ethylmaleimide has been researched along with Neuroblastoma in 17 studies
Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of murine neuroblastoma N18 cells with N-ethylmaleimide under conditions that favor diminution of membrane potential leads to a 65% increase in the rate of veratridine-stimulated, tetrodotoxin-sensitive Na+ uptake and to a 50% decrease in the concentration of veratridine required for half-maximal stimulation." | 7.66 | Effects of N-ethylmaleimide treatment on the action potential Na+-ionophore of cultured neuroblastoma cells. ( Blumenthal, K; Panini, A, 1980) |
| " In this study we investigated the relationship between these two phenomena during olomoucine- and roscovitin-induced apoptosis in human lung cancer and neuroblastoma cell lines." | 3.69 | Plasma membrane alterations and cytoskeletal changes in apoptosis. ( Kuijpers, HJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; van Engeland, M, 1997) |
| "Accumulation of inositol phosphates in NG108-15 neuroblastoma x glioma hybrid cells, pre-labeled for 24h to equilibrium, was stimulated by bradykinin, guanosine 5'-O-(3-thiotriphosphate) and the diacylglycerol kinase inhibitor R59022." | 3.67 | Effects of bradykinin, GTP gamma S, R59022 and N-ethylmaleimide on inositol phosphate production in NG108-15 cells. ( Chiang, CF; Hauser, G, 1989) |
| "Treatment of murine neuroblastoma N18 cells with N-ethylmaleimide under conditions that favor diminution of membrane potential leads to a 65% increase in the rate of veratridine-stimulated, tetrodotoxin-sensitive Na+ uptake and to a 50% decrease in the concentration of veratridine required for half-maximal stimulation." | 3.66 | Effects of N-ethylmaleimide treatment on the action potential Na+-ionophore of cultured neuroblastoma cells. ( Blumenthal, K; Panini, A, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Panini, A | 1 |
| Blumenthal, K | 1 |
| Larsen, NE | 3 |
| Mullikin-Kilpatrick, D | 3 |
| Blume, AJ | 3 |
| Kassis, S | 1 |
| Hagmann, J | 1 |
| Fishman, PH | 1 |
| Chang, PP | 1 |
| Moss, J | 1 |
| Quandt, FN | 1 |
| Kato, E | 1 |
| Narahashi, T | 1 |
| Smith, MM | 1 |
| Harden, TK | 1 |
| Gérard, V | 1 |
| Rouzaire-Dubois, B | 1 |
| Dubois, JM | 1 |
| van Engeland, M | 1 |
| Kuijpers, HJ | 1 |
| Ramaekers, FC | 1 |
| Reutelingsperger, CP | 1 |
| Schutte, B | 1 |
| Nah, SY | 1 |
| Unteutsch, A | 1 |
| Bunzow, JR | 1 |
| Cook, SP | 1 |
| Beacham, DW | 1 |
| Grandy, DK | 1 |
| Evans, JR | 1 |
| Bielefeldt, K | 1 |
| Kasai, H | 1 |
| Sakurada, C | 1 |
| Ohgaki, Y | 1 |
| Yokosawa, H | 3 |
| Ishii, S | 3 |
| Costa, T | 1 |
| Herz, A | 1 |
| Satoh, M | 2 |
| Chiang, CF | 1 |
| Hauser, G | 1 |
1 review available for ethylmaleimide and Neuroblastoma
| Article | Year |
|---|---|
Involvement of sulfhydryl groups in the functional integrity of the opiate receptors of neuroblastoma x glioma hybrid NG108-15.
Topics: Animals; Enkephalins; Ethylmaleimide; Glioma; Hybrid Cells; Kinetics; Mice; Neoplasms, Experimental; | 1983 |
16 other studies available for ethylmaleimide and Neuroblastoma
| Article | Year |
|---|---|
Effects of N-ethylmaleimide treatment on the action potential Na+-ionophore of cultured neuroblastoma cells.
Topics: Action Potentials; Animals; Cells, Cultured; Ethylmaleimide; Ion Channels; Ionophores; Mice; Neoplas | 1980 |
Two different modifications of the neuroblastoma X glioma hybrid opiate receptors induced by N-ethylmaleimide.
Topics: Animals; Ethylmaleimide; Glioma; Hybrid Cells; Kinetics; Membranes; Mice; Naltrexone; Neuroblastoma; | 1981 |
Mechanism of action of cholera toxin on intact cells. Generation of A1 peptide and activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Cyclic AMP; Electrophoresis, Polyacrylamide Ge | 1982 |
Protection of opiate receptors in NG108-15 against modification by N-ethylmaleimide.
Topics: Animals; Cell Line; Dithiothreitol; Enkephalin, Methionine; Ethylmaleimide; Glioma; Hybrid Cells; Ki | 1983 |
Effects of methylmercury on electrical responses of neuroblastoma cells.
Topics: Acetylcholine; Action Potentials; Animals; Cell Line; Dithiothreitol; Ethylmaleimide; Ion Channels; | 1982 |
Modification of receptor-mediated inhibition of adenylate cyclase in NG108-15 neuroblastoma X glioma cells by n-ethylmaleimide.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Epinephrine; Ethylmaleimide; Glioma; GTP-Binding Pr | 1984 |
Contribution of a H+ pump in determining the resting potential of neuroblastoma cells.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell M | 1994 |
Plasma membrane alterations and cytoskeletal changes in apoptosis.
Topics: Actins; Annexin A5; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Membrane; Chromatin; Cytoskeleto | 1997 |
Mu and delta opioids but not kappa opioid inhibit voltage-activated Ba2+ currents in neuronal F-11 cell.
Topics: Analgesics; Analgesics, Opioid; Animals; Barium; Calcium; Calcium Channel Blockers; Dose-Response Re | 1997 |
Regulation of sodium currents through oxidation and reduction of thiol residues.
Topics: Animals; Cell Membrane; Disulfides; Dithiothreitol; Ethylmaleimide; Glutathione; Humans; Membrane Po | 2000 |
Tonic inhibition and rebound facilitation of a neuronal calcium channel by a GTP-binding protein.
Topics: Animals; Calcium Channels; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylmaleimide; GTP-Bind | 1991 |
Thiol-dependent membrane-bound metallo-endopeptidase functioning in degradation of luteinizing hormone-releasing hormone in neuroblastoma cells and rat brain synaptic membrane. Isolation and characterization.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Brain; Cell Line; Cell Membrane; Chromatography, Affinity; | 1990 |
Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins.
Topics: Animals; Benzomorphans; Cell Line; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine | 1989 |
Characterization of cysteine proteases functioning in degradation of dynorphin in neuroblastoma cells: evidence for the presence of a novel enzyme with strict specificity toward paired basic residues.
Topics: Animals; Cell Line; Chloromercuribenzoates; Chromatography, Gel; Chromatography, High Pressure Liqui | 1989 |
Effects of bradykinin, GTP gamma S, R59022 and N-ethylmaleimide on inositol phosphate production in NG108-15 cells.
Topics: Animals; Bradykinin; Cell Line; Drug Interactions; Ethylmaleimide; Glioma; Guanosine 5'-O-(3-Thiotri | 1989 |
Degradation of dynorphin-(1-13) and dynorphin-(1-17) by the neuroblastoma cell membrane. Evidence for the involvement of a cysteine protease.
Topics: Amino Acids; Captopril; Cell Line; Cysteine Endopeptidases; Dynorphins; Endopeptidases; Enkephalin, | 1986 |