pyrazines has been researched along with Neuroblastoma in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 15 (55.56) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Bamodu, OA; Chao, TY; Haryana, SM; Hsiao, M; Hsu, WM; Liu, YL; Pikatan, NW; Yeh, CT | 1 |
| Anwar, A; Hussain, SS; Ishaq, M; Khan, NA; Minhaz, A; Shah, MR; Simjee, SU | 1 |
| Buck, SA; Caldwell, JT; Edwards, H; Ge, Y; Qing, WY; Taub, JW; Wang, G; Wang, Z | 1 |
| Domenicotti, C; Fenoglio, D; Furfaro, AL; Marinari, UM; Moretta, L; Nitti, M; Parodi, A; Passalacqua, M; Piras, S; Pronzato, MA; Traverso, N | 1 |
| Cohen, P | 1 |
| Eksborg, S; Eriksson, E; Johnsen, JI; Kogner, P; Perup, LS; Sävendahl, L; Wickström, M | 1 |
| Becherini, P; Brignole, C; Cilli, M; Cossu, I; Destefanis, E; Di Paolo, D; Emionite, L; Giacomini, A; Loi, M; Pastorino, F; Perri, P; Piaggio, F; Ponzoni, M | 1 |
| Cao, C; Cui, H; Han, S; Jia, Z; Wang, Y; Xu, Y; Yan, Y; Zhao, J; Zhou, N | 1 |
| Baryawno, N; Calero, R; Darabi, A; Dyberg, C; Einvik, C; Johnsen, JI; Kogner, P; Kool, M; Milosevic, J; Sandén, E; Siesjö, P; Sveinbjörnsson, B; Wickström, M | 1 |
| Boyault, S; Brejon, S; Combaret, V; Iacono, I; Puisieux, A; Rousseau, R | 1 |
| Armstrong, MB; Castle, VP; Mody, R; Opipari, AW; Schumacher, KR; Yanik, GA | 1 |
| Brignole, C; Carosio, R; Cilli, M; Di Paolo, D; Galietta, LJ; Loi, M; Marimpietri, D; Nico, B; Pagnan, G; Pastorino, F; Pezzolo, A; Piccardi, F; Pistoia, V; Ponzoni, M; Ribatti, D | 1 |
| Haane, C; Nehmann, N; Schumacher, U; Valentiner, U | 1 |
| Ausserlechner, MJ; Bodner, M; David, R; Geiger, K; Hagenbuchner, J; Meister, B; Obexer, P; Porto, V; Villunger, A | 1 |
| He, Q; Lin, M; Luo, P; Shen, J; Wang, Z; Yang, B; Zhu, D | 1 |
| He, Q; Li, L; Lin, M; Luo, P; Yang, B | 1 |
| Bachmann, AS; Ibarra-Rivera, TR; Opoku-Ansah, J; Pirrung, MC | 1 |
| Bai, L; Du, BY; Miao, SY; Shen, Y; Song, W; Wang, LF | 1 |
| Badgett, TC; Chen, QR; Cheuk, AT; Khan, J; Song, YK; Tsang, PS; Wei, JS | 1 |
| Berezniuk, I; Castro, LM; Dasgupta, S; Ferro, ES; Fricker, LD; Gelman, JS; Gozzo, FC; Sironi, J | 1 |
| Behrens, D; Cinatl, J; Doerr, HW; Fichtner, I; Haider, W; Mack, A; Michaelis, M; Rothweiler, F | 1 |
| Arnold, AC; Back, TC; Hixon, JA; Khan, T; Lincoln, E; Lockett, S; Powell, D; Salcedo, R; Sayers, TJ; Stauffer, JK; Wigginton, JM; Williams, R | 1 |
| Brignole, C; Cilli, M; Cioni, M; Corrias, MV; Di Paolo, D; Marimpietri, D; Nico, B; Pagnan, G; Pastorino, F; Pezzolo, A; Piccardi, F; Pistoia, V; Ponzoni, M; Ribatti, D | 1 |
| Davidoff, AM; Dickson, PV; Hamner, JB; Ng, CY; Sims, TL; Spence, Y; Zhou, J | 1 |
| Benos, DJ; Sapirstein, VS | 1 |
| Cragoe, E; O'Donnell, ME; Villereal, ML | 1 |
| O'Donnell, ME; Villereal, ML | 1 |
27 other study(ies) available for pyrazines and Neuroblastoma
| Article | Year |
|---|---|
Aberrantly expressed Bruton's tyrosine kinase preferentially drives metastatic and stem cell-like phenotypes in neuroblastoma cells.
Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Benzamides; Carcinogenesis; Caspase 3; Cell Line, Tumor; Cell Movement; Cisplatin; Female; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Male; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Stem Cells; Neuroblastoma; Phenotype; Prognosis; Proto-Oncogene Proteins c-akt; Pyrazines; Spheroids, Cellular; STAT3 Transcription Factor | 2020 |
Pyrazinium thioacetate capped gold nanoparticles as Fe(III) sensor and Fe(III) marked anti-proliferating agent in human neuroblastoma cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ferric Compounds; Gold; Humans; Limit of Detection; Metal Nanoparticles; Neuroblastoma; Pyrazines; Sulfhydryl Compounds | 2019 |
Panobinostat synergistically enhances the cytotoxic effects of cisplatin, doxorubicin or etoposide on high-risk neuroblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; G2 Phase Cell Cycle Checkpoints; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Neuroblastoma; Panobinostat; Phenylurea Compounds; Protein Kinases; Pyrazines | 2013 |
HO-1 up-regulation: a key point in high-risk neuroblastoma resistance to bortezomib.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance, Neoplasm; Heme Oxygenase-1; Humans; N-Myc Proto-Oncogene Protein; Neuroblastoma; NF-E2-Related Factor 2; Nuclear Proteins; Oncogene Proteins; Pyrazines; Risk; Up-Regulation | 2014 |
New role for the mitochondrial peptide humanin: protective agent against chemotherapy-induced side effects.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Development; Boronic Acids; Bortezomib; Humans; Intracellular Signaling Peptides and Proteins; Male; Medulloblastoma; Neuroblastoma; Proteasome Inhibitors; Pyrazines | 2014 |
Protective role of humanin on bortezomib-induced bone growth impairment in anticancer treatment.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Development; Boronic Acids; Bortezomib; Cell Line, Tumor; Chondrocytes; Dose-Response Relationship, Drug; Drug Administration Schedule; Femur; Growth Plate; Heterografts; Humans; Intracellular Signaling Peptides and Proteins; Male; Medulloblastoma; Metatarsal Bones; Mice; Mice, Nude; Neuroblastoma; Proteasome Inhibitors; Pyrazines; Time Factors | 2014 |
sTRAIL coupled to liposomes improves its pharmacokinetic profile and overcomes neuroblastoma tumour resistance in combination with Bortezomib.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Female; Humans; Liposomes; Mice; Mice, Nude; Neuroblastoma; Pyrazines; TNF-Related Apoptosis-Inducing Ligand | 2014 |
Tetramethylpyrazine promotes SH-SY5Y cell differentiation into neurons through epigenetic regulation of Topoisomerase IIβ.
Topics: Acetylation; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epigenesis, Genetic; Histones; Humans; Neurites; Neuroblastoma; Neurons; Pyrazines | 2014 |
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
Topics: Animals; Antineoplastic Agents; Benzeneacetamides; beta Catenin; Brain Neoplasms; Camptothecin; Celecoxib; Cisplatin; Colorectal Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glucose-6-Phosphate Isomerase; Heterocyclic Compounds, 3-Ring; Humans; Immunoblotting; Immunohistochemistry; Irinotecan; Medulloblastoma; Mice; Neoplasm Transplantation; Neoplasms; Neuroblastoma; Pyrans; Pyrazines; Pyridines; Real-Time Polymerase Chain Reaction; Sulfones; Temozolomide; Triazoles; Tumor Suppressor Proteins; Vincristine; Wnt Proteins; Wnt Signaling Pathway | 2015 |
Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity.
