isoflurophate has been researched along with Neuroblastoma in 18 studies
Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this work we studied sensitivity to the non-neuropathic OP paraoxon and to the neuropathic OP mipafox of phenyl valerate esterases (PVases) in intact and lysed human neuroblastoma SH-SY5Y cells." | 7.88 | Hydrolyzing activities of phenyl valerate sensitive to organophosphorus compounds paraoxon and mipafox in human neuroblastoma SH-SY5Y cells. ( Del Río, E; Estévez, J; González-González, M; Sogorb, MA; Vilanova, E, 2018) |
| "The objective of this study was to evaluate the comparative non-cholinergic neurotoxic effects of paraoxon, which is acutely neurotoxic, and diisopropyl fluorophosphate (DFP), which induces OPIDN, in the human neuroblastoma SY5Y and the human astrocytoma cell line CCF-STTG1." | 7.74 | Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines. ( Barhoumi, R; Datta, A; Pal, R; Qian, Y; Tiffany-Castiglioni, E; Venkatraj, J; Wild, JR, 2007) |
| " We report here the isolation of a serine protease from serum-free conditioned medium of human neuroblastoma cells." | 7.74 | Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide. ( Abraham, CR; Bagchi, S; Hildebrant, R; Scaloni, A; Widom, RL; Yamin, R, 2007) |
| " In this work we studied sensitivity to the non-neuropathic OP paraoxon and to the neuropathic OP mipafox of phenyl valerate esterases (PVases) in intact and lysed human neuroblastoma SH-SY5Y cells." | 3.88 | Hydrolyzing activities of phenyl valerate sensitive to organophosphorus compounds paraoxon and mipafox in human neuroblastoma SH-SY5Y cells. ( Del Río, E; Estévez, J; González-González, M; Sogorb, MA; Vilanova, E, 2018) |
| "The objective of this study was to evaluate the comparative non-cholinergic neurotoxic effects of paraoxon, which is acutely neurotoxic, and diisopropyl fluorophosphate (DFP), which induces OPIDN, in the human neuroblastoma SY5Y and the human astrocytoma cell line CCF-STTG1." | 3.74 | Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines. ( Barhoumi, R; Datta, A; Pal, R; Qian, Y; Tiffany-Castiglioni, E; Venkatraj, J; Wild, JR, 2007) |
| " We report here the isolation of a serine protease from serum-free conditioned medium of human neuroblastoma cells." | 3.74 | Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide. ( Abraham, CR; Bagchi, S; Hildebrant, R; Scaloni, A; Widom, RL; Yamin, R, 2007) |
| " SY5Y human neuroblastoma cells were used as a model test system, as these cells respond distinctly to mipafox, which produces OP-induced delayed neuropathy, and paraoxon, which does not." | 3.73 | Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH). ( Cho, TM; Donnelly, KC; Tiffany-Castiglioni, E; Wild, JR, 2006) |
| "Phenylmethylsulfonyl fluoride (PMSF) was included as a non-neuropathic inhibitor of NTE." | 1.33 | Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells. ( Ehrich, M; Jortner, BS; Knight, K; Massicotte, C; Van der Schyf, CJ, 2005) |
| "Mipafox and paraoxon were used as OP models that respectively do and do not induce OPIDN." | 1.32 | Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds. ( Barhoumi, R; Burghardt, RC; Donnelly, KC; Hong, MS; Hong, SJ; Tiffany-Castiglioni, E; Venkatraj, V; Wild, JR, 2003) |
| " BaP was the most toxic of all PAHs tested, and anthracene failed to produce a toxic response at any concentration tested." | 1.32 | Neurotoxicity of polycyclic aromatic hydrocarbons and simple chemical mixtures. ( Donnelly, KC; Mumtaz, MM; Tang, Y; Tiffany-Castiglioni, E, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-González, M | 1 |
| Estévez, J | 1 |
| Del Río, E | 1 |
| Vilanova, E | 1 |
| Sogorb, MA | 1 |
| Ehrich, M | 4 |
| Van Tassell, R | 1 |
| Li, Y | 1 |
| Zhou, Z | 1 |
| Kepley, CL | 1 |
| Hong, MS | 1 |
| Hong, SJ | 2 |
| Barhoumi, R | 2 |
| Burghardt, RC | 1 |
| Donnelly, KC | 3 |
| Wild, JR | 3 |
| Venkatraj, V | 1 |
| Tiffany-Castiglioni, E | 5 |
| Tang, Y | 1 |
| Mumtaz, MM | 1 |
| Cho, T | 1 |
| Massicotte, C | 1 |
| Knight, K | 1 |
| Van der Schyf, CJ | 1 |
| Jortner, BS | 1 |
| Chang, PA | 1 |
| Chen, R | 1 |
| Wu, YJ | 1 |
| Cho, TM | 1 |
| Qian, Y | 1 |
| Venkatraj, J | 1 |
| Pal, R | 1 |
| Datta, A | 1 |
| Yamin, R | 1 |
| Bagchi, S | 1 |
| Hildebrant, R | 1 |
| Scaloni, A | 1 |
| Widom, RL | 1 |
| Abraham, CR | 1 |
| Gibson, WH | 1 |
| Burack, SL | 1 |
| Picciano, A | 1 |
| Gilbert, LC | 1 |
| Wachsman, JT | 2 |
| Kimhi, Y | 1 |
| Mahler, A | 1 |
| Saya, D | 1 |
| Rohde, BH | 1 |
| Chiou, GC | 1 |
| Intropido, L | 1 |
| Costa, LG | 1 |
| Nostrandt, AC | 1 |
| Snider, RM | 1 |
| McKinney, M | 1 |
| Richelson, E | 1 |
| Biedler, JL | 1 |
18 other studies available for isoflurophate and Neuroblastoma
| Article | Year |
|---|---|
Hydrolyzing activities of phenyl valerate sensitive to organophosphorus compounds paraoxon and mipafox in human neuroblastoma SH-SY5Y cells.
Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hydrolysis; Isoflurophate; Neuroblastoma | 2018 |
Fullerene antioxidants decrease organophosphate-induced acetylcholinesterase inhibition in vitro.
Topics: Acetylcholinesterase; Animals; Antioxidants; Brain; Cell Line, Tumor; Cell Survival; Cells, Cultured | 2011 |
Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds.
Topics: Calcium; Dose-Response Relationship, Drug; Homeostasis; Humans; Isoflurophate; Neurites; Neuroblasto | 2003 |
Neurotoxicity of polycyclic aromatic hydrocarbons and simple chemical mixtures.
Topics: Amino Acids; Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions | 2003 |
Neurofilament 200 as an indicator of differences between mipafox and paraoxon sensitivity in Sy5Y neuroblastoma cells.
Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Insecticides; Isoflurophate; Nerve Growt | 2004 |
Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Cholinesterase Inhibitors; Dose-Resp | 2005 |
Reduction of neuropathy target esterase does not affect neuronal differentiation, but moderate expression induces neuronal differentiation in human neuroblastoma (SK-N-SH) cell line.
Topics: Acetylcholinesterase; Animals; Antineoplastic Agents; Carboxylic Ester Hydrolases; Cell Differentiat | 2005 |
Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH).
Topics: Acetylcholinesterase; Biodegradation, Environmental; Carboxylic Ester Hydrolases; Cell Line, Tumor; | 2006 |
Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines.
Topics: Astrocytoma; Blotting, Western; Calcium; Cell Line, Tumor; Cytosol; Endoplasmic Reticulum Chaperone | 2007 |
Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide.
Topics: Acyltransferases; Amyloid beta-Peptides; Animals; Autoradiography; Cell Line; Chlorocebus aethiops; | 2007 |
The effects of serine protease inhibitors on morphological differentiation of murine neuroblastoma cells (NB15).
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Antipain; Cell Differentiation; Cyc | 1984 |
Characterization and partial purification of the plasminogen activator from human neuroblastoma cell line, SK-N-SH. A comparison with human urokinase.
Topics: Ammonium Sulfate; Cell Line; Chromatography, Affinity; Endopeptidases; Fibrin; Humans; Isoelectric P | 1982 |
Acetylcholinesterase in mouse neuroblastoma cells: intracellular and released enzyme.
Topics: Acetylcholinesterase; Animals; Cell Line; Clone Cells; Electrophoresis, Polyacrylamide Gel; Isofluro | 1980 |
Use of C1300 neuroblastoma cells to evaluate the protective value of hexamethonium, trimethaphan, hemicholinium, and triethylcholine against diisopropyl phosphorofluoridate toxicity.
Topics: Animals; Cell Survival; Choline; Cholinergic Antagonists; Cholinesterase Reactivators; DNA, Neoplasm | 1995 |
Interaction of organophosphorus compounds with muscarinic receptors in SH-SY5Y human neuroblastoma cells.
Topics: Carbachol; Humans; Inositol Phosphates; Insecticides; Isoflurophate; Neuroblastoma; Organophosphorus | 1994 |
Modification of mipafox-induced inhibition of neuropathy target esterase in neuroblastoma cells of human origin.
Topics: Aldicarb; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Humans; Isoflurophate; Nerve Growth | 1993 |
Thrombin binding and stimulation of cyclic guanosine monophosphate formation in neuroblastoma cells.
Topics: Animals; Binding Sites; Cerebral Cortex; Clone Cells; Cyclic GMP; Humans; In Vitro Techniques; Isofl | 1986 |
Fibrinolytic activity associated with human neuroblastoma cells.
Topics: Blood; Cell Line; Cells, Cultured; Culture Media; Fibrinolysis; Fibroblasts; Humans; In Vitro Techni | 1974 |