Page last updated: 2024-10-30

beta-lapachone and Neuroblastoma

beta-lapachone has been researched along with Neuroblastoma in 2 studies

beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shin, BH1
Lim, Y1
Oh, HJ1
Park, SM1
Lee, SK1
Ahnn, J1
Kim, DH1
Song, WK1
Kwak, TH1
Park, WJ1
Nukuzuma, S1
Nakamichi, K1
Kameoka, M1
Sugiura, S1
Nukuzuma, C1
Tasaki, T1
Takegami, T1

Other Studies

2 other studies available for beta-lapachone and Neuroblastoma

ArticleYear
Pharmacological activation of Sirt1 ameliorates polyglutamine-induced toxicity through the regulation of autophagy.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Adenine; Animals; Animals, Genetically Modified; Apoptosis; Autophagy; Blotting, Western; Caenorhabd

2013
Suppressive effect of topoisomerase inhibitors on JC polyomavirus propagation in human neuroblastoma cells.
    Microbiology and immunology, 2016, Volume: 60, Issue:4

    Topics: Antiviral Agents; Cell Line; Cell Proliferation; DNA Replication; DNA, Viral; Humans; JC Virus; Leuk

2016