indirubin-3'-monoxime has been researched along with Neuroblastoma in 3 studies
indirubin-3'-monoxime: has antiangiogenic activity
indirubin-3'-monoxime : A member of the class of biindoles that is indirubin in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This paper reports the synthesis of methoxy- and bromo-indirubins, and their antiproliferative activities in human neuroblastoma." | 7.77 | Synthesis of methoxy- and bromo-substituted indirubins and their activities on apoptosis induction in human neuroblastoma cells. ( Hanada, S; Kanda, Y; Miyairi, S; Saito, H; Suzuki, T; Tabata, K, 2011) |
| "This paper reports the synthesis of methoxy- and bromo-indirubins, and their antiproliferative activities in human neuroblastoma." | 3.77 | Synthesis of methoxy- and bromo-substituted indirubins and their activities on apoptosis induction in human neuroblastoma cells. ( Hanada, S; Kanda, Y; Miyairi, S; Saito, H; Suzuki, T; Tabata, K, 2011) |
| "Neuroblastoma is the most common extracranial solid tumor found in infancy and childhood." | 1.39 | Indirubin-3'-oxime induces mitochondrial dysfunction and triggers growth inhibition and cell cycle arrest in human neuroblastoma cells. ( Leung, KN; Liao, XM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saito, H | 1 |
| Tabata, K | 1 |
| Hanada, S | 1 |
| Kanda, Y | 1 |
| Suzuki, T | 1 |
| Miyairi, S | 1 |
| Zhang, S | 1 |
| Zhang, Y | 1 |
| Xu, L | 1 |
| Lin, X | 1 |
| Lu, J | 1 |
| Di, Q | 1 |
| Shi, J | 1 |
| Xu, J | 1 |
| Liao, XM | 1 |
| Leung, KN | 1 |
3 other studies available for indirubin-3'-monoxime and Neuroblastoma
| Article | Year |
|---|---|
Synthesis of methoxy- and bromo-substituted indirubins and their activities on apoptosis induction in human neuroblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; | 2011 |
Indirubin-3'-monoxime inhibits beta-amyloid-induced neurotoxicity in neuroblastoma SH-SY5Y cells.
Topics: Amyloid beta-Peptides; Annexins; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relations | 2009 |
Indirubin-3'-oxime induces mitochondrial dysfunction and triggers growth inhibition and cell cycle arrest in human neuroblastoma cells.
Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Cell Cycle; Cell Proliferation; Colony-Forming Unit | 2013 |