prazosin has been researched along with Neuroblastoma in 3 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Excerpt | Relevance | Reference |
---|---|---|
"Clonidine was a partial agonist." | 1.30 | Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells. ( Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Amar, M | 1 |
Mallick, BN | 1 |
Parsley, S | 1 |
Gazi, L | 1 |
Bobirnac, I | 1 |
Loetscher, E | 1 |
Schoeffter, P | 1 |
Kazmi, SM | 1 |
Mishra, RK | 1 |
3 other studies available for prazosin and Neuroblastoma
Article | Year |
---|---|
Mechanism of noradrenaline-induced α1-adrenoceptor mediated regulation of Na-K ATPase subunit expression in Neuro-2a cells.
Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Antagonists; Animals; Calcium; Cell Line, Tumor; Cell | 2018 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Br | 1999 |
Identification of alpha 2-adrenergic receptor sites in human retinoblastoma (Y-79) and neuroblastoma (SH-SY5Y) cells.
Topics: Binding, Competitive; Cell Membrane; Clonidine; Epinephrine; Guanylyl Imidodiphosphate; Humans; Neur | 1989 |