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methoxsalen and Neuroblastoma

methoxsalen has been researched along with Neuroblastoma in 3 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" However, the poor water solubility, low stability and limited bioavailability have prevented the use of BEO in cancer therapy."1.39Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells. ( Britti, D; Carafa, M; Celia, C; Di Marzio, L; Locatelli, M; Morittu, VM; Navarra, M; Paolino, D; Trapasso, E; Ventura, CA; Wolfram, J, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartnik, M1
Sławińska-Brych, A1
Żurek, A1
Kandefer-Szerszeń, M1
Zdzisińska, B1
Celia, C1
Trapasso, E1
Locatelli, M1
Navarra, M1
Ventura, CA1
Wolfram, J1
Carafa, M1
Morittu, VM1
Britti, D1
Di Marzio, L1
Paolino, D1
Jin, DQ1
Jung, JW1
Lee, YS1
Kim, JA1

Other Studies

3 other studies available for methoxsalen and Neuroblastoma

ArticleYear
8-methoxypsoralen reduces AKT phosphorylation, induces intrinsic and extrinsic apoptotic pathways, and suppresses cell growth of SK-N-AS neuroblastoma and SW620 metastatic colon cancer cells.
    Journal of ethnopharmacology, 2017, Jul-31, Volume: 207

    Topics: Ammi; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Chromatography,

2017
Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells.
    Colloids and surfaces. B, Biointerfaces, 2013, Dec-01, Volume: 112

    Topics: 5-Methoxypsoralen; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Citrus; Drug

2013
2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits cell proliferation through arylhydrocarbon receptor-mediated G1 arrest in SK-N-SH human neuronal cells.
    Neuroscience letters, 2004, Jun-03, Volume: 363, Issue:1

    Topics: Adenovirus E1A Proteins; Benzoflavones; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Ce

2004
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