Page last updated: 2024-10-18

formaldehyde and Neuroblastoma

formaldehyde has been researched along with Neuroblastoma in 26 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"In this study, we assessed the neuroprotective properties of TongLuoJiuNao (TLJN), a traditional Chinese medicine preparation, against formaldehyde stress in human neuroblastoma cells (SH-SY5Y cell line)."7.79The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde. ( Chen, JY; He, RQ; Hua, Q; Li, J; Liu, KL; Liu, Y; Meng, YY; Mo, WC; Sun, MR; Sun, P; Wang, F, 2013)
"Metastatic neuroblastoma cells in bone marrow aspirates were examined by the formaldehyde induced fluorescence histochemical method."7.66Detection of metastatic neuroblastoma cells in bone marrow aspirates by formaldehyde induced fluorescence histochemistry. ( Fujii, R; Fujisawa, T; Imashuku, S; Mizukawa, K; Otsuka, N, 1983)
"In this study, we assessed the neuroprotective properties of TongLuoJiuNao (TLJN), a traditional Chinese medicine preparation, against formaldehyde stress in human neuroblastoma cells (SH-SY5Y cell line)."3.79The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde. ( Chen, JY; He, RQ; Hua, Q; Li, J; Liu, KL; Liu, Y; Meng, YY; Mo, WC; Sun, MR; Sun, P; Wang, F, 2013)
" Mild formaldehyde crosslinking of mouse neuroblastoma cells (N2a) that are susceptible to prion infection revealed the presence of PrP(C) in high molecular mass (HMM) protein complexes of 200 to 225 kDa."3.71Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. ( Baldwin, MA; Ball, HL; Bosque, PJ; Bradon, N; Cohen, FE; Crossin, KL; DeArmond, SJ; Edelman, GM; Legname, G; Prusiner, SB; Schmitt-Ulms, G, 2001)
"Metastatic neuroblastoma cells in bone marrow aspirates were examined by the formaldehyde induced fluorescence histochemical method."3.66Detection of metastatic neuroblastoma cells in bone marrow aspirates by formaldehyde induced fluorescence histochemistry. ( Fujii, R; Fujisawa, T; Imashuku, S; Mizukawa, K; Otsuka, N, 1983)
" The method is demonstrated by comparing the structure of the plasma membrane of synchronized neuroblastoma cells after glutaraldehyde and formaldehyde fixation at pH 6."3.66Quantitative analysis of the numerical and lateral distribution of intramembrane particles in freeze-fractured biological membranes. ( Bluemink, JG; de Laat, SW; Tertoolen, LG, 1981)
"New platforms for analyzing chromosomal aberrations using formalin-fixed paraffin-embedded (FFPE) tissue have recently been developed."1.43Segmental Chromosomal Aberrations in Localized Neuroblastoma Can be Detected in Formalin-Fixed Paraffin-Embedded Tissue Samples and Are Associated With Recurrence. ( Applebaum, MA; Bagatell, R; Chlenski, A; Cohn, SL; Delattre, O; Gosiengfiao, Y; Irwin, MS; Janoueix-Lerosey, I; Lapouble, E; Little, A; Mayfield, JR; Pinto, N; Raca, G; Rawwas, J; Schleiermacher, G; Sukhanova, M, 2016)
"Formaldehyde is a common environmental contaminant and also a metabolite of methanol."1.34Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells. ( He, RQ; Liu, Y; Nie, CL; Perrett, S; Wang, XS, 2007)
"Nine neuroblastomas were NMYC amplified, and the remaining cases were nonamplified."1.33Assessment of NMYC amplification: a comparison of FISH, quantitative PCR monoplexing and traditional blotting methods used with formalin-fixed, paraffin-embedded neuroblastomas. ( Holden, JA; Layfield, LJ; Shimada, H; Willmore-Payne, C, 2005)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19909 (34.62)18.7374
1990's1 (3.85)18.2507
2000's11 (42.31)29.6817
2010's5 (19.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Somasundaram, DB1
Aravindan, S1
Yu, Z1
Jayaraman, M1
Tran, NTB1
Li, S1
Herman, TS1
Aravindan, N1
Tabyaoui, I1
Tahiri-Jouti, N1
Serhier, Z1
Bennani-Othmani, M1
Sibai, H1
Itri, M1
Benchekroun, S1
Zamiati, S1
Sun, P1
Chen, JY1
Li, J1
Sun, MR1
Mo, WC1
Liu, KL1
Meng, YY1
Liu, Y4
Wang, F1
He, RQ2
Hua, Q2
Chen, J1
Sun, M1
Wang, X1
Lu, J1
Wei, Y2
Tan, Y1
Götz, J1
He, R1
Pinto, N1
Mayfield, JR1
Raca, G1
Applebaum, MA1
Chlenski, A1
Sukhanova, M1
Bagatell, R1
Irwin, MS1
Little, A1
Rawwas, J1
Gosiengfiao, Y1
Delattre, O1
Janoueix-Lerosey, I1
Lapouble, E1
Schleiermacher, G1
Cohn, SL1
Pavone, F1
Luvisetto, S1
Marinelli, S1
Straface, E1
Fabbri, A1
Falzano, L1
Fiorentini, C1
Malorni, W1
Swift, LP1
Cutts, SM2
Rephaeli, A2
Nudelman, A2
Phillips, DR2
Petersen, BL1
Sørensen, MC1
Pedersen, S1
Rasmussen, M1
Layfield, LJ1
Willmore-Payne, C1
Shimada, H1
Holden, JA1
Bonfigli, A1
Zarivi, O1
Colafarina, S1
Cimini, AM1
Ragnelli, AM1
Aimola, P1
Natali, PG1
Cerù, MP1
Amicarelli, F1
Miranda, M1
Behl, B1
Klos, M1
Serr, M1
Ebert, U1
Janson, B1
Drescher, K1
Gross, G1
Schoemaker, H1
Aviel-Ronen, S1
Qi Zhu, C1
Coe, BP1
Liu, N1
Watson, SK1
Lam, WL1
Tsao, MS1
Nie, CL2
Wang, XS1
Perrett, S1
Chen, X1
Liu, YY1
Dui, W1
Davies, MC1
Tendler, SJ1
He, RG1
Triche, TJ1
Askin, FB1
Mizukawa, K1
Fujii, R1
Fujisawa, T1
Otsuka, N1
Imashuku, S1
de Laat, SW2
Tertoolen, LG1
Bluemink, JG1
Gotoh, T1
Sugihara, H1
Matsumura, T1
Katsura, K1
Takamatsu, T1
Sawada, T1
Hmelnitsky, I1
Schmitt-Ulms, G1
Legname, G1
Baldwin, MA1
Ball, HL1
Bradon, N1
Bosque, PJ1
Crossin, KL1
Edelman, GM1
DeArmond, SJ1
Cohen, FE1
Prusiner, SB1
Gonoi, T1
Hille, B1
van den Eijnden-van Raaij, AJ1
van Maurik, P1
Boonstra, J1
van Zoelen, EJ1
Whelan, JP1
Chatten, J1
Lampson, LA1
Kurnit, DM1
Schildkraut, CL1
Maio, JJ1
Narotzky, R1
Bondareff, W1
Hermetet, JC1
Ciesielski-Treska, J1
Mandel, P1

