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pyridoxal phosphate and Neuroblastoma

pyridoxal phosphate has been researched along with Neuroblastoma in 4 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Phospholipid metabolism in neuroblastoma cells in monolayer culture after acute exposure to pyridoxal phosphate (PLP) has been studied."7.67Effect of pyridoxal 5'-phosphate and valproic acid on phospholipid synthesis in neuroblastoma NA. ( Arienti, G; Binaglia, L; Bocchini, V; Corazzi, L; Freysz, L; Porcellati, F; Roberti, R; Vecchini, A, 1989)
"Phospholipid metabolism in neuroblastoma cells in monolayer culture after acute exposure to pyridoxal phosphate (PLP) has been studied."3.67Effect of pyridoxal 5'-phosphate and valproic acid on phospholipid synthesis in neuroblastoma NA. ( Arienti, G; Binaglia, L; Bocchini, V; Corazzi, L; Freysz, L; Porcellati, F; Roberti, R; Vecchini, A, 1989)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, X1
Hashimoto-Torii, K1
Torii, M1
Ding, C1
Rakic, P1
Lakshmi, S1
Joshi, PG1
Shin, YS1
Rasshofer, R1
Friedrich, B1
Endres, W1
Roberti, R1
Bocchini, V1
Freysz, L1
Vecchini, A1
Corazzi, L1
Arienti, G1
Porcellati, F1
Binaglia, L1

Other Studies

4 other studies available for pyridoxal phosphate and Neuroblastoma

ArticleYear
Gap junctions/hemichannels modulate interkinetic nuclear migration in the forebrain precursors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Mar-24, Volume: 30, Issue:12

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Boron Compounds;

2010
Activation of Src/kinase/phospholipase C/mitogen-activated protein kinase and induction of neurite expression by ATP, independent of nerve growth factor.
    Neuroscience, 2006, Aug-11, Volume: 141, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Butadienes; Cell Line, Tumor; Drug Interactions; Enzyme

2006
Pyridoxal-5'-phosphate determination by a sensitive micromethod in human blood, urine and tissues; its relation to cystathioninuria in neuroblastoma and biliary atresia.
    Clinica chimica acta; international journal of clinical chemistry, 1983, Jan-07, Volume: 127, Issue:1

    Topics: Adolescent; Adult; Bile Ducts; Brain Chemistry; Child; Child, Preschool; Cystathionine; Female; Fetu

1983
Effect of pyridoxal 5'-phosphate and valproic acid on phospholipid synthesis in neuroblastoma NA.
    Biochemical pharmacology, 1989, Oct-15, Volume: 38, Issue:20

    Topics: Energy Metabolism; Lipid Bilayers; Neuroblastoma; Permeability; Phospholipids; Pyridoxal Phosphate;

1989