xanthine has been researched along with Neuroblastoma in 2 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although chlorpromazine was shown to greatly inhibit a Ca2+-mediated cell death at favorable concentrations (10(-6)-10(-5) M), it caused a drastic decrease in cell viability at higher concentrations (10(-4)-10(-3) M) in a human neuroblastoma cell line." | 7.67 | Biphasic effects of chlorpromazine on cell viability in a neuroblastoma cell line. ( Abe, K; Kogure, K; Sekizawa, T, 1986) |
| "Although chlorpromazine was shown to greatly inhibit a Ca2+-mediated cell death at favorable concentrations (10(-6)-10(-5) M), it caused a drastic decrease in cell viability at higher concentrations (10(-4)-10(-3) M) in a human neuroblastoma cell line." | 3.67 | Biphasic effects of chlorpromazine on cell viability in a neuroblastoma cell line. ( Abe, K; Kogure, K; Sekizawa, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hodges, SD | 1 |
| Fung, E | 1 |
| Lin, CC | 1 |
| Snyder, FF | 1 |
| Abe, K | 1 |
| Sekizawa, T | 1 |
| Kogure, K | 1 |
2 other studies available for xanthine and Neuroblastoma
| Article | Year |
|---|---|
Increased inosinate dehydrogenase activity in mycophenolic acid resistant neuroblastoma cells.
Topics: Animals; Cell Line; Drug Resistance; IMP Dehydrogenase; Ketone Oxidoreductases; Mice; Mycophenolic A | 1986 |
Biphasic effects of chlorpromazine on cell viability in a neuroblastoma cell line.
Topics: Calcium; Cell Line; Cell Membrane Permeability; Cell Survival; Chlorpromazine; Humans; Lipid Peroxid | 1986 |