Other Studies

26 other studies available for formaldehyde and Neuroblastoma

ArticleYear
Droplet digital PCR as an alternative to FISH for MYCN amplification detection in human neuroblastoma FFPE samples.
    BMC cancer, 2019, Jan-28, Volume: 19, Issue:1

    Topics: Biomarkers, Tumor; Formaldehyde; Gene Amplification; Humans; Immunohistochemistry; In Situ Hybridiza

2019
Immunohistochemical expression of CD44s in human neuroblastic tumors: Moroccan experience and highlights on current data.
    Diagnostic pathology, 2013, Feb-27, Volume: 8

    Topics: Adolescent; Biomarkers, Tumor; Cell Differentiation; Chi-Square Distribution; Child; Child, Preschoo

2013
The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde.
    BMC complementary and alternative medicine, 2013, Jul-01, Volume: 13

    Topics: Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Drugs, Chinese Herbal; Formaldehyde; Humans; Irid

2013
The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells.
    Science China. Life sciences, 2014, Volume: 57, Issue:4

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Central Nervous System; Chromatography, High Pr

2014
Segmental Chromosomal Aberrations in Localized Neuroblastoma Can be Detected in Formalin-Fixed Paraffin-Embedded Tissue Samples and Are Associated With Recurrence.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:6

    Topics: Child; Child, Preschool; Chromosome Aberrations; Disease-Free Survival; Female; Formaldehyde; Humans

2016
The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating mu-opioid receptors.
    Pain, 2009, Volume: 145, Issue:1-2

    Topics: Analgesics; Animals; Bacterial Toxins; Cell Line, Tumor; Cerebellum; Disease Models, Animal; Dose-Re

2009
Activation of adriamycin by the pH-dependent formaldehyde-releasing prodrug hexamethylenetetramine.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:2

    Topics: Antineoplastic Agents; Biotransformation; DNA Adducts; DNA, Neoplasm; Doxorubicin; Formaldehyde; Hum

2003
Fluorescence in situ hybridization on formalin-fixed and paraffin-embedded tissue: optimizing the method.
    Applied immunohistochemistry & molecular morphology : AIMM, 2004, Volume: 12, Issue:3

    Topics: Chromosome Aberrations; Fixatives; Formaldehyde; Genes, myc; Humans; Hyperplasia; In Situ Hybridizat

2004
Assessment of NMYC amplification: a comparison of FISH, quantitative PCR monoplexing and traditional blotting methods used with formalin-fixed, paraffin-embedded neuroblastomas.
    Analytical and quantitative cytology and histology, 2005, Volume: 27, Issue:1

