dehydroepiandrosterone has been researched along with Neuroblastoma in 9 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study we investigated the effects of sigma receptor ligands and neurosteroids on bradykinin-induced intracellular calcium concentration ([Ca2+]i) changes in SH-SY5Y neuroblastoma cells." | 3.72 | Modulation of bradykinin-induced calcium changes in SH-SY5Y cells by neurosteroids and sigma receptor ligands via a shared mechanism. ( Hong, W; Nuwayhid, SJ; Werling, LL, 2004) |
| " In a human neuroblastoma cell line, DHEA (1 nM-1 microM) decreased 3H-thymidine uptake (30-60%) and cell viability (23-52%) after 24 hours." | 3.71 | Effect of dehydroepiandrosterone and its sulfate metabolite on neuronal cell viability in culture. ( Eshet, R; Gil-ad, I; Maayan, R; Rehavi, M; Shtaif, B; Weizman, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Hull, B | 1 |
| Wędrychowicz, A | 1 |
| Ossowska, M | 1 |
| Furtak, A | 1 |
| Skoczeń, S | 1 |
| B Starzyk, J | 1 |
| Wu, Z | 1 |
| Li, L | 1 |
| Zheng, LT | 1 |
| Xu, Z | 1 |
| Guo, L | 1 |
| Zhen, X | 1 |
| Lemcke, S | 1 |
| Hönnscheidt, C | 1 |
| Waschatko, G | 1 |
| Bopp, A | 1 |
| Lütjohann, D | 1 |
| Bertram, N | 1 |
| Gehrig-Burger, K | 1 |
| Silvagno, F | 1 |
| Guarnieri, V | 1 |
| Capizzi, A | 1 |
| Pescarmona, GP | 1 |
| Hong, W | 1 |
| Nuwayhid, SJ | 1 |
| Werling, LL | 1 |
| Gao, J | 1 |
| Sun, HY | 1 |
| Zhu, ZR | 1 |
| Ding, Z | 1 |
| Zhu, L | 1 |
| Leskiewicz, M | 1 |
| Regulska, M | 1 |
| Budziszewska, B | 1 |
| Jantas, D | 1 |
| Jaworska-Feil, L | 1 |
| Basta-Kaim, A | 1 |
| Kubera, M | 1 |
| Jagla, G | 1 |
| Nowak, W | 1 |
| Lason, W | 1 |
| Schneider, N | 1 |
| Lanz, S | 1 |
| Ramer, R | 1 |
| Schaefer, D | 1 |
| Goppelt-Struebe, M | 1 |
| Gil-ad, I | 1 |
| Shtaif, B | 1 |
| Eshet, R | 1 |
| Maayan, R | 1 |
| Rehavi, M | 1 |
| Weizman, A | 1 |
9 other studies available for dehydroepiandrosterone and Neuroblastoma
| Article | Year |
|---|---|
Assessment of adrenal function in pediatric cancer survivors.
Topics: Adolescent; Adrenal Insufficiency; Adrenocorticotropic Hormone; Cancer Survivors; Child; Child, Pres | 2022 |
Allosteric modulation of sigma-1 receptors by SKF83959 inhibits microglia-mediated inflammation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Allosteric Regulation; Animals; Anti-Inf | 2015 |
DHEA-Bodipy--a functional fluorescent DHEA analog for live cell imaging.
Topics: Animals; Apoptosis; Biological Transport; Boron Compounds; Cell Membrane; Dehydroepiandrosterone; Es | 2010 |
Synergistic effect of retinoic acid and dehydroepiandrosterone on differentiation of human neuroblastoma cells.
Topics: Cell Differentiation; Cell Division; Cell Movement; Dehydroepiandrosterone; Drug Synergism; Humans; | 2002 |
Modulation of bradykinin-induced calcium changes in SH-SY5Y cells by neurosteroids and sigma receptor ligands via a shared mechanism.
Topics: Binding Sites; Bradykinin; Calcium; Calcium Signaling; Cell Line, Tumor; Dehydroepiandrosterone; Dop | 2004 |
Antioxidant effects of dehydroepiandrosterone are related to up-regulation of thioredoxin in SH-SY5Y cells.
Topics: Antioxidants; Cell Line, Tumor; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Humans; Hy | 2005 |
Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells.
Topics: Apoptosis; Brain; Cell Line, Tumor; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme I | 2008 |
Up-regulation of cyclooxygenase-1 in neuroblastoma cell lines by retinoic acid and corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Benzimidazoles; Bucladesine; Calcimycin; Cell Differe | 2001 |
Effect of dehydroepiandrosterone and its sulfate metabolite on neuronal cell viability in culture.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Cell Survival; Cells, Cultured; Dehydroepiandrosterone; | 2001 |