urea has been researched along with Neuroblastoma in 14 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proteasome inhibitors belong to an important class of anticancer agents and bortezomib (Velcade(®)) has been Food and Drug Administration-approved for the treatment of multiple myeloma (MM) and mantle cell lymphoma." | 7.78 | Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma. ( Bachmann, AS; Ibarra-Rivera, TR; Opoku-Ansah, J; Pirrung, MC, 2012) |
| "The impact of innovative technologies on the target discovery has been employed here to characterize the interactome of STIRUR 41, a promising 3-fluoro-phenyl-5-pyrazolyl-urea derivative endowed with anti-cancer activity, on neuroblastoma-related cells." | 4.31 | Targeting USP-7 by a Novel Fluorinated 5-Pyrazolyl-Urea Derivative. ( Belvedere, R; Brullo, C; Monti, MC; Morretta, E; Petrella, A; Spallarossa, A, 2023) |
| "Proteasome inhibitors belong to an important class of anticancer agents and bortezomib (Velcade(®)) has been Food and Drug Administration-approved for the treatment of multiple myeloma (MM) and mantle cell lymphoma." | 3.78 | Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma. ( Bachmann, AS; Ibarra-Rivera, TR; Opoku-Ansah, J; Pirrung, MC, 2012) |
| "Neuroblastoma is a common neuroendocrine (NE) tumor that presents in early childhood, with a high incidence of malignancy and recurrence." | 1.40 | Specific glycogen synthase kinase-3 inhibition reduces neuroendocrine markers and suppresses neuroblastoma cell growth. ( Carter, YM; Chen, H; Gamblin, TC; Kunnimalaiyaan, M; Kunnimalaiyaan, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Morretta, E | 1 |
| Brullo, C | 1 |
| Belvedere, R | 1 |
| Petrella, A | 1 |
| Spallarossa, A | 1 |
| Monti, MC | 1 |
| Gibadullina, E | 1 |
| Neganova, M | 1 |
| Aleksandrova, Y | 1 |
| Nguyen, HBT | 1 |
| Voloshina, A | 1 |
| Khrizanforov, M | 1 |
| Nguyen, TT | 1 |
| Vinyukova, E | 1 |
| Volcho, K | 1 |
| Tsypyshev, D | 1 |
| Lyubina, A | 1 |
| Amerhanova, S | 1 |
| Strelnik, A | 1 |
| Voronina, J | 1 |
| Islamov, D | 1 |
| Zhapparbergenov, R | 1 |
| Appazov, N | 1 |
| Chabuka, B | 1 |
| Christopher, K | 1 |
| Burilov, A | 1 |
| Salakhutdinov, N | 1 |
| Sinyashin, O | 1 |
| Alabugin, I | 1 |
| Carter, YM | 1 |
| Kunnimalaiyaan, S | 1 |
| Chen, H | 1 |
| Gamblin, TC | 1 |
| Kunnimalaiyaan, M | 1 |
| Dent, P | 1 |
| Georgescauld, F | 1 |
| Mocan, I | 1 |
| Lacombe, ML | 2 |
| Lascu, I | 2 |
| Xu, H | 1 |
| Cheung, IY | 1 |
| Wei, XX | 1 |
| Tran, H | 1 |
| Gao, X | 1 |
| Cheung, NK | 1 |
| Opoku-Ansah, J | 1 |
| Ibarra-Rivera, TR | 1 |
| Pirrung, MC | 1 |
| Bachmann, AS | 1 |
| ORIGENES, ML | 1 |
| BEATTY, EC | 1 |
| BRUBAKER, C | 1 |
| HAMMOND, D | 1 |
| HARTMANN, JR | 1 |
| SHORE, N | 1 |
| WILLIAMS, KO | 1 |
| FERNBACH, DJ | 1 |
| BLOEDOW, CE | 1 |
| Renneboog, B | 1 |
| Decaux, G | 1 |
| Maddock, AL | 1 |
| Westenfelder, C | 1 |
| Erent, M | 1 |
| Gonin, P | 1 |
| Cherfils, J | 1 |
| Tissier, P | 1 |
| Raschellà, G | 1 |
| Giartosio, A | 1 |
| Agou, F | 1 |
| Sarger, C | 1 |
| Konrad, M | 1 |
| Huang, LY | 1 |
| Catterall, WA | 1 |
| Ehrenstein, G | 1 |
14 other studies available for urea and Neuroblastoma
| Article | Year |
|---|---|
Targeting USP-7 by a Novel Fluorinated 5-Pyrazolyl-Urea Derivative.
Topics: Humans; Immunoblotting; Molecular Docking Simulation; Neuroblastoma; Proteomics; Urea | 2023 |
Hybrids of Sterically Hindered Phenols and Diaryl Ureas: Synthesis, Switch from Antioxidant Activity to ROS Generation and Induction of Apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Humans; Molecular Docking Simulation; Neuroblastoma; Phenol; Pheno | 2023 |
Specific glycogen synthase kinase-3 inhibition reduces neuroendocrine markers and suppresses neuroblastoma cell growth.
Topics: Antineoplastic Agents; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Biomarkers, Tumor; B | 2014 |
New methods to control neuroblastoma growth.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Bone Marrow Neoplasms; Cell Proliferation; Glycogen Syntha | 2014 |
Rescue of the neuroblastoma mutant of the human nucleoside diphosphate kinase A/nm23-H1 by the natural osmolyte trimethylamine-N-oxide.
Topics: Dose-Response Relationship, Drug; Humans; Kinetics; Methylamines; Neoplasm Proteins; Neuroblastoma; | 2009 |
Checkpoint kinase inhibitor synergizes with DNA-damaging agents in G1 checkpoint-defective neuroblastoma.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2 | 2011 |
Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Cell Surviva | 2012 |
TRIAL OF HYDROXYUREA (NSC-32065) IN CANCER IN CHILDREN.
Topics: Antineoplastic Agents; Busulfan; Child; Cyclophosphamide; Dactinomycin; Humans; Hydroxyurea; Leukemi | 1964 |
PEDIATRIC CLINICAL TRIALS WITH HYDROXYUREA (NSC-32065).
Topics: Adolescent; Antineoplastic Agents; Child; Drug Therapy; Hodgkin Disease; Hydroxyurea; Leukemia; Neop | 1964 |
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: MISCELLANEOUS TUMORS.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Carcinom | 1964 |
Idiopathic hyponatremia in a young patient: look at the sinus.
Topics: Adult; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Neuroblastoma; Radiography; Urea | 2008 |
Urea induces the heat shock response in human neuroblastoma cells.
Topics: Blotting, Western; Creatinine; Dose-Response Relationship, Drug; Glycerol; Heat-Shock Proteins; Heat | 1996 |
Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene.
Topics: Amino Acid Sequence; Blotting, Western; Catalysis; Enzyme Stability; Hot Temperature; Humans; Isoenz | 2001 |
Comparison of ionic selectivity of batrachotoxin-activated channels with different tetrodotoxin dissociation constants.
Topics: Animals; Batrachotoxins; Cations; Cell Membrane Permeability; Clone Cells; Formamides; Hydrogen-Ion | 1979 |