Page last updated: 2024-11-05

trientine and Neuroblastoma

trientine has been researched along with Neuroblastoma in 2 studies

Trientine: An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.
TETA : An azamacrocyle in which four nitrogen atoms at positions 1, 4, 8 and 11 of a fouteen-membered ring are each substituted with a carboxymethyl group.
2,2,2-tetramine : A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, MF2
Ciriolo, MR2
Rotilio, G2
Rossi, L2
Marchese, E1

Other Studies

2 other studies available for trientine and Neuroblastoma

ArticleYear
Prolonged copper depletion induces expression of antioxidants and triggers apoptosis in SH-SY5Y neuroblastoma cells.
    Cellular and molecular life sciences : CMLS, 2003, Volume: 60, Issue:8

    Topics: Antioxidants; Apoptosis; Caspases; Chelating Agents; Copper; Electron Transport Complex IV; Humans;

2003
Increased susceptibility of copper-deficient neuroblastoma cells to oxidative stress-mediated apoptosis.
    Free radical biology & medicine, 2001, May-15, Volume: 30, Issue:10

    Topics: Apoptosis; Blotting, Western; Caspase 3; Caspases; Chelating Agents; Copper; Electron Transport Comp

2001