dihydroactinidiolide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

dihydroactinidiolide: secretion in tail scent gland of red fox; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	6432173
CHEMBL ID	2271637
SCHEMBL ID	2186328
MeSH ID	M0056429

Synonyms (39)

Synonym
nsc-357087
actinidiolide, dihydro-
17092-92-1
dihydroactinidiolide
2(4h)-benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (r)-
(7ar)-4,4,7a-trimethyl-6,7-dihydro-5h-1-benzofuran-2-one
A811266
(7ar)-4,4,7a-trimethyl-6,7-dihydro-5h-benzofuran-2-one;dihydroactinidiolide
nsc 357087
o3m4862r3r ,
2(4h)-benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- (van)
unii-o3m4862r3r
S3962
CHEMBL2271637
d-dihydroactinidiolide
(r)-dihydroactinidiolide
dihydroactinidiolide (r)-form [mi]
(-)-dihydroactinidiolide
dihydroactinidiolide, (-)-
2(4h)-benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (7ar)-
SCHEMBL2186328
W-108036
4,4,7a-trimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4h)-one, (r)-
IMKHDCBNRDRUEB-LLVKDONJSA-N
5,6,7,7a-tetrahydro-4,4-7a-trimethyl-2-(4h)-benzofuranone
AKOS028109299
dihydroactinidolide
r-(-)dihydro actinidiolide
Q5276417
E77016
r-dihydroactinidiolide
(r)-4,4,7a-trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4h)-one
mfcd20926295
CCG-266435
CS-0030680
HY-107805
SB45270
DTXSID801028845
dihydroactinidiolide (r)-form

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay ID	Title	Year	Journal	Article
AID1101945	Inhibition of intact Triticum aestivum (wheat) seed germination assessed as appearance of distinct rootlets at 500 ppm after 4 days relative to wheat grains RL4137 germination	2002	Journal of agricultural and food chemistry, Oct-23, Volume: 50, Issue:22	Germination and growth inhibitors from wheat (Triticum aestivum L.) husks.
AID1101947	Growth inhibition of intact Triticum aestivum (wheat) seed assessed as appearance of distinct rootlets at 500 ppm after 4 days relative to wheat grains RL4137 germination	2002	Journal of agricultural and food chemistry, Oct-23, Volume: 50, Issue:22	Germination and growth inhibitors from wheat (Triticum aestivum L.) husks.
AID1101944	Inhibition of intact Triticum aestivum (wheat) seed germination assessed as appearance of sprouts at 500 ppm after 4 days relative to wheat grains RL4137 germination	2002	Journal of agricultural and food chemistry, Oct-23, Volume: 50, Issue:22	Germination and growth inhibitors from wheat (Triticum aestivum L.) husks.
AID1101946	Growth inhibition of intact Triticum aestivum (wheat) seed assessed as appearance of sprouts at 500 ppm after 4 days relative to wheat grains RL4137 germination	2002	Journal of agricultural and food chemistry, Oct-23, Volume: 50, Issue:22	Germination and growth inhibitors from wheat (Triticum aestivum L.) husks.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (11.11)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (33.33)	29.6817
2010's	2 (22.22)	24.3611
2020's	3 (33.33)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 32.10

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	32.10 (24.57)
Research Supply Index	2.30 (2.92)
Research Growth Index	4.73 (4.65)
Search Engine Demand Index	39.34 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (32.10)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
4-vinylguaiacol 2-methoxy-4-vinylphenol: a germination inhibitor; also an odorant in green tea; structure in first source. 2-methoxy-4-vinylphenol : A member of the class of phenols that is guaiacol in which the hydrogen para- to the hydroxy group is replaced by a vinyl group.	2.01	1	phenols	flavouring agent; pheromone; plant metabolite
caprylic aldehyde caprylic aldehyde: structure in Merck Index, 9th ed, #1765. octanal : A saturated fatty aldehyde formally arising from reduction of the carboxy group of caprylic acid (octanoic acid).	2.31	1	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	plant metabolite
phenylethyl alcohol Phenylethyl Alcohol: An antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.. 2-phenylethanol : A primary alcohol that is ethanol substituted by a phenyl group at position 2.	2.01	1	benzenes; primary alcohol	Aspergillus metabolite; fragrance; plant growth retardant; plant metabolite; Saccharomyces cerevisiae metabolite
n-hexanal [no description available]	2.31	1	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	human urinary metabolite
methylphenyl carbinol 1-phenylethanol : An aromatic alcohol that is ethanol substituted by a phenyl group at position 1.. methylbenzyl alcohol : Members of the class of benzyl alcohols substituted by at least one methyl group.	2.01	1	aromatic alcohol	mouse metabolite
pentanal pentanal : A saturated fatty aldehyde composed from five carbons in a straight chain.	2.31	1	saturated fatty aldehyde	plant metabolite
beta-cyclocitral beta-cyclocitral: structure in first source. beta-cyclocitral : A monoterpenoid formally derived from citral by cyclisation. It is a volatile compound produced by a cyanobacteria.	2.31	1	monoterpenoid	bacterial metabolite
4-vinylphenol 4-vinylphenol: RN given refers to cpd with locants as specified. 4-hydroxystyrene : A member of the class of phenols that is styrene carrying a hydroxy substituent at position 4.	2.01	1	phenols	human urinary metabolite; human xenobiotic metabolite
benzofurans Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.	3.56	8
beta-ionone beta-ionone: stimulator of carotenogenesis; carotenoid inhibitor; intermediate in synthesis of Vit A; RN given refers to cpd without isomeric designation; structure. beta-ionone : An ionone that is but-3-en-2-one substituted by a 2,6,6-trimethylcyclohex-1-en-1-yl group at position 4.	2.52	2	ionone	antioxidant; fragrance
beta carotene beta Carotene: A carotenoid that is a precursor of VITAMIN A. Beta carotene is administered to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (PORPHYRIA, ERYTHROPOIETIC).. provitamin A : A provitamin that can be converted into vitamin A by enzymes from animal tissues.	2.8	3	carotenoid beta-end derivative; cyclic carotene	antioxidant; biological pigment; cofactor; ferroptosis inhibitor; human metabolite; mouse metabolite; plant metabolite; provitamin A
scopolamine hydrobromide [no description available]	2.31	1

Condition	Relationship Strength	Studies
Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)	7.31	1
Amnesia-Memory Loss [description not available]	2.31	1
Amnesia Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)	7.31	1
Extravascular Hemolysis [description not available]	2.17	1
Hemolysis The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.	2.17	1

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