albonoursin and Neuroblastoma

albonoursin has been researched along with Neuroblastoma* in 1 studies

Other Studies

1 other study(ies) available for albonoursin and Neuroblastoma

Article	Year
Isolation of streptonigrin and its novel derivative from Micromonospora as inducing agents of p53-dependent cell apoptosis. Journal of natural products, 2002, Volume: 65, Issue:5 Streptonigrin (1) and its novel natural derivative 7-(1-methyl-2-oxopropyl)streptonigrin (2) were isolated from an actinomycete strain, Micromonospora sp. IM 2670. The inductions for 1 and 2 are more potent in the human neuroblastoma SH-SY5Y cells that contain wild-type p53 than in SH-SY5Y-5.6 cells that overexpress a dominant negative mutant of p53, thus suggesting that they induce apoptosis through a p53-dependent pathway. Topics: Apoptosis; Cell Nucleus; Chromatography, High Pressure Liquid; Genes, p53; Humans; Inhibitory Concentration 50; Micromonospora; Molecular Conformation; Molecular Structure; Neuroblastoma; Nuclear Magnetic Resonance, Biomolecular; Streptonigrin; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2002

Article

Year

Isolation of streptonigrin and its novel derivative from Micromonospora as inducing agents of p53-dependent cell apoptosis.

Journal of natural products, 2002, Volume: 65, Issue:5

Streptonigrin (1) and its novel natural derivative 7-(1-methyl-2-oxopropyl)streptonigrin (2) were isolated from an actinomycete strain, Micromonospora sp. IM 2670. The inductions for 1 and 2 are more potent in the human neuroblastoma SH-SY5Y cells that contain wild-type p53 than in SH-SY5Y-5.6 cells that overexpress a dominant negative mutant of p53, thus suggesting that they induce apoptosis through a p53-dependent pathway.

Topics: Apoptosis; Cell Nucleus; Chromatography, High Pressure Liquid; Genes, p53; Humans; Inhibitory Concentration 50; Micromonospora; Molecular Conformation; Molecular Structure; Neuroblastoma; Nuclear Magnetic Resonance, Biomolecular; Streptonigrin; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002