methoxsalen and Neuroblastoma
methoxsalen has been researched along with Neuroblastoma in 3 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" However, the poor water solubility, low stability and limited bioavailability have prevented the use of BEO in cancer therapy." | 1.39 | Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells. ( Britti, D; Carafa, M; Celia, C; Di Marzio, L; Locatelli, M; Morittu, VM; Navarra, M; Paolino, D; Trapasso, E; Ventura, CA; Wolfram, J, 2013) |
Research
Studies (3)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Bartnik, M | 1 |
Sławińska-Brych, A | 1 |
Żurek, A | 1 |
Kandefer-Szerszeń, M | 1 |
Zdzisińska, B | 1 |
Celia, C | 1 |
Trapasso, E | 1 |
Locatelli, M | 1 |
Navarra, M | 1 |
Ventura, CA | 1 |
Wolfram, J | 1 |
Carafa, M | 1 |
Morittu, VM | 1 |
Britti, D | 1 |
Di Marzio, L | 1 |
Paolino, D | 1 |
Jin, DQ | 1 |
Jung, JW | 1 |
Lee, YS | 1 |
Kim, JA | 1 |
Other Studies
3 other studies available for methoxsalen and Neuroblastoma
Article | Year |
---|---|
8-methoxypsoralen reduces AKT phosphorylation, induces intrinsic and extrinsic apoptotic pathways, and suppresses cell growth of SK-N-AS neuroblastoma and SW620 metastatic colon cancer cells.
Topics: Ammi; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Chromatography, | 2017 |
Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells.
Topics: 5-Methoxypsoralen; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Citrus; Drug | 2013 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits cell proliferation through arylhydrocarbon receptor-mediated G1 arrest in SK-N-SH human neuronal cells.
Topics: Adenovirus E1A Proteins; Benzoflavones; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Ce | 2004 |