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prazosin and Neuroblastoma

prazosin has been researched along with Neuroblastoma in 3 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Clonidine was a partial agonist."1.30Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells. ( Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amar, M1
Mallick, BN1
Parsley, S1
Gazi, L1
Bobirnac, I1
Loetscher, E1
Schoeffter, P1
Kazmi, SM1
Mishra, RK1

Other Studies

3 other studies available for prazosin and Neuroblastoma

ArticleYear
Mechanism of noradrenaline-induced α1-adrenoceptor mediated regulation of Na-K ATPase subunit expression in Neuro-2a cells.
    Brain research bulletin, 2018, Volume: 139

    Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Antagonists; Animals; Calcium; Cell Line, Tumor; Cell

2018
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
    European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Br

1999
Identification of alpha 2-adrenergic receptor sites in human retinoblastoma (Y-79) and neuroblastoma (SH-SY5Y) cells.
    Biochemical and biophysical research communications, 1989, Feb-15, Volume: 158, Issue:3

    Topics: Binding, Competitive; Cell Membrane; Clonidine; Epinephrine; Guanylyl Imidodiphosphate; Humans; Neur

1989