    Topics: Blotting, Southern; Cell Line, Tumor; Child; Female; Formaldehyde; Gene Amplification; Genes, myc; G

2005
Human glioblastoma ADF cells express tyrosinase, L-tyrosine hydroxylase and melanosomes and are sensitive to L-tyrosine and phenylthiourea.
    Journal of cellular physiology, 2006, Volume: 207, Issue:3

    Topics: Apoptosis; Caspase 9; Caspases; Cell Line, Tumor; Formaldehyde; Gene Expression Regulation, Enzymolo

2006
An ELISA-based method for the quantification of incorporated BrdU as a measure of cell proliferation in vivo.
    Journal of neuroscience methods, 2006, Nov-15, Volume: 158, Issue:1

    Topics: Animals; Brain; Bromodeoxyuridine; Cell Count; Cell Line, Tumor; Cell Proliferation; DNA; Dose-Respo

2006
Large fragment Bst DNA polymerase for whole genome amplification of DNA from formalin-fixed paraffin-embedded tissues.
    BMC genomics, 2006, Dec-12, Volume: 7

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA-Directed DNA Polymerase; DNA, Neoplasm; Formal

2006
Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells.
    BMC neuroscience, 2007, Jan-23, Volume: 8

    Topics: Amyloid; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Formaldehyde; Humans; Neurob

2007
Formaldehyde at low concentration induces protein tau into globular amyloid-like aggregates in vitro and in vivo.
    PloS one, 2007, Jul-18, Volume: 2, Issue:7

    Topics: Acetaldehyde; Amyloid; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Formaldehyde; Hi

2007
Neuroblastoma and the differential diagnosis of small-, round-, blue-cell tumors.
    Human pathology, 1983, Volume: 14, Issue:7

    Topics: Cartilage Oligomeric Matrix Protein; Child; Child, Preschool; Culture Techniques; Diagnosis, Differe

1983
Detection of metastatic neuroblastoma cells in bone marrow aspirates by formaldehyde induced fluorescence histochemistry.
    Acta medica Okayama, 1983, Volume: 37, Issue:5

    Topics: Bone Marrow; Bone Marrow Examination; Catecholamines; Formaldehyde; Histocytochemistry; Humans; Micr

1983
Quantitative analysis of the numerical and lateral distribution of intramembrane particles in freeze-fractured biological membranes.
    European journal of cell biology, 1981, Volume: 23, Issue:2

    Topics: Animals; Cell Line; Cell Membrane; Cytological Techniques; Fixatives; Formaldehyde; Freeze Fracturin

1981
Human neuroblastoma demonstrating clonal evolution in vivo.
    Genes, chromosomes & cancer, 1998, Volume: 22, Issue:1

    Topics: Child, Preschool; Clone Cells; Formaldehyde; Humans; In Situ Hybridization, Fluorescence; Kidney Neo

1998
Molecular basis for the synergistic interaction of adriamycin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9).
    Cancer research, 2001, Nov-15, Volume: 61, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Breast Neoplasms;

2001
Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein.
    Journal of molecular biology, 2001, Dec-14, Volume: 314, Issue:5

    Topics: Alternative Splicing; Amidohydrolases; Amino Acid Sequence; Animals; Binding Sites; Caveolae; Cross-

2001
Gating of Na channels. Inactivation modifiers discriminate among models.
    The Journal of general physiology, 1987, Volume: 89, Issue:2

    Topics: Acetamides; Animals; Cell Line; Formaldehyde; Ion Channels; Marine Toxins; Models, Biological; Neuro

1987
Ultrastructural localization of platelet-derived growth factor and related factors in normal and transformed cells.
    Experimental cell research, 1988, Volume: 178, Issue:2

    Topics: Acrolein; Animals; Cell Line; Cell Line, Transformed; Detergents; Fibroblasts; Fixatives; Fluorescen

1988
HLA class I and beta 2-microglobulin expression in frozen and formaldehyde-fixed paraffin sections of neuroblastoma tumors.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 2

    Topics: beta 2-Microglobulin; Child; Child, Preschool; Female; Formaldehyde; Frozen Sections; Histological T

1985
Single-strand interactions of mouse satellite DNA.
    Biochimica et biophysica acta, 1972, Feb-15, Volume: 259, Issue:3

    Topics: Animals; Base Sequence; Cell Nucleus; Centrifugation, Density Gradient; Culture Techniques; Deoxyrib

1972
Biogenic amines in cultured neuroblastoma and astrocytoma cells.
    The Journal of cell biology, 1974, Volume: 63, Issue:1

    Topics: Animals; Astrocytoma; Biogenic Amines; Carbon Radioisotopes; Cell Line; Cells, Cultured; Clone Cells

1974
Cytochemical demonstration of catecholamines and acetylcholinesterase activity in neuroblastoma cells in culture.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1972, Volume: 20, Issue:2

    Topics: Acetylcholinesterase; Animals; Catecholamines; Cell Line; Cells, Cultured; Fluorescence; Formaldehyd

1972