2,4-dinitrophenol has been researched along with Neuroblastoma in 3 studies
2,4-Dinitrophenol: A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
dinitrophenol : Members of the class of nitrophenol carrying two nitro substituents.
2,4-dinitrophenol : A dinitrophenol having the nitro groups at the 2- and 4-positions.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mouse neuroblastoma cell cultures (Neuro-2a) were exposed to different concentrations of the toxic compounds for 24, 48 and 72 h to study basal toxicity effects (cell proliferation by quantification of total protein content (PR) and relative neutral red uptake (RNRU) by lysosomes)." | 7.69 | Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro. ( Andrés, MI; Repetto, G; Repetto, M; Sanz, P, 1996) |
| " Mouse neuroblastoma cell cultures (Neuro-2a) were exposed to different concentrations of the toxic compounds for 24, 48 and 72 h to study basal toxicity effects (cell proliferation by quantification of total protein content (PR) and relative neutral red uptake (RNRU) by lysosomes)." | 3.69 | Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro. ( Andrés, MI; Repetto, G; Repetto, M; Sanz, P, 1996) |
| " Uptake of [3H]DADLE was a receptor-mediated process, since it was inhibited by opiate receptor ligands and the (i) time course, (ii) dose-response curve, and (iii) temperature dependence of uptake were similar to those for enkephalin-receptor down regulation." | 1.27 | Characterization of the association of tritiated enkephalin with neuroblastoma cells under conditions optimal for receptor down regulation. ( Blanchard, SG; Chang, KJ; Cuatrecasas, P, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Milani, ZH | 1 |
| Ramsden, DB | 1 |
| Parsons, RB | 1 |
| Blanchard, SG | 1 |
| Chang, KJ | 1 |
| Cuatrecasas, P | 1 |
| Andrés, MI | 1 |
| Repetto, G | 1 |
| Sanz, P | 1 |
| Repetto, M | 1 |
3 other studies available for 2,4-dinitrophenol and Neuroblastoma
| Article | Year |
|---|---|
Neuroprotective effects of nicotinamide N-methyltransferase and its metabolite 1-methylnicotinamide.
Topics: 2,4-Dinitrophenol; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; N | 2013 |
Characterization of the association of tritiated enkephalin with neuroblastoma cells under conditions optimal for receptor down regulation.
Topics: 2,4-Dinitrophenol; Animals; Cell Line; Dinitrophenols; Dose-Response Relationship, Drug; Enkephalin, | 1983 |
Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro.
Topics: 2,4-Dinitrophenol; Acetylcholinesterase; Animals; beta-Galactosidase; Cell Division; Dinitrophenols; | 1996 |