Page last updated: 2024-10-23

bumetanide and Neuroblastoma

bumetanide has been researched along with Neuroblastoma in 4 studies

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" The cotransporter activity in human neuroblastoma SH-SY5Y cells was assessed by bumetanide-sensitive K+ influx, and protein expression was evaluated by Western blot analysis."3.70Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate. ( Murali, SG; Sun, D, 1998)
"Amiloride and mannitol were found effective in reducing the lactic acidosis-induced cellular swelling."1.29Mechanism of cellular swelling induced by extracellular lactic acidosis in neuroblastoma-glioma hybrid (NG108-15) cells. ( Alojado, ME; Kemmotsu, O; Morimoto, Y, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alojado, ME1
Morimoto, Y2
Kemmotsu, O1
Sun, D1
Murali, SG1
O'Reilly, N1
Xia, Z1
Fiander, H1
Tauskela, J1
Small, DL1
Babila, T1
Gottlieb, Y1
Lutz, RA1
Lichtstein, D1

Other Studies

4 other studies available for bumetanide and Neuroblastoma

ArticleYear
Mechanism of cellular swelling induced by extracellular lactic acidosis in neuroblastoma-glioma hybrid (NG108-15) cells.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:5

    Topics: Acidosis, Lactic; Amiloride; Animals; Bumetanide; Cell Size; Cytological Techniques; Diuretics; Diur

1996
Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Bumetanide; Carrier Proteins; Cycloleucine

1998
Disparity between ionic mediators of volume regulation and apoptosis in N1E 115 mouse neuroblastoma cells.
    Brain research, 2002, Jul-12, Volume: 943, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

2002
A bumetanide-sensitive, potassium carrier-mediated transport system in excitable tissues.
    Life sciences, 1989, Volume: 44, Issue:22

    Topics: Animals; Binding Sites; Biological Transport; Brain; Bumetanide; Cell Line; Cell Membrane; Chick Emb

1989