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Imidazoles; Molecular Chaperones; Mutation; Neoplasm Proteins; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Pyrazines; Pyridines; Tumor Suppressor Protein p53 | 2008 |
Bortezomib as a therapeutic candidate for neuroblastoma.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Boronic Acids; Bortezomib; Brain Neoplasms; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Survival; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Genes, p53; Humans; Irinotecan; Neuroblastoma; NF-kappa B; Pyrazines | 2008 |
The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Endoplasmic Reticulum; Fenretinide; Humans; Mice; Neuroblastoma; Pyrazines; Xenograft Model Antitumor Assays | 2009 |
Effects of bortezomib on human neuroblastoma cells in vitro and in a metastatic xenograft model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Movement; Cell Proliferation; Female; Humans; Immunoenzyme Techniques; Male; Mice; Mice, SCID; Mitosis; Neuroblastoma; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
The anti-apoptotic protein BCL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Boronic Acids; Bortezomib; Caspases; Cell Line, Tumor; Child; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Neuroblastoma; Protease Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Receptors, Death Domain; Signal Transduction; Transgenes | 2010 |
Bortezomib induces apoptosis in human neuroblastoma CHP126 cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Boronic Acids; Bortezomib; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Humans; Indicators and Reagents; Neuroblastoma; NF-kappa B; Oncogene Protein p21(ras); Poly(ADP-ribose) Polymerases; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
The proteasome inhibitor bortezomib enhances ATRA-induced differentiation of neuroblastoma cells via the JNK mitogen-activated protein kinase pathway.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cell Differentiation; Cell Line, Tumor; Drug Synergism; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Neuroblastoma; Protease Inhibitors; Pyrazines; Rats; Tretinoin; Xenograft Model Antitumor Assays | 2011 |
Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Multiple Myeloma; Neuroblastoma; Peptides, Cyclic; Proteasome Inhibitors; Pyrazines; Urea | 2012 |
Synergistic effects of combination treatment with bortezomib and doxorubicin in human neuroblastoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Synergism; Humans; Neuroblastoma; Pyrazines | 2012 |
Synthetic lethal screen identifies NF-κB as a target for combination therapy with topotecan for patients with neuroblastoma.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Caspase 3; Cell Line, Tumor; Cell Proliferation; Mice; Mice, SCID; Microarray Analysis; Neuroblastoma; NF-kappa B; Pyrazines; RNA, Small Interfering; Topoisomerase I Inhibitors; Topotecan; Xenograft Model Antitumor Assays | 2012 |
Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomib.
Topics: Amino Acid Sequence; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; HEK293 Cells; Humans; Molecular Sequence Data; Neuroblastoma; Peptides; Proteasome Inhibitors; Proteomics; Pyrazines | 2013 |
Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Boronic Acids; Bortezomib; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Neuroblastoma; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Vincristine | 2006 |
Proteasome inhibition to maximize the apoptotic potential of cytokine therapy for murine neuroblastoma tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Cytokines; Disease Models, Animal; Growth Inhibitors; Interleukin-12; Interleukin-2; Liver Neoplasms; Male; Mice; Mice, Inbred A; Neuroblastoma; Proteasome Inhibitors; Pyrazines | 2006 |
Effect of bortezomib on human neuroblastoma cell growth, apoptosis, and angiogenesis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Mice; Mitotic Index; Neovascularization, Pathologic; Neuroblastoma; Protease Inhibitors; Pyrazines; Transplantation, Heterologous; Tumor Stem Cell Assay | 2006 |
Bortezomib inhibits angiogenesis and reduces tumor burden in a murine model of neuroblastoma.
Topics: Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Humans; In Vitro Techniques; Male; Mice; Mice, SCID; Neovascularization, Pathologic; Neuroblastoma; Pyrazines; Soft Tissue Neoplasms; Subcutaneous Tissue; Xenograft Model Antitumor Assays | 2007 |
Characteristics of an amiloride-sensitive sodium entry pathway in cultured rodent glial and neuroblastoma cells.
Topics: Amiloride; Animals; Biological Transport; Blood; Calcimycin; Cell Division; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Fenfluramine; Glioma; Kinetics; Mice; Neuroblastoma; Neurons; Pyrazines; Rats; Sodium | 1983 |
Inhibition of Na+ influx and DNA synthesis in human fibroblasts and neuroblastoma-glioma hybrid cells by amiloride analogs.
Topics: Amiloride; Animals; Cell Line; DNA Replication; Fibroblasts; Glioma; Humans; Hybrid Cells; Neuroblastoma; Pyrazines; Sodium | 1983 |
Membrane potential and sodium flux in neuroblastoma X glioma hybrid cells: effects of amiloride and serum.
Topics: Amiloride; Animals; Blood; Cell Line; Dose-Response Relationship, Drug; Glioma; Hybrid Cells; Membrane Potentials; Mice; Neuroblastoma; Pyrazines; Rats; Sodium; Thymidine | 1982 |