefitinib; Humans; Neuroblastoma; Quinazolines; Radionuclide Imaging; Recurrence; Topotecan; Treatment Outcome | 2007 |
Potent antitumor effects of ZD6474 on neuroblastoma via dual targeting of tumor cells and tumor endothelium.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Drug Delivery Systems; Endothelium; ErbB Receptors; Humans; Male; Mice; Mice, Nude; Neuroblastoma; Phosphorylation; Piperidines; Proto-Oncogene Proteins c-ret; Quinazolines; Tumor Cells, Cultured; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2008 |
HMJ-53A accelerates slow inactivation gating of voltage-gated K+ channels in mouse neuroblastoma N2A cells.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Ion Channel Gating; Membrane Potentials; Mice; Neuroblastoma; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinazolines | 2008 |
In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants.
Topics: Animals; Carbon Radioisotopes; ErbB Receptors; Evaluation Studies as Topic; Female; Humans; Neoplasm Transplantation; Neuroblastoma; Quinazolines; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed; Tumor Cells, Cultured | 1999 |
Quinazoline antifolates as inhibitors of growth, dihydrofolate reductase, and thymidylate synthetase of mouse neuroblastoma cells in culture.
Topics: Animals; Cells, Cultured; Chromatography, Paper; Folic Acid Antagonists; Growth; Kinetics; Leucovorin; Methyltransferases; Mice; Neoplasms, Experimental; Neuroblastoma; Quinazolines; Thymidine; Thymidylate Synthase | 1974 |